Protein Alignment Acf and baz2ba

DIOPT Version :10

• Sequence 1: NP_536734.2
• Gene: Acf / 43751
• FlyBaseID: FBgn0027620
• Length: 1476
• Species: Drosophila melanogaster
• Sequence 2: XP_021332704.2
• Gene: baz2ba / 561095
• ZFINID: ZDB-GENE-070615-37
• Length: 2318
• Species: Danio rerio
• Alignment Length: 1487
• Identity: 287/1487 - (19%)
• Similarity: 494/1487 - (33%)
• Gaps: 570/1487 - (38%)

  Fly   275 DAKSLAEELERVKREKEAKLIELEKQKAEKKAQLIERVENECNLLLQK-TDDLERTDQKVLPRYR 338
            :|:..|||.||:::||..     ||:..:::...:.|:|.|....::| .:|:..||.|.||...
Zfish  1096 EARKKAEERERLRQEKRD-----EKRLNKERKMELRRLELEMIREMKKPNEDMCLTDHKPLPGVP 1155

  Fly   339 QIVTL-LPEHLLGDAFMMREFMHTYTGLLSGIE--------VFRQNLSFYEMTRALTAREIAGPL 394
            :|..| ||..:..|..|:.:|:.:: |.:.|::        :.::.|        |......|.:
Zfish  1156 RIPGLVLPGSVFSDCLMVVQFLRSF-GKVLGLDSSELPTLGILQEGL--------LNLGNSMGQV 1211

  Fly   395 SDILLVLLG----------------------TVFDLQKEEEEECAVTYLD-RAAQTQEPYWSMA- 435
            .|:|:.||.                      |...|.::...|....|:: ..:||.....:::
Zfish  1212 QDLLVRLLSSAVSDPGLPQGHRAKSILGDHLTNVGLNRDNVSEVLQLYMEAHCSQTDLADLTLSL 1276

  Fly   436 --QAAKSHLYAKRH--FSFKVNELPLDALTLSEVLRLHLLGSGAFVNEKAERWRVMYRNGYSSKE 496
              :|.::|..|::.  .:|.||||......:||:
Zfish  1277 RTKAFQAHTPAQKASVLAFLVNELSCSKSVVSEI------------------------------- 1310

  Fly   497 DPGLELRLEHSHILRILKNHSVYQLKFKDIMLLIRCLMSQIMTYSGTINLIEERMEQTAKARQDL 561
                :..|||.::||  |:..:.:.|.|.:..:.                        ||.....
Zfish  1311 ----DKSLEHMNVLR--KDECIVEGKLKKMKTIY------------------------AKRTGKR 1345

  Fly   562 RALVVGENKRLA---AVEINRKKLT----QMHHLEVNGVEPEKREALVEKLKK------------ 607
            .::..||....|   |:...||:..    .....:.:..|.|..|...|:.||
Zfish  1346 ESMTGGEEPHAAGGSAIGHKRKRKAGDSDDDDDEDEDSDEDEDEEEEEEETKKGRRVETCDEDEG 1410

  Fly   608 ----SIAELHAQSDQQHRKHELQMLKL--HSQLFNFLVYLGMDRCYRKYYVLESMPGIFVE--HS 664
                |:.||..|.::..::..|...||  .|.....:.| |.||..|:|::|....|:::|  .|
Zfish  1411 DPATSVEELEKQIEKISKQQNLIRRKLFESSHALRSMSY-GQDRFRRRYWILPQCGGVYIEALES 1474

  Fly   665 PDSLDTCLE---QPITNKSQIEIRQQSALPK-------NRKDLRVYLLKLYGDDEKKTKKKAKHS 719
            .:.|:. ||   :.:.|...::::::   ||       ..::::..|     .:|.|.:::....
Zfish  1475 GEGLEE-LEKERERLRNCPVVQVKEE---PKEEVLQHHQHEEIQGTL-----KEEVKQEEEKPMD 1530

  Fly   720 LENKENQEHRLNGSAEPMDVESDSPEAPTHFELLMCSGDKRSCIVHDSRNGQRQRWAYI------ 778
            |:.:.|:|.|.:...:..||.:..|:.|   ||.:....:.....|..|:......|.|
Zfish  1531 LDQEPNKEARSSPLKDKTDVVATPPQLP---ELRLSQSPQCQEPPHTPRHAHNGCSATIAMDMTS 1592

  Fly   779 ----YKAEEIDELIKALNPNG--------------------LREYELLQELSVLRSLIEQHA--- 816
                ..:....:|.:|.:||.                    |.:.:||....:.:.|.|:..
Zfish  1593 GSSPAHSPTTSKLTEASSPNAEHAIPPPLQLGIPAHLLQPQLAQTQLLASDQLYKVLSERSGHWF 1657

  Fly   817 ---KTCPVDLLSL------------ENET-MRKKF---------------MAAMESETNR----- 845
               ...|.|..||            .|.| .|.|.               ::|..|..|.
Zfish  1658 SLLPRSPCDDTSLIQPSAHPQSSPKSNATNTRPKSPPPPSTSSPHHHLLPLSASASPLNPTAAAG 1722

  Fly   846 --------KYGEANFGLP------------------------------------------NGTDL 860
                    |.|.|..|||                                          :|:.:
Zfish  1723 ISNLSVQVKPGAALVGLPLYSWSGGVISPNLPLCSSPLHMYPSVEGSASPLLAPSVSTSKSGSPV 1787

  Fly   861 N--------------EVMRLHLVDRIIQFENDIYTGDLGRLKVKDMEKWR--------------- 896
            .              ::.|.|.:...:....|:.   ||..||.|||:.:
Zfish  1788 PTAEKLASAPSPVALDLPRNHDLPEPMAIPEDML---LGWWKVTDMEELKALVNSLHSRGIRERA 1849

  Fly   897 ---------------------------SDLLGGNYDAQCKLQWGPGGKLEDEAGSDNESHETHEE 934
                                       |:|..|....:...:|    .:|::|          .|
Zfish  1850 LQKQLQKSMELIVQTCNKNREVAVMEVSELDEGQVSVETLQEW----CVEEQA----------ME 1900

  Fly   935 DDGALL---GKYARK-----------PYRDPG------MYLAASADTKPLP------DSDDEEDQ 973
            .|.|||   .:..||           .|.:|.      :|.    :.||||      :|.:|...
Zfish  1901 TDIALLQQVEELERKVTSASLQVKGWTYPEPQSEREDLVYF----EHKPLPKHRPGAESQEERSS 1961

  Fly   974 HTNAVSIP-----IAVHNMASALLQVEQAIGKRFLKEPYGMK---KWD-----------PKQEA- 1018
            ....:..|     |||..:|    ::|:.|.:|:|:.|.|..   |.|           |...|
Zfish  1962 EKGLIRRPSNPLDIAVMRLA----ELERHIERRYLRSPLGTTIQIKLDNVGTVTVPAPAPSTSAG 2022

  Fly  1019 -----LKLACDSRLHQWEVSLMESTSFAQVFLHLNILHDCIQWRRSTNKSLCKVCRRGSDPEKML 1078
                 .::|...:|  |..:|.|..|.:|:.:.|..|...|.|.:|..|..|::||:|.:.:.:|
Zfish  2023 GEGGEEEIAPGMKL--WRKALSEVRSSSQLAMCLQQLQKSIAWEKSIMKVYCQICRKGDNEDLLL 2085

  Fly  1079 LCDECNAGTHMFCLKPKLRSVPPGNWYCNDCVKSLGLSNGQNEKDKKQATKKKRKFIVEEEDDEA 1143
            |||.|:.|.|.:|.|||:.::|.|:|||.||:..   ::||:.|.|.:...:
Zfish  2086 LCDGCDKGCHTYCHKPKITTIPEGDWYCPDCISK---ASGQSPKSKSKTPNR------------- 2134

  Fly  1144 TDEEEEEKKDDDMTDEDAEHENEKHDEDVEDDESVTSTPSSSRVNGRILRRPRTRPTSRRLTSKE 1208
            |......||     ..:|..:::|..|..|::|:.:||.|                |.::.|:.
Zfish  2135 TAPASGGKK-----TAEAAKKSKKQAETGEEEEATSSTNS----------------TPKKATAA- 2177

  Fly  1209 IEEHAQEDVDSGDVSDDASLTAGEDTIEDESDEEKVCQKCFYDGGEIKCVQCRLFFHLECVHLKR 1273
                                                                             
Zfish  2178 ----------------------------------------------------------------- 2177

  Fly  1274 PPRTDFVCKTCKPMPQRPRRRHSNMNGDHDRDEEEPKAKRPRNSLRLSIDKTARPSNGNNNNNNN 1338
                                  |:.|..:........|.:|.:...:...||||    :||.:..
Zfish  2178 ----------------------SSQNKKNSASTPNQMAPKPDSPACVKRAKTAR----DNNRDLG 2216

  Fly  1339 NSSVNNNNHRRSGRRTNEHMPLNSAALYDLLEQIMKHKAAWPFLRPVLTSEVPDYHQIIKTPMDL 1403
            ...:                         ||.::.:|:.|||||.||....||.|.::||.|||.
Zfish  2217 LCRI-------------------------LLAELERHQDAWPFLNPVNLKSVPGYRKVIKKPMDF 2256

  Fly  1404 AKIKSKLNMGAYQLNEELLSDIQLVFRNCDLYNVEGNEIYDAGCQLERFVIDRCRDM 1460
            :.|:.||....||..|..:.|:.|||.||:.:|.:.::|..||..:.:|...|..::
Zfish  2257 STIREKLVSSQYQNLETFIIDVNLVFDNCEKFNEDNSDIGRAGHNMRKFFEKRWTEL 2313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:463140
		DDT	346..411	CDD:214726	14/94 (15%)
		WSD	641..>666	CDD:464775	9/26 (35%)
		WSD	<774..805	CDD:464775	9/60 (15%)
		PHD_RSF1	1064..1109	CDD:277018	20/44 (45%)
		PHD	1244..1284	CDD:214584	0/39 (0%)
		Bromo_Acf1_like	1349..1463	CDD:99936	36/112 (32%)
baz2ba	XP_021332704.2	None