Protein Alignment CG42233 and Dcaf8l

DIOPT Version :9

• Sequence 1: NP_651899.2
• Gene: CG42233 / 43754
• FlyBaseID: FBgn0250755
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_032847.2
• Gene: Dcaf8l / 18630
• MGIID: 101758
• Length: 747
• Species: Mus musculus
• Alignment Length: 501
• Identity: 118/501 - (23%)
• Similarity: 195/501 - (38%)
• Gaps: 133/501 - (26%)

  Fly    45 WRNLRSLETRNLDVALSQRENILVAGHLPSAIFRERLSAAQNLYQRNLTGHYGCVNALEFSSGGQ 109
            |..|.:|..|.|  ..|.|......|   :.:|.:|.| .:::::    ||.||||.:.|:..|.
Mouse   312 WNVLSALRDRQL--GSSGRFVYEACG---ARLFVQRFS-LEHVFE----GHSGCVNTVHFNQHGT 366

  Fly   110 FLASGGDDKRVLLWNIDRELVSKLGKPRSM---NEKHASNIFCLGF--DTQNSYIFSGGNDDLVI 169
            .||||.||.:|::|:        ..|.||:   :..|.:||....|  :..::.:...|.|..|.
Mouse   367 LLASGSDDLKVIVWD--------WLKKRSVLNFDSGHKNNILQAKFLPNCNDAILAMCGRDGQVR 423

  Fly   170 QHDLE-------TGKILNHFSHDGPVYGLSVDRISGHLLSVATEHGEILVYDLR-AGKSEPLAIA 226
            ...|.       |.:::   .|.|..:.|.::..|......:.|...:...||| |..:..|.:.
Mouse   424 VAQLSAVAGTHMTKRLV---KHGGASHRLGLEPDSPFRFLTSGEDAVVFNIDLRQAHPASKLLVI 485

  Fly   227 K-----------FKTPFNAVEFHPLNGNFLATANAKRGAMLWDLRHHQQALCQYNYIPESPSCMS 280
            |           |..|.|..:|        |.....:...::|.|.          |.|:.:...
Mouse   486 KDGDKKVGLYTVFVNPANVYQF--------AVGGQDQFMRIYDQRK----------IDENVNNGV 532

  Fly   281 VRFNCNGTLLLTLH-RRLPPILYSPGAPEPVATFYHDE---------------------YFNSCT 323
            ::..|...||.:.: ..:..::||....|.:|: |:||                     :.|:.|
Mouse   533 LKKFCPHHLLSSDYPAHITSLMYSYDGTEILAS-YNDEDIYIFNSSDSDGAQYAKRYKGHRNNST 596

  Fly   324 MKSCTFAGPQDELVVSGSDNFNMFIWRLEGVDLDEKN-----QWMETTPVILAGHRSIVNQVRYN 383
            :|...|.||:.|.|:||||..::|||        ||:     |::|      |.....:|.:..:
Mouse   597 VKGVYFYGPRSEFVMSGSDCGHIFIW--------EKSSCQIVQFLE------ADEGGTINCIDSH 647

  Fly   384 RERCLLASSGVEKIIKLWSPFAQQGWE-GSLTQAEALPYCTRALYRESSDHVSQDFSARSTD-ED 446
            ....:|||||::..:|:|||.|:...: ..|.....:....|           .:|:.|.|. .:
Mouse   648 PYLPVLASSGLDHEVKIWSPIAEPSKKLAGLKNVIKINKLKR-----------DNFTLRHTSLFN 701

  Fly   447 QVMLAFFDTLVQHELE-----SWSTV-------DNQNSSKSSTHTS 480
            ..||.|   |:.|..:     ||..:       |..:||.||..|:
Mouse   702 NSMLCF---LMSHVTQSNYGRSWRGIRINAGGGDFSDSSSSSEETN 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42233	NP_651899.2	WD40	<45..404	CDD:225201	98/409 (24%)
		WD40 repeat	56..91	CDD:293791	7/34 (21%)
		WD40	90..402	CDD:295369	85/362 (23%)
		WD40 repeat	100..142	CDD:293791	14/44 (32%)
		WD40 repeat	147..183	CDD:293791	7/44 (16%)
		WD40 repeat	191..225	CDD:293791	8/34 (24%)
		WD40 repeat	232..270	CDD:293791	5/37 (14%)
		WD40 repeat	278..371	CDD:293791	29/119 (24%)
		WD40 repeat	377..401	CDD:293791	7/23 (30%)
Dcaf8l	NP_032847.2	WD40	345..666	CDD:392136	85/368 (23%)
		WD40 repeat	358..394	CDD:293791	13/43 (30%)
		WD40 repeat	400..441	CDD:293791	6/43 (14%)
		WD40 repeat	446..487	CDD:293791	8/40 (20%)
		WD40 repeat	495..543	CDD:293791	11/65 (17%)
		WD40 repeat	550..589	CDD:293791	7/39 (18%)
		WD40 repeat	597..634	CDD:293791	16/44 (36%)
		WD40 repeat	641..665	CDD:293791	7/23 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270484at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920