DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir100a and Ir92a

DIOPT Version :9

Sequence 1:	NP_651898.2	Gene:	Ir100a / 43753	FlyBaseID:	FBgn0039879	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	103/536 - (19%)
Similarity:	191/536 - (35%)	Gaps:	132/536 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 DVWLQHGHSRIYYVQLSKKSVLLFNPFLQRLVVVQDSKTYSRIYKDLEGYHLRI----YIFDSVY 189
            ::|.|.     :...:.....||.:.||.........:.|.....:|:...|.:    |:..::.
  Fly   201 ELWTQK-----FVGAVGNLDALLLDAFLPNETFANRVELYPNKLLNLQRRSLLVGSITYVPYTIT 260

  Fly   190 SSV-IGDGE---------NKVLSVTGADAKLAKTVARQLN-------FTADFVWPDDEFFGGRLA 237
            :.| .|.|:         |:.|:..||:|.:.||..:..|       :.|| .|      ||...
  Fly   261 NYVPAGQGDVDPIHPQWPNRSLTFDGAEANVMKTFCQVHNCHLRVEAYGAD-NW------GGIYD 318

  Fly   238 NGEYSGGVGRAHRGEVDIIFAGFFIKDYLTTHIQFSAAVYMDELCLY------VKKAQRIPQS-- 294
            |....|.:|..:...|::...                       |:|      .:.:..|.:|
  Fly   319 NESSDGMLGDIYEQRVEMAIG-----------------------CIYNWYDGITETSHTIARSSV 360

  Fly   295 -ILPLFAVHMDVWLCFLLVGLLGALVWLILRAVNLILG-----IEGVPDGSRATRISYFGA---- 349
             ||......:..|...::.  .....||:|.:..:|.|     ::.|     :.|:.|.|.
  Fly   361 TILGPAPAPLPSWRTNIMP--FNNRAWLVLISTLVICGTFLYFMKYV-----SYRLRYSGTQVKF 418

  Fly   350 --ARRI---FVDTWVIWVR-----VNVGRFPPFHSERIFVASLCLVSVIFGALLESSLATVYIRP 404
              :|::   .:|.:.::::     ::..||.|    |.|:|::...::....:....|.::...|
  Fly   419 HHSRKLEKSMLDIFALFIQQPSAPLSFDRFAP----RFFLATILCATITLENIYSGQLKSMLTFP 479

  Fly   405 LYYRDVNTLRELDESG-----QPIYIKHPAFKDDL----FYGHNSEVYRRLDAKMMLVAEGEERL 460
            .|...|:|:.:..:||     ..|...|.....||    ....|.||:             :...
  Fly   480 FYSAPVDTIEKWAQSGWKWSAPSIIWVHTVQSSDLETEQILARNFEVH-------------DYSY 531

  Fly   461 IEMVS--KRGGFAGVTRSASLQLSDIRYVMTKKVHKIPECPKNYHIAY---VLPRPSPYLEEVNR 520
            :..||  ...|| |:.|.:|..||...||.|:.:........:.:..|   |..|....:.|:|:
  Fly   532 LSNVSFMPNYGF-GIERLSSGSLSVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGWILMPELNK 595

  Fly   521 IVLRLVAGGIVGLWTGEAKERAKWSIQRFPEYLAELDVGRWKV------LTLSDVQLAFYALTIG 579
            .:......|:...|  |.:...|:..::..|.|.:|..|. ||      |.:.::..|.:.|..|
  Fly   596 HIRTCQETGLYFHW--ELEFIDKYMDKKKQEVLMDLANGH-KVKGAPQALDVRNIAGALFVLAFG 657

  Fly   580 CLLSAIVCMAEILLGR 595
            ...:....:||:|:.|
  Fly   658 VAFAGCALVAELLIHR 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir100a	NP_651898.2	Periplasmic_Binding_Protein_Type_2	210..>255	CDD:304360	12/51 (24%)
Ir100a	NP_651898.2	Lig_chan	<439..580	CDD:278489	33/151 (22%)
Ir92a	NP_001097845.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010