DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir100a and Ir48b

DIOPT Version :9

Sequence 1:	NP_651898.2	Gene:	Ir100a / 43753	FlyBaseID:	FBgn0039879	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_610697.1	Gene:	Ir48b / 36254	FlyBaseID:	FBgn0033648	Length:	600	Species:	Drosophila melanogaster

Alignment Length:	448	Identity:	78/448 - (17%)
Similarity:	142/448 - (31%)	Gaps:	177/448 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LELHLRTSEDGGN-DLVQFLMQEKSSIIISAKQEEVPSRAKIMRHHFFIFDGVHQMQEIRTSLFN 103
            :.|.:.||.:..| ..|::.:...:.:.:....||.|            :|.:|.:     :|..
  Fly    66 ISLMIFTSIESMNFTQVEYNLGADNKLFLIMGNEEPP------------YDFLHAL-----NLHF 113

  Fly   104 TDGFYILALENNT-IEDDVLLMEFAADVWLQHGHSRIYYVQLSKKSVLLFNPFLQRL-------- 159
            ....||:.::... ::.....::|...:| |.|     ||||     |::..:.::|
  Fly   114 QFAEYIIVIDEPVDLKKSTKWLDFVNHLW-QQG-----YVQL-----LIYTSYDEKLYHKIIFPE 167

  Fly   160 VVVQDS--KTYSRI---YKDLEGYHLRI------------------YIFDSVYSSVIG---DGEN 198
            .|::::  :.|..|   :.:|.||.:|:                  :||...|...:.   |..|
  Fly   168 TVIEETLVEQYISIRGSFNNLYGYPVRVAAYNNAPRSMLYVNRWGKHIFAGFYMRFLRAFIDARN 232

  Fly   199 ----KVLSVTGADAKLAKTVARQ-LNFTADFVWPDDEFF----GGRLANGEYSGGVGRAHRGEVD 254
                .||:.:.:.......:..: ::..||.:..:...|    |.|:|    |..|...|...:.
  Fly   233 GSFVPVLTPSNSPGNCTLNLVNETVDVCADALAANPAAFSLTHGFRIA----SANVLVTHAKPLH 293

  Fly   255 IIFAGFFIKDYLTTHIQFSAAVYMDELCLYVKKAQRIPQSILPLFAVHMDVWLCFLLVGLLGALV 319
            ..       .|||...|:|                               ||.|         ||
  Fly   294 SY-------RYLTAPFQWS-------------------------------VWAC---------LV 311

  Fly   320 WLILRAVNLILGIEGVPDGSRATRISYFGAARRIFVDTWVIWVRVNVGRFPPFHSERIFVASLCL 384
            ..:|..||.               :|:.|            |:|.....|..:..|   |.|..|
  Fly   312 IYVLLVVNF---------------LSFIG------------WLRSGKWEFSKYLLE---VFSSLL 346

  Fly   385 VS-------------VIFGALLESS----------LATVYIRPLYYRDVNTLRELDES 419
            .|             ::||.|..:.          |.::.|..::.:.::|...|.||
  Fly   347 FSGFYLKEIRGRERYILFGVLFIAGFVYSTEYLGLLKSMLISEVFEKQIDTFEALVES 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir100a	NP_651898.2	Periplasmic_Binding_Protein_Type_2	210..>255	CDD:304360	9/49 (18%)
Ir100a	NP_651898.2	Lig_chan	<439..580	CDD:278489
Ir48b	NP_610697.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100