DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir100a and Ir7d

DIOPT Version :9

Sequence 1:	NP_651898.2	Gene:	Ir100a / 43753	FlyBaseID:	FBgn0039879	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_001138175.1	Gene:	Ir7d / 7354416	FlyBaseID:	FBgn0259190	Length:	594	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	98/507 - (19%)
Similarity:	180/507 - (35%)	Gaps:	158/507 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 VQLSKKSVLLFNPFLQRLVVVQDSKTYSRIYKDLEGYHLRIYIFD-SVYSSVIGDGENKVLSVTG 205
            |::..|...|::.|.:||             |:|.|..|.:.::| ..|..:.....:.:..:.|
  Fly   187 VEIDIKDGDLWDVFPRRL-------------KNLHGCPLSVIVWDIPPYMRINWKSSDPMDGLDG 238

  Fly   206 ADAKLAKTVARQLNFTADFV--WPDDEFFGGRLANGEYSGG--VGRAHRGEVDIIFAGFFIK--D 264
            .|..|.:.|||::|||...:  .|:....|....||.::|.  :.|..|..:.|..|....:  .
  Fly   239 LDGLLLRIVARKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAYKMLRERRANITIGCAACTPERST 303

  Fly   265 YLTTHIQFSAAVYMDELCLYVKKAQRIPQSILPLFAVHMDVWLCFLLVGLLGALVWLILRAVNLI 329
            :|.....:|...|:  :.|..:....|.:  :.||......||  ||..:|| |.|::
  Fly   304 FLEATSPYSQMSYI--IVLQARGGYSIYE--VMLFPFEKYTWL--LLSTILG-LHWIV------- 354

  Fly   330 LGIEGVPDGSRATRISYFGAARRIFVDTWVIWVRVNVGRFPPFHSERIFVASLCLVSVIFGALLE 394
                    |||....|...|.       |::|               |||......:.:|..:..
  Fly   355 --------GSRWRMPSPILAG-------WMLW---------------IFVIRASYEASVFNFIQN 389

  Fly   395 SSLATVYIRPLYYRDVNTLRELDES---GQPIYIKHPAFKDDL----FYGHNSEVYRRLDAKMML 452
            |.     ::|       :.|.||::   |......|.:::..|    |.|..            |
  Fly   390 SP-----VKP-------SPRTLDQALSGGFRFITDHASYRMTLKIPSFQGKT------------L 430

  Fly   453 VAEGE-----ERLIEMVSKRGGFAGVTRSASLQLSDIRYVMTKKVHK-----IPECPKNYHIAYV 507
            ::.|:     :.|::...|.|.|     ::...|:|  :::..:.|:     :.|...:..:...
  Fly   431 ISAGQPVDVFDALLKAPWKTGAF-----TSRAFLAD--HLVRHRKHRNQLVILAEKIVDNMLCMY 488

  Fly   508 LPRPSPYLEEVNRIVLRLVAGGIVGLWTGEAKERAKWSIQRFPEYLAELDVGRWKVL-TLSDV-- 569
            .|..|.:..|:|:::..:.:.||               .|...:.||      |..| |.:|.
  Fly   489 FPHGSYFAWEINKLLFNMRSFGI---------------FQHHSQILA------WDNLPTTTDTDT 532

  Fly   570 ------------------QLAFYALTIGCLLSAIVCMAEILLGRQ---RRLH 600
                              .::|....:.||:.|: |::.::.|.:   ||.|
  Fly   533 PGKRIHSSTESVATGFAESMSFVVAALNCLMGAL-CISIVVFGLELLSRRRH 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir100a	NP_651898.2	Periplasmic_Binding_Protein_Type_2	210..>255	CDD:304360	14/48 (29%)
Ir100a	NP_651898.2	Lig_chan	<439..580	CDD:278489	24/171 (14%)
Ir7d	NP_001138175.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010