Protein Alignment CG42233 and CG8001

DIOPT Version :10

• Sequence 1: NP_651899.2
• Gene: CG42233 / 43754
• FlyBaseID: FBgn0250755
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_647657.1
• Gene: CG8001 / 38224
• FlyBaseID: FBgn0035268
• Length: 748
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 126/543 - (23%)
• Similarity: 210/543 - (38%)
• Gaps: 149/543 - (27%)

  Fly    53 TRNLDVALSQRENILV------AGHLPSAIFRERLSAAQNLYQR-----NLTGHYGCVNALEFSS 106
            |.|.|..|.|||:.::      .||..::.|.:....::.:.::     :|..|:||||:|.|:.
  Fly   272 TWNYDQELLQREHNIINRIDWRGGHTSASSFGQGYYGSRQVVEQMTLLSSLNVHHGCVNSLNFNR 336

  Fly   107 GGQFLASGGDDKRVLLWNIDRELVSKLGKPRSMNEKHASNIFCLGFDTQNSYIFSGGNDDLVIQH 171
            .|..:.||.||..:::|:..:|  .:|.:.||   .|..|||      |..:|.|.|..|:|  .
  Fly   337 AGDLICSGSDDLTIVVWDWAKE--KQLHRFRS---GHNMNIF------QTKFIDSAGCLDIV--S 388

  Fly   172 DLETGKI--------------LNHFSHDGPVYGLSVDRISGHLLSVATEHGEILVYDLRAGKSEP 222
            ....|::              :..::|...|:.:.|...|.|.|..|.|...:..:||||..:
  Fly   389 SSRDGQVRRSVIPPSGGVIKPIRLYTHSESVHKIIVVPHSRHELMSAGEDAAVKHFDLRASNA-- 451

  Fly   223 LAIAKFKTPFNAVEFHPLNGNFLATANAKRGAMLWDLRHHQQALCQYNYIPESPSCMS-----VR 282
             |....:..:|             ..|.:....|:.:.||.       |.||  .|:|     :|
  Fly   452 -ATTMMRCVYN-------------DENERGRVRLFSIAHHP-------YAPE--FCVSGSDDILR 493

  Fly   283 FNCNGTLLLTLHRRLPPIL------------YSPGAPEPVATFYHDE------------------ 317
            ......|...:|:..|..|            |:....|.:|: |.|.
  Fly   494 VYDKRNLAKAIHQMAPRNLLEAQITQITCAVYNHSGSEILAS-YSDAGIYLFDSRNYNRGDYLHC 557

  Fly   318 ---YFNSCTMKSCTFAGPQDELVVSGSDNFNMFIWRLEGVDLDEKNQWMETTPVIL----AGHRS 375
               :.||.|:|...|.||:.|.:|||||..|:|.|        :||     |..|:    ..|..
  Fly   558 YKGHINSRTIKGVNFFGPRSEYIVSGSDCGNIFFW--------DKN-----TEAIINYMKGDHVG 609

  Fly   376 IVNQVRYNRERCLLASSGVEKIIKLWSPFAQQGWEGSLTQAEALPYCTRALYRESSDHVSQDFSA 440
            :||.:..:....:||:||:|..:|:|:|   ||.|..|.:         .|.:::   :.::|..
  Fly   610 VVNCLEPHPWMPVLATSGLEHDVKIWTP---QGPERKLPE---------DLLKQT---LQRNFRC 659

  Fly   441 RSTDEDQVMLAFFDTLVQHELES----------WSTVDNQNSSKSSTHTSTCSEASSPTEEPSDE 495
            ...:...:.:..|...::..|:.          .|::.:|....||:. |..|.||:||....:.
  Fly   660 NIVESIDLDINNFQYFIRGFLQGSGASHLRQRHTSSLGHQMRDNSSSR-SNGSNASNPTSHRRNS 723

  Fly   496 EDQDPQTDRNQNEENVQDQDIDT 518
            ...|...|...:    .|..:||
  Fly   724 NSSDDTNDEGAD----ADAALDT 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42233	NP_651899.2	WD40	2..403	CDD:441893	102/416 (25%)
		WD40 repeat	56..91	CDD:293791	8/45 (18%)
		WD40 repeat	100..142	CDD:293791	13/41 (32%)
		WD40 repeat	147..183	CDD:293791	9/49 (18%)
		WD40 repeat	191..225	CDD:293791	10/33 (30%)
		WD40 repeat	232..270	CDD:293791	5/37 (14%)
		WD40 repeat	278..371	CDD:293791	32/134 (24%)
		WD40 repeat	377..401	CDD:293791	8/23 (35%)
CG8001	NP_647657.1	WD40	318..635	CDD:475233	91/368 (25%)
		WD40 repeat	331..367	CDD:293791	12/40 (30%)
		WD40 repeat	373..414	CDD:293791	8/48 (17%)
		WD40 repeat	419..462	CDD:293791	13/58 (22%)
		WD40 repeat	472..513	CDD:293791	11/49 (22%)
		WD40 repeat	520..559	CDD:293791	5/39 (13%)
		WD40 repeat	567..594	CDD:293791	13/34 (38%)
		WD40 repeat	611..657	CDD:293791	15/60 (25%)