DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir100a and Ir52c

DIOPT Version :9

Sequence 1:	NP_651898.2	Gene:	Ir100a / 43753	FlyBaseID:	FBgn0039879	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_725470.1	Gene:	Ir52c / 246630	FlyBaseID:	FBgn0050468	Length:	599	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	83/438 - (18%)
Similarity:	154/438 - (35%)	Gaps:	129/438 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LVQFLMQEKS--SIIISAKQEEVPSRAKIMRHHFFIFDGVHQMQEIRTSLFNTD---GFYILAL- 112
            |:|.|..|||  ::::..:...:||          :|:.: |:..:..|..:|:   .|..|.|
  Fly    36 LLQRLQVEKSYDTLLVYGEDCAIPS----------LFERL-QVPAVLVSSGSTNFDWNFSSLTLI 89

  Fly   113 -----ENNTIEDDVLLMEFAAD--VWLQHGHSR-----IYYVQLSKKSVLLFNPFLQRLVVVQDS 165
                 ::...|:...||:....  :.|..||.:     .:|.:..:.:|.:......:|.||
  Fly    90 LSCNFQDEREENYRTLMKLQTSRRLILLKGHIKPESVCDFYSKKEQHNVAMVKENFYQLEVV--- 151

  Fly   166 KTYS-RIYKDLEGYHLRIYIFD--SVYSS-----------VIGD--------------GENKVLS 202
              || |:::| :.|. ::.:||  |:|..           .:.|              ||.|...
  Fly   152 --YSCRLFQD-QNYE-KLNLFDGKSIYKDQFRNMHGAPIRTLSDKEPPRTIPYIDSKTGEEKFKG 212

  Fly   203 VTG-ADAKLAKTVARQLNFTADFVWPDDEFFGGRLANGEYSGGVGRAHRGEVDIIFAGFFIKDYL 266
            ..| ..::..|.|...:....|.:..|:|.                   ..|||  ..|...|.|
  Fly   213 YVGMLISQFVKKVNATMQIREDLIKDDEEV-------------------SFVDI--TNFTSNDIL 256

  Fly   267 TTHI---------QFSAAVY---MDELCLYVKKAQRIPQSILPLFAVHMDVWLCFLLVGLLGALV 319
            ...|         .:.|..|   |...|........:|.|         ||::..:...:|  ::
  Fly   257 DIGICEARTLEMSNYDAISYPYLMSSYCFMAPLPDSLPFS---------DVYMAIVAPSIL--IM 310

  Fly   320 WLILRAVNLILGIEGVPDGSRATRISYFGAARRIFVDTWVIWVRVNVGRFPPFHSERIFVASLCL 384
            :||:..:..:|.|.......|:..|      |.:.::.  |.:|..:.:..||..:......|..
  Fly   311 FLIIFCICSVLIIYIQERSYRSLTI------RSVLMND--ICLRGFLAQPFPFPRQYNRKLKLIF 367

  Fly   385 VSVIFGALLESSLATVYIRPLYYRDVNTLRELDESGQPIYIKHPAFKD 432
            :.|.|.:|:.:::.|.|::...:            |.||..:..:|.|
  Fly   368 MLVCFSSLISTTMYTAYLQAFLW------------GPPIEPRLTSFDD 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir100a	NP_651898.2	Periplasmic_Binding_Protein_Type_2	210..>255	CDD:304360	6/44 (14%)
Ir100a	NP_651898.2	Lig_chan	<439..580	CDD:278489
Ir52c	NP_725470.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100