DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acf and SPT7

DIOPT Version :9

Sequence 1:	NP_536734.2	Gene:	Acf / 43751	FlyBaseID:	FBgn0027620	Length:	1476	Species:	Drosophila melanogaster
Sequence 2:	NP_009637.1	Gene:	SPT7 / 852373	SGDID:	S000000285	Length:	1332	Species:	Saccharomyces cerevisiae

Alignment Length:	365	Identity:	81/365 - (22%)
Similarity:	138/365 - (37%)	Gaps:	116/365 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1136 VEEEDDEATDEEEEEKKDDDMT----DEDAEHENEKHDEDVEDDESVTSTP------SSSRV--- 1187
            |||:::|...:.|:.:..:.::    |||.:.|:|.:|||..|.::|...|      |||.:
Yeast   209 VEEKEEEEIGKNEKPQNKEGISKFAEDEDYDDEDENYDEDSTDVKNVDDPPKNLDSISSSNIEID 273

  Fly  1188 --NGRILRRPRTRPTSRRLTSKEIEE---------HAQEDVDSGDVSDDASLTAGEDTIEDESDE 1241
              ...:|....::.|..:|.:..:||         |:.| .|...:.....|        :|||
Yeast   274 DERRLVLNISISKETLSKLKTNNVEEIMGNWNKIYHSFE-YDKETMIKRLKL--------EESD- 328

  Fly  1242 EKVCQKCFYDGGEIKCVQCRLFFHLECVHLKRPPRTDFVCKTCKPMPQRPRRRHSNMNGDHDRDE 1306
             |:.:|     |:                 |:..|:|....|       ..:...|.|.:.|.::
Yeast   329 -KMIEK-----GK-----------------KKRSRSDLEAAT-------DEQDRENTNDEPDTNQ 363

  Fly  1307 EEPKA----------KRPRNSLRLSIDKTARPSNGNNNNNNNNSSVNNNNHRRSGRRTNEHMPLN 1361
            :.|..          |||:.|   ::|.|......|.:..:..||:         ::....:.::
Yeast   364 KLPTPEGSTFSDTGNKRPKQS---NLDLTVNLGIENLSLKHLLSSI---------QQKKSQLGIS 416

  Fly  1362 SAALYDLLEQIMKHKAAW------------------------------PFLRPVLTSEVPDYHQI 1396
            ...|..|:..:.|:::.|                              |||..|...|.|:||||
Yeast   417 DYELKHLIMDVRKNRSKWTSDERIGQEELYEACEKVVLELRNYTEHSTPFLNKVSKREAPNYHQI 481

  Fly  1397 IKTPMDLAKIKSKLNMGAYQLNEELLSDIQLVFRNCDLYN 1436
            ||..|||..:..||....|...:|.:.||.|:::||..||
Yeast   482 IKKSMDLNTVLKKLKSFQYDSKQEFVDDIMLIWKNCLTYN 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:287503
		DDT	346..411	CDD:214726
		WHIM1	505..554	CDD:292246
		WHIM2	637..666	CDD:292247
		WHIM3	775..813	CDD:292248
		PHD_RSF1	1064..1109	CDD:277018
		PHD	1244..1284	CDD:214584	5/39 (13%)
		Bromo_Acf1_like	1349..1463	CDD:99936	30/118 (25%)
SPT7	NP_009637.1	COG5076	282..680	CDD:227408	61/292 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810