Protein Alignment Acf and baz1b

DIOPT Version :10

• Sequence 1: NP_536734.2
• Gene: Acf / 43751
• FlyBaseID: FBgn0027620
• Length: 1476
• Species: Drosophila melanogaster
• Sequence 2: NP_001334601.2
• Gene: baz1b / 571727
• ZFINID: ZDB-GENE-010328-16
• Length: 1802
• Species: Danio rerio
• Alignment Length: 1834
• Identity: 334/1834 - (18%)
• Similarity: 601/1834 - (32%)
• Gaps: 713/1834 - (38%)

  Fly     2 PICKREGF----DLNQKEGKNETFHDNDQVFCCYITKRIFRDYEHYFRHVMVINSTVWQCEATGK 62
            |:..|:.:    .|::..|..|      :|:....||..||:.|.|...:......:|.|::||.
Zfish     3 PLLGRKPYPLVKPLSEPPGPGE------EVYTIEHTKEAFRNKEEYEARLRRYGERIWTCKSTGS 61

  Fly    63 ENLTYEEAVKSERAARKKM-EQFKQSLRAPVLLVVEHAQQSAVNTLNMIVAKFLRKRYFIGEEVS 126
            ..||::||.:.|:...:.: |::......|||.:|.|........::.:..:.|.| |.:||:..
Zfish    62 SQLTHKEAWEEEQEVTELLQEEYPVWFEKPVLEIVHHNTVPLDKLVDQVWVEILTK-YAVGEKCD 125

  Fly   127 VQAKKNATYTVLGVKL-------DKNMPEPLNGIYE----DTDN--------------------- 159
            :....:.|.:|..||:       ::|..:.:.|..:    |.:|
Zfish   126 LMVGNDKTLSVEVVKIHPLENPPEENAEKKMEGACDSPSSDKENASQENLKKEPQSKEEESRRES 190

  Fly   160 -----------------------LVYRLRPNKGD------PSAELDLPFRQLRRSRMEFNLENLS 195
                                   ::.:..|:|.|      .....|:|...|.|:....|.|.:.
Zfish   191 LSDRARRSPRKLPTTMKEEKKKWVMPKFLPHKYDVKLVNEDKVISDVPADNLYRTERPPNKEIMR 255

  Fly   196 MFIKSNVSRV-----------DGLLR--PKPEAYKQYVTD----------------------PGV 225
            .||:....|:           |.|::  ..|..:..::.|                      |..
Zfish   256 YFIRHYALRLGSGESAPWVVEDELVKKFSLPSKFSDFLLDPHKFLAENPSTKRKSLSSPEGKPRK 320

  Fly   226 NFSTIFIG-------------------------------KMPRYSPAKIKK-------------- 245
            ...|:..|                               |....||.|:|.
Zfish   321 RLKTVETGTGGEGAKGDKKKNKDSQNIPLSPTIWSHMQVKKVNGSPLKMKNSGTSKKSDEENVLG 385

  Fly   246 ---------------PDGKKQSTLNKY-----------------------------IVAGEATAA 266
                           |..:::|.|||.                             :....|.|.
Zfish   386 TPKSSKKQGDKKSSDPKRRRKSGLNKTPNSQRLSKKEDKSLGGAKKPRMKQMTLLDLAKSPAAAG 450

  Fly   267 KSKA------------------------------KAKSDAKS-----LAEELERVKREKEAKLIE 296
            ..|.                              |.|.|.|:     |::..:.:..|..::|.|
Zfish   451 SPKKQRRSSTTGSTKLGKPFPPMALHLLRFYKENKGKEDKKTTLSSLLSKAAKALSPEDRSRLPE 515

  Fly   297 LEKQKAEKKAQLIER--------VENECNLLLQKTDDLER------------------------T 329
            ..|:..:|:.:|:|:        .|.:.::|.||..::::                        .
Zfish   516 ELKELVQKRWELLEQKRRWALMSEEEKQSVLKQKRQEVKQKLREKAKERREKEMQVRREMSRRYE 580

  Fly   330 DQ----KVLPRYR--QIVTLLPEHLLGDAFMMREFMHTYTGLLSGIEVFRQNLSFYEMTRALTAR 388
            ||    |.||.:|  .:...||..:.||..|:.||:|.|:|||...:.       |.:|......
Zfish   581 DQELEGKNLPAFRLFDMPEGLPNTIFGDVAMVVEFLHCYSGLLMPDDQ-------YPITSIALLE 638

  Fly   389 EIAGP------LSDILLVLLGTVFDLQKEEEEECAVTYLDRAAQTQEPYWSMAQAAKSHLYAKRH 447
            .:||.      |:.:|:|||.|:.      ::|.|..|.:
Zfish   639 ALAGEKAGFLYLNRVLVVLLQTLL------QDELAEGYSE------------------------- 672

  Fly   448 FSFKVNELPLDALTLSEVLRLHLLGSGAFVNEKA---ERWRVMYRNGYSSKEDPGLELRLEHSHI 509
            ....::|:||...::||::||.|..|.|...|.|   :.|    ::|....:       :..|..
Zfish   673 LDMPLSEIPLTMHSVSELVRLCLRPSDAHEEESARGSDDW----QSGADFDD-------MVSSEF 726

  Fly   510 LRILKNHSVYQLKFKDIMLLIRCLMSQI-MTYS----------GTINLIEERMEQTAKARQDLRA 563
            |..|:...|::|..::.:.|:..|..:| ||||          .:..:.:||:....:|....||
Zfish   727 LEKLETAEVFELDPQEKVSLLLALCHRILMTYSVEDHVEAVHQKSAEMWKERVATLKEANDRKRA 791

  Fly   564 -----------------LVVGENKRLAAVEINRKKLTQMHHLEVNGVEPEKREALVEKLKKSIAE 611
                             |:..|.|:.:.|:....|:     |.....|||...:.|:..:....:
Zfish   792 EKQKRKEQMETKTDGDVLIKAEKKKESTVKKETPKV-----LPKEEPEPEDMISTVKSRRLMSIQ 851

  Fly   612 LHAQSDQQHRKHELQMLK----------------------LHSQLFNFLVYLGMDRCYRKYYVL- 653
            ...:.::|.|.::::|.|                      ..::|......||.||.:.:|::.
Zfish   852 AKKEKEEQERLNKVRMEKEAEEERIRRQKAATEKAFQDAVTKAKLVLRRTPLGTDRNHNRYWLFS 916

  Fly   654 ESMPGIFVEHS--PDSLDTCL-----EQPITNKSQIEIRQQSALPKNRKDLRVYLLKLYGDDEKK 711
            :.:||:::|..  .:|:|...     |:|:..:.:                         ::|::
Zfish   917 DVVPGLYIEKGWVHESIDYSFTLPPEEEPVLTEEE-------------------------EEEEE 956

  Fly   712 TKKKAKHSLENKENQEHRLNGSAEPMDVESDSPEAPTHFELLMCSGDKRSCIVHDSRNGQRQRWA 776
            .||:     |..|:.|....||......:.....||:|...:..:..|:         || ..|.
Zfish   957 VKKE-----EETEDGEKEDEGSIISASNDISQQGAPSHESSIETTVPKQ---------GQ-NLWF 1006

  Fly   777 YIYKAEEIDELIKALNPNGLREYELLQELSVLRSLIEQHAKTCPVDLLSLENETMRKKFMAAMES 841
            .....::.|||:::|:|.|:||.||...|.:
Zfish  1007 VCDTPKDFDELLESLHPQGVRESELKIRLQI---------------------------------- 1037

  Fly   842 ETNRKYGEANFGLPNGTDLNEVMR-LHLVDRIIQFENDIYTGDLGRLKVKD-----MEKWRSDLL 900
                             :..|::. :||..:          |:.| ||..|     ::..|||::
Zfish  1038 -----------------NYQEILHSIHLTKK----------GNPG-LKTCDGHQELLKFLRSDII 1074

  Fly   901 GGNYDAQCKLQWGPGGKLEDEAGSDNESHETHEEDDGALLGKYARKPYRDPGMYLAASADTKPLP 965
                :...:||.|..|.||     |....|..||....|                      :.||
Zfish  1075 ----EVASRLQKGGLGYLE-----DTSEFEEFEERVKTL----------------------EKLP 1108

  Fly   966 DSDDEEDQHTNAVSIPIAVHNMASALLQVEQAIGKRFLKEPYGMKKWDPKQ-------------E 1017
            :                    ....::.:::::.|:||:.....|:...|:             :
Zfish  1109 E--------------------FGECVIALQESVIKKFLQGFMAPKQKKKKKTGGEESTTAEEVDD 1153

  Fly  1018 ALKLACDSR----LHQWEVSLMESTSFAQVFLHLNILHDCIQWRRSTNKSLCKVCRRGSDPEKML 1078
            ..|||.::|    :.:|:.::.|:.:|:::.:.|.:|..||:|..|...:.||||||..:.:|::
Zfish  1154 QKKLAEEARVATAVEKWKTAVREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRRKGEDDKLI 1218

  Fly  1079 LCDECNAGTHMFCLKPKLRSVPPGNWYCNDCVKSLG--LSNGQNEKDKKQATKKKRKFIVEEEDD 1141
            ||||||...|:|||:|.|..:|.|.|.|..|..::.  .|.|:|.|:..:          ||||.
Zfish  1219 LCDECNKAFHLFCLRPALYRIPAGEWLCPACQPTIARRSSRGRNYKEDSE----------EEEDS 1273

  Fly  1142 EATDEEEEEKKDDDMTDEDAEHENEKHDEDVEDDESVTSTPSSSRVNGRILRRPRTRPTSRRLTS 1206
            |..||||.|::     |.:.||.|..|.                     :..|.:.:.:|:....
Zfish  1274 EEEDEEESEEE-----DSEEEHRNTGHS---------------------LRSRKKVKTSSKSKMQ 1312

  Fly  1207 KEIEEHAQEDVDSGDVSDDASLTAGEDTIEDESDEEKVCQKCFYDGGEIKCVQCRLFFHLECVHL 1271
            |
Zfish  1313 K---------------------------------------------------------------- 1313

  Fly  1272 KRPPRTDFVCKTCKPMPQRPRRRHSNMNGDHDRDEEEPKAKRPRNSLRLSIDKTARPSNGNNNNN 1336
                      |..||..:...:..:|.:....:...:||: |...|..:.||:..
Zfish  1314 ----------KPAKPASRSASKTDTNPSKTSPKSSAKPKS-RAAPSSPVDIDELV---------- 1357

  Fly  1337 NNNSSVNNNNHRRSGRRTNEHMPLNSAALYDLLEQIMKHKAAWPFLRPVLTSEVPDYHQIIKTPM 1401
                       |:|.:..:....:......::|::|||.:.:|||..||...|..||..:|.:||
Zfish  1358 -----------RQSSKPPSRKKDVELQKCEEILQKIMKFRHSWPFREPVSAEEAEDYQDVITSPM 1411

  Fly  1402 DLAKIKSKLNMGAYQLNEELLSDIQLVFRNCDLYNVEGNEIYDAGCQLERFVID----------- 1455
            ||..::.|.....|....:.:.|::|:|.|.:.||...:.:.....:.|...::
Zfish  1412 DLTTMQGKFKSSEYHSASDFIEDMKLIFSNAEEYNQPSSNVLTCMSRTEEAFVELLQKSLPGVSY 1476

  Fly  1456 -RCRDMQLPFRPSD 1468
             |.|..:....|||
Zfish  1477 LRRRTRKRAATPSD 1490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:463140	27/99 (27%)
		DDT	346..411	CDD:214726	20/70 (29%)
		WSD	641..>666	CDD:464775	8/27 (30%)
		WSD	<774..805	CDD:464775	11/30 (37%)
		PHD_RSF1	1064..1109	CDD:277018	23/44 (52%)
		PHD	1244..1284	CDD:214584	1/39 (3%)
		Bromo_Acf1_like	1349..1463	CDD:99936	29/125 (23%)
baz1b	NP_001334601.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..207		4/62 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..470		16/165 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	557..579		0/21 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	785..839		12/58 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	940..973		8/62 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1256..1371		34/246 (14%)