Protein Alignment FeCH and Fech

DIOPT Version :10

• Sequence 1: NP_524613.1
• Gene: FeCH / 43757
• FlyBaseID: FBgn0266268
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: XP_006254912.1
• Gene: Fech / 361338
• RGDID: 1307556
• Length: 453
• Species: Rattus norvegicus
• Alignment Length: 354
• Identity: 199/354 - (56%)
• Similarity: 267/354 - (75%)
• Gaps: 0/354 - (0%)

  Fly    25 QKPKTAILMLNMGGPTHTDQVHDYLLRIMTDRDMIQLPVQSRLGPWIAQRRTPEVQKKYKEIGGG 89
            :||||.|||||||||....:|.|:|.|:..|||::.||:|::|.|:||:||||::|::|:.||||
  Rat    95 RKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGG 159

  Fly    90 SPILKWTELQGQLMCEQLDRISPETAPHKHYVGFRYVNPLTENTLAEIEKDKPERVVLFSQYPQY 154
            |||..||..||:.|.:.||.:||:|||||:|:|||||:||||..:.|:|:|..||.:.|:|||||
  Rat   160 SPIKMWTSKQGEGMVKLLDELSPDTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQY 224

  Fly   155 SCATSGSSFNSIFTHYRSNNLPSDIKWSIIDRWGTHPLLIKTFAQRIRDELAKFVETKRNDVVIL 219
            ||:|:|||.|:|:.:|........:|||.||||.||||||:.||..|..||..|.|.||::||||
  Rat   225 SCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPEEKRSEVVIL 289

  Fly   220 FTAHSLPLKAVNRGDAYPSEIGASVHMVMQELGQTNPYSLAWQSKVGPLPWLAPATDDAIKGYVK 284
            |:|||||:..|||||.||.|:||:||.||::||..|||.|.|||||||:|||.|.||:||||..:
  Rat   290 FSAHSLPMSVVNRGDPYPQEVGATVHRVMEQLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCE 354

  Fly   285 QGLKNFILVPIAFVNEHIETLHELDIEYCDELAKEVGVEEIRRAATPNDHPLFIDALTNVVADHL 349
            :|.||.:||||||.::|||||:||||||...||::.|.|.||||.:.|.:|||..||.::|..|:
  Rat   355 RGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHI 419

  Fly   350 KSQQAVNPKFLMRCPMCSNPKCRESKSWY 378
            :|.:..:.:..:.||:|.||.||::||::
  Rat   420 QSNKLCSTQLSLSCPLCVNPVCRKTKSFF 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FeCH	NP_524613.1	Ferrochelatase	29..349	CDD:459929	185/319 (58%)
Fech	XP_006254912.1	Ferrochelatase	99..419	CDD:459929	185/319 (58%)