Protein Alignment Rift and SLC52A1

DIOPT Version :9

• Sequence 1: NP_651901.3
• Gene: Rift / 43756
• FlyBaseID: FBgn0039882
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001098047.1
• Gene: SLC52A1 / 55065
• HGNCID: 30225
• Length: 448
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 155/435 - (35%)
• Similarity: 229/435 - (52%)
• Gaps: 34/435 - (7%)

  Fly    75 LVDVLAIFFGIGTWLGVNGTFIQLPLLVDEAPEGWSLPSYLSVMVQIGNLGPLLYTAIQKYSPKK 139
            |..:|...||:|:|..|||.:::||::|.:.||||||||||||:|.:||||.|:.|..::.:|.|
Human    11 LTHLLVALFGMGSWAAVNGIWVELPVVVKDLPEGWSLPSYLSVVVALGNLGLLVVTLWRQLAPGK 75

  Fly   140 LNDGWTIHGVLLVGAISCLLTAFFYNQTASVAGTDHSLALFLLTCFTALNACTSSVLFMPYMGRF 204
             .:...|..|.::..:...|.|..::..|.|||..||:|...|....|:..|||:|.|:|::...
Human    76 -GEQVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHSVAFLTLALVLAMACCTSNVTFLPFLSHL 139

  Fly   205 KEQYMVTYFIGEGLSGLLPSVTALIQGIGESGDC--VLVNVTESGEEVYALRKTPPRFDTRVFFL 267
            ...::.::|:|:|||.|||.|.||:||:|.. :|  ...|.| ||..:    ..|.||....||.
Human   140 PPPFLRSFFLGQGLSALLPCVLALVQGVGRL-ECPPAPTNGT-SGPPL----DFPERFPASTFFW 198

  Fly   268 ILFALMVLAYVGY----ALLNSLPLA--------------------RREYAQVTVSEGNKYVYGE 308
            .|.||:|.:...:    .||.|||..                    :.|...:.:.|......|.
Human   199 ALTALLVTSAAAFRGLLLLLPSLPSVTTGGSGPELQLGSPGAEEEEKEEEEALPLQEPPSQAAGT 263

  Fly   309 ADN-QPKAEKLSKGQYTYLLLLIGAISLFSNGMFGSIQSYSSAPYGSQAYHLAATLSVIANPVAC 372
            ... .|:|.:|......:||.|:...|..:||:..|:||:|..|||..|||||..|...|||:||
Human   264 IPGPDPEAHQLFSAHGAFLLGLMAFTSAVTNGVLPSVQSFSCLPYGRLAYHLAVVLGSAANPLAC 328

  Fly   373 FMAMFLHFTSLRIITVLSILAGLLTSYVFTTAALSPLPPLHDQTVGAVLVVTAWTLLVGIVSYTK 437
            |:||.:...||..:..||:|..|..:|:...|.|||.|||...|.|.||||.:|.|.:.:.||.|
Human   329 FLAMGVLCRSLAGLVGLSLLGMLFGAYLMALAILSPCPPLVGTTAGVVLVVLSWVLCLCVFSYVK 393

  Fly   438 LGITTVMRAQGGQSLVWVGAITQLGSAIGAVAIFFAINYSDLFQA 482
            :..::::...|..:|:..|...|:||.:||.|:|...:...:||:
Human   394 VAASSLLHGGGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQS 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rift	NP_651901.3	DUF1011	320..418	CDD:283816	42/97 (43%)
SLC52A1	NP_001098047.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..267		3/41 (7%)
		DUF1011	280..374	CDD:368808	42/93 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148949
Domainoid	1	1.000	79	1.000	Domainoid score	I8664
eggNOG	1	0.900	-	-		E1_KOG4255
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52392
OrthoDB	1	1.010	-	-		D356719at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12929
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1135
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.820