Protein Alignment FeCH and hem15

DIOPT Version :9

• Sequence 1: NP_524613.1
• Gene: FeCH / 43757
• FlyBaseID: FBgn0266268
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_587720.1
• Gene: hem15 / 2539199
• PomBaseID: SPCC320.09
• Length: 384
• Species: Schizosaccharomyces pombe
• Alignment Length: 364
• Identity: 169/364 - (46%)
• Similarity: 242/364 - (66%)
• Gaps: 4/364 - (1%)

  Fly    17 GGVRNLSGQKPKTAILMLNMGGPTHTDQVHDYLLRIMTDRDMIQLP-VQSRLGPWIAQRRTPEVQ 80
            |..:::||:.| ||::|:|||||::.|:|..:|.|:.||.|:|.|. .|:.||.:||:||||:||
pombe    22 GVTKSVSGKGP-TAVVMMNMGGPSNLDEVGPFLERLFTDGDIIPLGYFQNSLGKFIAKRRTPKVQ 85

  Fly    81 KKYKEIGGGSPILKWTELQGQLMCEQLDRISPETAPHKHYVGFRYVNPLTENTLAEIEKDKPERV 145
            ..|.:||||||||.||.:||..||:.||:..||:|||..:|.|||..||||:.|.|::|....|.
pombe    86 NHYSDIGGGSPILHWTRIQGSEMCKILDKKCPESAPHLPFVAFRYAPPLTEDMLDELKKANVSRA 150

  Fly   146 VLFSQYPQYSCATSGSSFNSIFTHYRSNNLPSDIKWSIIDRWGTHPLLIKTFAQRIRDELAKFVE 210
            |.||||||:||||||:|.|.:........:..|.:|||:|||.....||..||:.|.:.|..:.|
pombe   151 VAFSQYPQWSCATSGASLNELRRKLIEKGMEKDFEWSIVDRWPLQQGLINAFAENIEETLKTYPE 215

  Fly   211 TKRNDVVILFTAHSLPLKAVNRGDAYPSEIGASVHMVMQELGQTNPYSLAWQSKVGPLPWLAPAT 275
            ..|:||||:|:|||||:..|.:||.|..||.|:...||:.|...|.:..|||||||||||::|||
pombe   216 DVRDDVVIVFSAHSLPMSQVAKGDPYVYEIAATSQAVMKRLNYKNKFVNAWQSKVGPLPWMSPAT 280

  Fly   276 DDAIKGYVKQGLKNFILVPIAFVNEHIETLHELDIEYCDELAKEVGVEEIRRAATPNDHPLFIDA 340
            |..|:....:|.||.|||||||.::|||||.||: :|.:: ||:.|:..::|.::.|.....|..
pombe   281 DFVIEQLGNRGQKNMILVPIAFTSDHIETLKELE-DYIED-AKQKGITGVKRVSSINGSMTAIQG 343

  Fly   341 LTNVVADHLKSQQAVNPKFLMRCPMCSNPKCRESKSWYR 379
            :.::||:|||::...:.:|..|||.|::..|.|..::::
pombe   344 MADLVAEHLKAKVPYSRQFTQRCPGCTSESCAERINFFQ 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FeCH	NP_524613.1	Ferrochelatase	29..349	CDD:279146	155/320 (48%)
		Ferrochelatase_N	29..190	CDD:239504	84/161 (52%)
		Ferrochelatase_C	195..332	CDD:238240	65/136 (48%)
hem15	NP_587720.1	Ferrochelatase	33..352	CDD:279146	155/320 (48%)
		Ferrochelatase_N	33..193	CDD:239504	83/159 (52%)
		Ferrochelatase_C	200..335	CDD:238240	65/136 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	307	1.000	Domainoid score	I249
eggNOG	1	0.900	-	-		E1_COG0276
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H113
Inparanoid	1	1.050	332	1.000	Inparanoid score	I513
OMA	1	1.010	-	-		QHG62486
OrthoFinder	1	1.000	-	-		FOG0004364
OrthoInspector	1	1.000	-	-		oto101191
orthoMCL	1	0.900	-	-		OOG6_101310
Panther	1	1.100	-	-	LDO	PTHR11108
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R558
SonicParanoid	1	1.000	-	-		X3086
TreeFam	1	0.960	-	-
	14	13.860