Protein Alignment Acf and YPL216W

DIOPT Version :10

• Sequence 1: NP_536734.2
• Gene: Acf / 43751
• FlyBaseID: FBgn0027620
• Length: 1476
• Species: Drosophila melanogaster
• Sequence 2: NP_015108.1
• Gene: YPL216W / 855885
• SGDID: S000006137
• Length: 1102
• Species: Saccharomyces cerevisiae
• Alignment Length: 1055
• Identity: 203/1055 - (19%)
• Similarity: 366/1055 - (34%)
• Gaps: 329/1055 - (31%)

  Fly    33 TKRIFRDYEHYFRHVMVINSTVWQCEATGKENLTYEEAVKSERAARKKMEQF--KQSLRAPVLLV 95
            ::|| .||:...:.:......::.||.:||:.|:|.:|:|||...|:|:...  |:..:|    :
Yeast    32 SERI-NDYDSDLKKLDFYKRDIFTCEISGKDGLSYFKALKSEEQHREKVRYLLPKELRKA----I 91

  Fly    96 VEHAQQSAVNTLNMIVAKFLRK---RYFIGEEVSVQA-KKNATYTVLGVKLDKNMPEPLNGIYED 156
            ...|..|.:..:..:|....::   |:|||:.|.::. :|||..|                 |::
Yeast    92 ANFANFSPIRKVGHLVESAFQRFSNRFFIGDTVCLKTIQKNALIT-----------------YKE 139

  Fly   157 TD-NLVYRLRPNKGDPSAELDLPFRQLRRSRMEFNLENLSMFIKSNVSRVDGLLRPKPEAYKQYV 220
            .: |||       ..|:.|                 .|:::|:..:|.:.:|::    |:.|..:
Yeast   140 GEPNLV-------ESPTIE-----------------NNVTLFLVKDVFQSNGMM----ESEKGEI 176

  Fly   221 TDPGVNF-------------STIFIGKMPRYSPAKIKKPDGKKQSTLNKYIVAGEATAAKSKAKA 272
            :.|.::.             :.:.:|:      .:||:|    :|..:|:|:|........|...
Yeast   177 SAPKLSLYLITECLNRESKGAALIVGQ------NEIKRP----ESHFSKFIIACFLNEILIKVSN 231

  Fly   273 KSDAKSLAEELERVKREKEAKLIELEKQKAEKKA--QLIERVENECN---------LLLQKTDDL 326
            |..|.      .|||:|      .:|:.....|.  .:|:.:.:..|         |.:....|:
Yeast   232 KEHAP------WRVKQE------YIERYDVNPKCSPNMIDYLPDRMNSSSSELYTPLTIPPESDV 284

  Fly   327 ERTDQKVLPRYRQIVTLLPEHLLGDAFMMREFMHTYTGLLSGIEVFRQNLS-----FYEMTRALT 386
            |..|.|                     ...|...|....||.|:.....:|     .|:...:|.
Yeast   285 EPADWK---------------------ETSETSETSETSLSKIKAIDDEISVSFDHIYDNVNSLA 328

  Fly   387 AREIAGPLSDILLVLLGTVFDLQKEEEEECAVTYLDRAAQ----TQEPYWSMAQAAKSHL----- 442
            ..::.|.:.|..|...|.....:.       ::|||.:.:    .|:.:...:|.....|
Yeast   329 YNDLKGTVDDKELPFTGPSIPFEN-------ISYLDSSLEYKNIDQKWFKECSQFPTERLLVVYQ 386

  Fly   443 --------YAKRHFSF-----KVNELPLDALTLSEVLRLHLL----GSGAFVNEKA--ERWRVMY 488
                    ....||:|     .:.....:|| :.|.::::.|    ..|:|.|||.  |.:..:.
Yeast   387 FLSFFGRFIGLSHFNFDQFLTTIKCTSPEAL-VDEYVKINFLKTYNSKGSFTNEKPRNEIYNQVT 450

  Fly   489 RNGYSSKE----------------------------DPGLELRLEHSHILRILKNHSV----YQ- 520
            .:..|.:|                            |...|..:......:.|||..:    |:
Yeast   451 SSNVSQREKANVFNADESQRIPSNFTRNQKMRKFITDKSTEFVMYSIFKGKPLKNDDMEFQSYEK 515

  Fly   521 --LKFKDIMLLIRCLMSQIMTYSGTINLIEERMEQTAKARQDLRALVVGENKRLAAVEINRKKLT 583
              :.:.||:..:.|||:. .......||::...|:..|...:...:.:...|.|...:.:..||
Yeast   516 VNILYIDIVCSLMCLMTD-NEPDWNCNLMDNWTEEKRKEEGNKTEIDIAIEKCLNYGDTSWVKL- 578

  Fly   584 QMHHLEVN---------GVEPEKREAL----VEK-LKKSIAELHAQSDQQHRKHELQMLKLHSQL 634
             :|:...:         |:..:....:    |.| :.|.|..|           .:..:.|..:|
Yeast   579 -LHNKNFSNGNWLICLLGILQQNTHMIAYSDVAKCITKKILPL-----------SMNFVNLGDEL 631

  Fly   635 F-NFLVYLGMDRCYRKYYVLESMPGIFVEHSPDSLD----TC----LEQPITNKSQIEI-RQQSA 689
            : ||...|.:.......:||......|..:..:.:|    .|    |:.....|..|:: ||...
Yeast   632 WDNFRKRLSIKDKIDVLWVLVDFASNFSSYIKELVDKVPKLCNGIRLKLDSAKKEYIKLKRQLKT 696

  Fly   690 LPKNRKDLRVYL-LKLYGDDEKK-----TKKKAKHSLENKENQEHRLNGSAEPMDVESDSPEAPT 748
            |.|||..|...: :..||.||.|     .|.|..:.:|:....|.:|        ::||.
Yeast   697 LTKNRVKLHSNVSMNRYGSDECKGKVNALKVKIAYLMEDIAFLEAKL--------IQSDI----- 748

  Fly   749 HFELLMCSGDKRSCIVHDSRNGQRQRW--------AYIYKAEEIDE--LIKALNPN--------- 794
                      ||..|:...|||.|..|        |...|.||:..  .:....|:
Yeast   749 ----------KRLEILGKDRNGNRYYWMDSNGSSSAISEKNEELYNCCFLWVQGPSEADINFCLD 803

  Fly   795 ----GLREYELL-----------QELSVLRSLIEQHAKTCPVDLLSLENET---MRKKFMAAME- 840
                .|:::|||           :..|:.||....:.:....:...:.|..   ||....|.::
Yeast   804 VDVESLKKWELLAKAKGTAYATKEVFSIFRSTDGSYYQIAQGENFMIINSNGILMRPTIPAFIDK 868

  Fly   841 ---SETNRK----YGEANFGLPNGTDLNEVMRLH-LVDRIIQF-ENDIYTGDLGRLKVKDMEKWR 896
               |||..|    :.:..|       .|::..:| ||||:... ||:      |:||.....|
Yeast   869 KIISETPEKLLLSHHQWAF-------FNDIEDIHMLVDRLDDLRENE------GQLKKALTSK-- 918

  Fly   897 SDLLGGNYDAQCKLQ 911
            .|.:..:|..|.|::
Yeast   919 MDRIEVSYKQQFKIK 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:463140	25/96 (26%)
		DDT	346..411	CDD:214726	12/69 (17%)
		WSD	641..>666	CDD:464775	4/24 (17%)
		WSD	<774..805	CDD:464775	10/64 (16%)
		PHD_RSF1	1064..1109	CDD:277018
		PHD	1244..1284	CDD:214584
		Bromo_Acf1_like	1349..1463	CDD:99936
YPL216W	NP_015108.1	WAC_Acf1_DNA_bd	26..124	CDD:463140	25/96 (26%)
		DDT	375..435	CDD:214726	9/60 (15%)