Protein Alignment Acf and baz2a

DIOPT Version :10

• Sequence 1: NP_536734.2
• Gene: Acf / 43751
• FlyBaseID: FBgn0027620
• Length: 1476
• Species: Drosophila melanogaster
• Sequence 2: NP_001307060.1
• Gene: baz2a / 450079
• ZFINID: ZDB-GENE-041010-202
• Length: 2460
• Species: Danio rerio
• Alignment Length: 1664
• Identity: 340/1664 - (20%)
• Similarity: 550/1664 - (33%)
• Gaps: 684/1664 - (41%)

  Fly    62 KENLTYEEAVKSERAARKKMEQFKQSLRAPVLLVVEHAQQSAVNTLNMIVAKFLRKRYFIGEEVS 126
            ||:||.||        ::|:.:.|:.::..                    |:..||.....:::.
Zfish  1202 KEDLTEEE--------KEKLAKIKKKMKRK--------------------ARMKRKEDAKNKKMR 1238

  Fly   127 VQAKKNATYTVLGVKLDKNMPEPLNGIYEDTDNLVYRLRPNKGDPSAELDLPFRQLRRSRMEFNL 191
            ::.:|        .||:|:..:.|       ||         ||    |.|||.|..
Zfish  1239 LEKRK--------AKLEKSKEQGL-------DN---------GD----LSLPFSQSS-------- 1267

  Fly   192 ENLSMFIKSNVSRVDGLLRPKPEAYKQYVTDPGVNFSTIFIGKMPRYSPAKIKKPDGKKQSTLNK 256
                   :|.:|..:|   ||....::.|..|.                |:...|:
Zfish  1268 -------ESTLSASEG---PKKPGRRRKVVVPA----------------AETFDPE--------- 1297

  Fly   257 YIVAGEATAAKSKAKAKSDAKSLAEELERVKREKEAKLIELEKQKAEKKAQLIERVE--NECNLL 319
                 :|:..|:.|:|:|.||:||:  .:.:.|.||:.....|:.||::||...|:|  .:..:|
Zfish  1298 -----QASPIKTVARARSKAKALAK--AQAQAEAEARAALAAKRAAERRAQAQRRMEERKKQQML 1355

  Fly   320 LQK----TDDLERTDQKVLPRYRQIVTLLPEHLLGDAF----MMREFMHTYTGLLSGIEVFRQNL 376
            |::    .:|:...|...||...:|..|   .|.|.||    .:.||:|.| |.:.|::|.:...
Zfish  1356 LEEMKKPAEDMCLPDHTPLPPLTRIPGL---KLSGLAFSNCLRVVEFLHGY-GKILGLQVPKDIP 1416

  Fly   377 SFYEMTRALTAREIA-GPLSDILLVLLGTVFDLQKEEEEECAVTYLDRAAQTQEPYWSMAQAAKS 440
            |...:...|...|.: |.|.|:|:.|:            |.|:         .:|      ...|
Zfish  1417 SLITLQEGLLGMEKSQGELLDLLIKLV------------ESAL---------HDP------GLPS 1454

  Fly   441 HLYAKRHFSFKVNELPLDALTLSEVLRLHLLGSGAFVNEKAERWRVMYRNGYSSKEDPGLELRLE 505
            :..:.:....|:.:|.|:..|:|||||:.|                         |..|.|:.:.
Zfish  1455 YYQSVKILGEKLVDLELNHSTVSEVLRVFL-------------------------EAHGFEMEVC 1494

  Fly   506 HSHILRILKNHSVYQLKFKDIMLLIRCLMSQIMTYSGTINL-IEERMEQTAKARQD--------- 560
            :|     |:..|...|| .|:...|...:.:.:..|..:.. |:..:|..|..|::
Zfish  1495 NS-----LRTKSFQTLK-PDVKASILAFVVEELNASNIVTREIDNTLENMATYRKNKWIIEGKLR 1553

  Fly   561 -LRA------------LVVGENKRLAAVEI-NRKKLTQMHHLEVNGVEPEKREALVEKLKK---- 607
             |:|            ||..|.:|.|.|.: ..:.:.:...||.......|.|....:::.
Zfish  1554 KLKAALVRKTGRPEEELVFEERRRSARVGVAEEESIEESCVLERGSRRKAKEEPKHTEIESPNTC 1618

  Fly   608 SIAELHAQSDQQHRKHELQMLKLHSQLFNF-LVYLGMDRCYRKYYVLESMPGIFVEHSPDSLD-- 669
            |:|||..|.|:..::......||.....:. .|.||.||..|:|.:|..|..|.||.:.|.|.
Zfish  1619 SVAELERQIDKLTKRQVFFRKKLQQSSHSMRAVSLGQDRYRRRYLLLPYMGCILVEGAEDILASG 1683

  Fly   670 --TCLEQPIT----------------------------NKSQIEIRQQSALP------------- 691
              |..::|:|                            ..|::.:....|||
Zfish  1684 EVTVTDEPVTYVKVITPAKAEVKAEPPLSPGFCTSSSPQGSRLSLTDLDALPGEASLMSTPRGRG 1748

  Fly   692 ----------------KNRK-------------------DLRVYLLKL----------------- 704
                            |||:                   ||.:..|:.
Zfish  1749 RPRKIKPEVELHLRTAKNRRRRRSSRSAGEDSGLSSPLQDLPLPALQASVKQPQDDEADASAPIV 1813

  Fly   705 -----YGDDEKKTKKKAKHSLENKEN----------QEHRLNGSAEPMDVESDSPEAPTHFELLM 754
                 .|:|..:.:...:...|.:..          .|..|:...|.....:|...||.:.:||.
Zfish  1814 ASGAGQGEDNSQPEDSMREQAEKRGQWFNLLPKEPCDETSLSQPCENTPASADGAPAPVNGDLLT 1878

  Fly   755 C--------------------------------------------SGDKRSCIVHDSRNGQRQR- 774
            .                                            ||..|   || ||.|..:|
Zfish  1879 ADPAQPLKQEVTTEALPLTFPLPVSVPVPLSSSAPAPRGRRRRRGSGPSR---VH-SRTGTAKRR 1939

  Fly   775 -------------------------------WAYIYKAEEIDELIKALNPNGLREYELLQELSVL 808
                                           |.:|.:.||:..::.||:|.|:||..|.:.||
Zfish  1940 GRPPSKLFQEVQLKYFTQLVVRPIPLEMVKGWWWIREPEELTAILSALHPRGIREKMLHKHLS-- 2002

  Fly   809 RSLIEQHAKTC------PVDLLSLENETMRKKFMAAMESETNRKYGEANFGLPNGTDLNEVMRLH 867
             ..:|..|:.|      |:..:.:|:..       |::..:.:::.|.
Zfish  2003 -KHMEYLAEVCTRSVNDPIFQMKVEDGD-------ALQEVSKQEWQEQ----------------- 2042

  Fly   868 LVDRIIQFENDIYTGDLGRLK-VKDMEKWRSDLLGGNYDAQCKLQWGPGGKLEDEAGSDNESHE- 930
              :|::|.       |:..|: |:|:|:   .::|.  |.|.|:.. |..:.|.|||.::.:.:
Zfish  2043 --ERVLQL-------DISVLQWVEDLEQ---RVVGA--DLQLKVAI-PNAENETEAGQESSNTQF 2092

  Fly   931 ---THEEDDGALLGKYARKPYRDPGMYLAASADTKPLPDSDD----EEDQHTNAVSIP-----IA 983
               |..|.|..          |:...|.....|.:     ||    .:.:.::.:.:|     :|
Zfish  2093 QIFTPPEPDST----------REDLQYYEHEVDPR-----DDWIVKTKKEWSDLLRVPSNPLDLA 2142

  Fly   984 VHNMASALLQVEQAIGKRFLKEPYGMKKWD-------------PKQEALKLACDS-------RLH 1028
            :..:|:    :|:.|.:||||||.    |:             |..|.:.|...|       ||.
Zfish  2143 ILRLAN----LERNIERRFLKEPL----WNAADVVRLAPLTPPPGGEEVPLDAVSLESEITPRLR 2199

  Fly  1029 QWEVSLMESTSFAQVFLHLNILHDCIQWRRSTNKSLCKVCRRGSDPEKMLLCDECNAGTHMFCLK 1093
            .|...|....|.:|:.|.|..|...|.|.||..|..|:|||:|.|.|.:||||.|:.|.|||||:
Zfish  2200 TWRQGLDRCRSSSQLSLCLLQLEKAIAWERSIIKVTCQVCRKGDDDEYLLLCDGCDRGCHMFCLR 2264

  Fly  1094 PKLRSVPPGNWYCNDCV-KSLGLSNGQNEKDKKQATKKKRKFIVEEEDDEATDEEEEEKKDDDMT 1157
            ||:..||.|:|:|.:|| |..|.|.......::::..:||:.     .::::||||..::  .||
Zfish  2265 PKVLQVPDGDWFCPNCVAKKTGESPRSQRSSRQRSKVRKRRL-----GEDSSDEEEGFRR--SMT 2322

  Fly  1158 DEDAEHENEKHDEDVEDDESVTSTPSSSRVNGRILRRPRTRPTSRRLTSKEIEEHAQEDVDSGDV 1222
            ....|                |..||||..:..|....|.|.|:|.          |.|:
Zfish  2323 TRQKE----------------TPAPSSSSSSTSISPSKRRRMTTRN----------QPDL----- 2356

  Fly  1223 SDDASLTAGEDTIEDESDEEKVCQKCFYDGGEIKCVQCRLFFHLECVHLKRPPRTDFVCKTCKPM 1287
                                               ..|.:
Zfish  2357 -----------------------------------TYCEI------------------------- 2361

  Fly  1288 PQRPRRRHSNMNGDHDRDEEEPKAKRPRNSLRLSIDKTARPSNGNNNNNNNNSSVNNNNHRRSGR 1352
                                                                             
Zfish  2362 ----------------------------------------------------------------- 2361

  Fly  1353 RTNEHMPLNSAALYDLLEQIMKHKAAWPFLRPVLTSEVPDYHQIIKTPMDLAKIKSKLNMGAYQL 1417
                           :|.::..|..|||||.||....||.|.:|||.|||...::.:|..|.|..
Zfish  2362 ---------------ILMEMEAHSDAWPFLEPVNPRMVPGYRRIIKNPMDFLTMRERLLQGGYCS 2411

  Fly  1418 NEELLSDIQLVFRNCDLYNVEGNEIYDAGCQLERFVIDR 1456
            .||..:|.||||.||:|:|.:.:|:..||..:.||...|
Zfish  2412 CEEFAADAQLVFNNCELFNEDTSEVGQAGHAMRRFFESR 2450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:463140	11/62 (18%)
		DDT	346..411	CDD:214726	19/69 (28%)
		WSD	641..>666	CDD:464775	11/24 (46%)
		WSD	<774..805	CDD:464775	12/62 (19%)
		PHD_RSF1	1064..1109	CDD:277018	25/44 (57%)
		PHD	1244..1284	CDD:214584	1/39 (3%)
		Bromo_Acf1_like	1349..1463	CDD:99936	38/108 (35%)
baz2a	NP_001307060.1	PHA03247	<298..629	CDD:223021
		HAT_MBD	1049..1123	CDD:238691
		DDT	1389..1451	CDD:470652	20/89 (22%)
		WSD	1648..>1678	CDD:464775	12/29 (41%)
		WSD	<1971..2004	CDD:464775	13/35 (37%)
		PHD_BAZ2A	2235..2281	CDD:277099	25/45 (56%)
		Bromo_BAZ2A_B_like	2355..2451	CDD:99935	40/241 (17%)