Protein Alignment FeCH and hemH

DIOPT Version :10

• Sequence 1: NP_524613.1
• Gene: FeCH / 43757
• FlyBaseID: FBgn0266268
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_415008.1
• Gene: hemH / 947532
• ECOCYCID: EG10431
• Length: 320
• Species: Escherichia coli
• Alignment Length: 334
• Identity: 88/334 - (26%)
• Similarity: 155/334 - (46%)
• Gaps: 30/334 - (8%)

  Fly    25 QKPKTAILMLNMGGP--THTDQVHDYLLRIMTDRDMIQLPVQSRLGPW------IAQRRTPEVQK 81
            ::.||.||:.|:|.|  ...:.|..||.:.::||.::.   .|||..|      |...|:|.|.|
E. coli     2 RQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVD---TSRLLWWPLLRGVILPLRSPRVAK 63

  Fly    82 KYKEI--GGGSPILKWTELQGQLMCEQLDRISPETAPHKHYVGFRYVNPLTENTLAEIEKDKPER 144
            .|..:  .||||::.::..|.|.:.::|    ||...   .:|..|.:|..|:.:.|:..:..:.
E. coli    64 LYASVWMEGGSPLMVYSRQQQQALAQRL----PEMPV---ALGMSYGSPSLESAVDELLAEHVDH 121

  Fly   145 VVLFSQYPQYSCATSGSSFNSIFTHY-RSNNLPSDIKWSIIDRWGTHPLLIKTFAQRIRDELAKF 208
            :|:...|||:||:|.|:.::.:.... |..::|.   .|.|..:..:...|...|..:|...||.
E. coli   122 IVVLPLYPQFSCSTVGAVWDELARILARKRSIPG---ISFIRDYADNHDYINALANSVRASFAKH 183

  Fly   209 VETKRNDVVILFTAHSLPLKAVNRGDAYPSEIGASVHMVMQELGQT-NPYSLAWQSKVGPLPWLA 272
            .|..    ::|.:.|.:|.:..:.||.||.....:...:...||.. ....:.:||:.|..|||.
E. coli   184 GEPD----LLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLM 244

  Fly   273 PATDDAIKGYVKQGLKNFILVPIAFVNEHIETLHELDIEYCDELAKEVGVEEIRRAATPNDHPLF 337
            |.||:.:|...::|:.:..::...|..:.:|||.|: .|...|:....|.::.......|..|..
E. coli   245 PYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEI-AEQNREVFLGAGGKKYEYIPALNATPEH 308

  Fly   338 IDALTNVVA 346
            |:.:.|:||
E. coli   309 IEMMANLVA 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FeCH	NP_524613.1	Ferrochelatase	29..349	CDD:459929	87/330 (26%)
hemH	NP_415008.1	hemH	1..320	CDD:272909	88/334 (26%)