Protein Alignment Rift and SLC52A1

DIOPT Version :10

• Sequence 1: NP_651901.3
• Gene: Rift / 43756
• FlyBaseID: FBgn0039882
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_060456.3
• Gene: SLC52A1 / 55065
• HGNCID: 30225
• Length: 448
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 155/435 - (35%)
• Similarity: 229/435 - (52%)
• Gaps: 34/435 - (7%)

  Fly    75 LVDVLAIFFGIGTWLGVNGTFIQLPLLVDEAPEGWSLPSYLSVMVQIGNLGPLLYTAIQKYSPKK 139
            |..:|...||:|:|..|||.:::||::|.:.||||||||||||:|.:||||.|:.|..::.:|.|
Human    11 LTHLLVALFGMGSWAAVNGIWVELPVVVKDLPEGWSLPSYLSVVVALGNLGLLVVTLWRQLAPGK 75

  Fly   140 LNDGWTIHGVLLVGAISCLLTAFFYNQTASVAGTDHSLALFLLTCFTALNACTSSVLFMPYMGRF 204
             .:...|..|.::..:...|.|..::..|.|||..||:|...|....|:..|||:|.|:|::...
Human    76 -GEQVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHSVAFLTLALVLAMACCTSNVTFLPFLSHL 139

  Fly   205 KEQYMVTYFIGEGLSGLLPSVTALIQGIGESGDC--VLVNVTESGEEVYALRKTPPRFDTRVFFL 267
            ...::.::|:|:|||.|||.|.||:||:|.. :|  ...|.| ||..:    ..|.||....||.
Human   140 PPPFLRSFFLGQGLSALLPCVLALVQGVGRL-ECPPAPTNGT-SGPPL----DFPERFPASTFFW 198

  Fly   268 ILFALMVLAYVGY----ALLNSLPLA--------------------RREYAQVTVSEGNKYVYGE 308
            .|.||:|.:...:    .||.|||..                    :.|...:.:.|......|.
Human   199 ALTALLVTSAAAFRGLLLLLPSLPSVTTGGSGPELQLGSPGAEEEEKEEEEALPLQEPPSQAAGT 263

  Fly   309 ADN-QPKAEKLSKGQYTYLLLLIGAISLFSNGMFGSIQSYSSAPYGSQAYHLAATLSVIANPVAC 372
            ... .|:|.:|......:||.|:...|..:||:..|:||:|..|||..|||||..|...|||:||
Human   264 IPGPDPEAHQLFSAHGAFLLGLMAFTSAVTNGVLPSVQSFSCLPYGRLAYHLAVVLGSAANPLAC 328

  Fly   373 FMAMFLHFTSLRIITVLSILAGLLTSYVFTTAALSPLPPLHDQTVGAVLVVTAWTLLVGIVSYTK 437
            |:||.:...||..:..||:|..|..:|:...|.|||.|||...|.|.||||.:|.|.:.:.||.|
Human   329 FLAMGVLCRSLAGLVGLSLLGMLFGAYLMALAILSPCPPLVGTTAGVVLVVLSWVLCLCVFSYVK 393

  Fly   438 LGITTVMRAQGGQSLVWVGAITQLGSAIGAVAIFFAINYSDLFQA 482
            :..::::...|..:|:..|...|:||.:||.|:|...:...:||:
Human   394 VAASSLLHGGGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQS 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rift	NP_651901.3	DUF1011	320..418	CDD:461856	42/97 (43%)
SLC52A1	NP_060456.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..267		3/41 (7%)
		DUF1011	276..374	CDD:461856	42/97 (43%)