Protein Alignment Acf and tou

DIOPT Version :10

• Sequence 1: NP_536734.2
• Gene: Acf / 43751
• FlyBaseID: FBgn0027620
• Length: 1476
• Species: Drosophila melanogaster
• Sequence 2: NP_001097270.1
• Gene: tou / 36241
• FlyBaseID: FBgn0033636
• Length: 3131
• Species: Drosophila melanogaster
• Alignment Length: 1890
• Identity: 342/1890 - (18%)
• Similarity: 586/1890 - (31%)
• Gaps: 656/1890 - (34%)

  Fly    11 LNQKEGKNETFHDNDQVFCC------YITKRIFRDYEHYFRHVMVINSTVWQCEATGKENLTYEE 69
            |.|.:|..||        |.      |:|....|.|:       .::....:.||       ||.
  Fly  1445 LRQIDGSLET--------CAQMRKEKYMTDMKVRKYK-------ALHMRKARIEA-------YER 1487

  Fly    70 AVKSERAARKKMEQFKQSLRAPVLLVVEHAQQSAVNTLNMIVAKFLRKRYFIGEEVSVQAKKNAT 134
            | ::||.|..:....:|.|.|..|...|.|:.:|                  .||.:..|..:..
  Fly  1488 A-QAEREAAMQALMAQQKLDAERLKAEEEAKAAA------------------AEEAAAAAGTDGE 1533

  Fly   135 YTVLGVKLDKNMPEPLNGIYEDTDNLVYRLRPNKGDPSAELDLPFRQLRRSRMEFNLENLSMFIK 199
            .|..|        .| ||           .:|..||.:.|
  Fly  1534 ATKGG--------SP-NG-----------EKPEDGDQNEE------------------------- 1553

  Fly   200 SNVSRVDGLLRPKPEAYKQYVTDPGVNFSTIFIGKMPRYSPAK-IKKPD-----GKKQSTLNKYI 258
                   |..:...:..:|.:...||      :.:....|||| |.:.|     .|:......|.
  Fly  1554 -------GAAKEPQQQQQQPMEVDGV------VDEASLVSPAKTIIQTDNSLTPSKQDMPTPTYQ 1605

  Fly   259 VAGEAT----------------AAKSKAK-------------AKSDAKSLAEELERVKREKEAKL 294
            :.|.:|                |.||.|:             ...|...|..|:..|:.:::.:
  Fly  1606 INGSSTPTTSGVTGGDMNVLLQAKKSGARNSINDEHHHDVSIIDDDLSDLDSEITNVEEDEDNR- 1669

  Fly   295 IELEKQKAEKKAQLIERVENECNLLLQKTDDLERTDQKVLPRYRQIVTLLPEHLLGDAFMMREFM 359
              |...:.:||...|.|....|...|:|:     |:|.....:.|           |.|..|.:.
  Fly  1670 --LSADELQKKLDKIVRASLNCKEALEKS-----TNQLRAACFGQ-----------DRFWRRYWK 1716

  Fly   360 HTYTG--LLSGIEVFRQNLSFY-----------------------------------EMTRALTA 387
            ....|  .:..:|..:.::..|                                   |:..::|.
  Fly  1717 LPKAGGIFIEALESAQNDICDYHEALEAMDDKKDANDEKENSENEKDVAAESSEQPMEVDESITK 1781

  Fly   388 REIAGPLSDILLVLLGTVFDLQKEEEEECAVTYL--------------DRAA------------- 425
            .|...|.||:.:.........|.||:::..||.:              |.||
  Fly  1782 LEDGVPASDVGMPESNQQNAHQDEEDDDDDVTEINKVEPEIVDLGDDDDDAAPPLPKIEPPRPEI 1846

  Fly   426 QTQEPYWSMAQAAKSHLYAKRHFSFKVNELPLDALTLSEVLRLHLLGSGAFVNEKAERWRVMYRN 490
            :.:.....|.....:.:..|..|..:: ::|    ::..:|....|.:....|..       ..|
  Fly  1847 KVKSEMELMGPPPTTMISTKTDFEAEI-KIP----SMPGILMPPTLNNNNTNNNN-------NNN 1899

  Fly   491 GYSS--KEDPGLELRLEHSHILRILKNHSVYQLKFKDIMLLIRCLMSQIMTYSGT---------- 543
            |..:  |.:.||.|..:.       :|.|...:|.:|:.....|::....:...|
  Fly  1900 GSDNCDKLETGLGLGQQQ-------QNFSQSVIKTEDVKKEDDCIIVSTSSVDDTPKWFSIVRRE 1957

  Fly   544 INLIEE-RMEQTAKARQDLRALVVGENKR----------------------LAAVEINRKKLTQM 585
            :.||.| ..|:.....|:|:.....:|..                      :...:::..||...
  Fly  1958 VPLISELPAEEGGVVGQELQISYANQNCSAQLQLQGHPWDLINNMQYYSIPMDECKVDTSKLGNE 2022

  Fly   586 HHLEVNGVEPEKREALVEKLKKSIAELHAQSDQQHRKHELQ------MLKLHSQLFNFLVYLGMD 644
            ....::|::.::..|.||:.|....|........||.||.:      .|||..::...:.....|
  Fly  2023 CIFSLSGLDEKQMLAKVEEYKAHKVESKNGLGSPHRHHETKDDEEQAKLKLDKEIDTEMETDADD 2087

  Fly   645 RCYR-KYYVLESMPGIFVEHSPDSLDTCLEQPITNKSQIEIRQQSALPKNRKDLRVYLLKLYGDD 708
            ...: |::.|.|      :..||: ...:.:....|.:||:|...||.      :.|.
  Fly  2088 LAGKEKFFRLRS------DVPPDT-GGGVSEGTDVKPKIELRLDEALS------QAYY------- 2132

  Fly   709 EKKTKKKAKHSLENKENQEHRLNGSAEPMDVE---SDSPEAPTHFELLMCSGDKRSCIVHDSRNG 770
                     |::.|......:   :..|:|:.   |.:|:.....|.:..:|....  ||.....
  Fly  2133 ---------HNIANMSLSSVQ---TYIPIDIPLPLSMTPDEHRLLEQVKLAGFPER--VHGVYVP 2183

  Fly   771 QRQR--WAYIYKAEEIDELIKALNPNGLREYELLQELS--------------------------- 806
            :|||  |..:...:::.:|:|.|||:||||.||.:.|.
  Fly  2184 RRQRYGWWQLDDEQKLRQLLKTLNPSGLRERELQENLQRFLGLEQPLGVNYKLKSDIDFPEEFLM 2248

  Fly   807 --------------VLRSLIEQHAKTCPVDLLSLENETMRKKFMAAMESET----NRKYGEANFG 853
                          |..:||||        |.|||:    |...|:|:.:.    ||.  |:...
  Fly  2249 PDKKGDWNPKVAKRVELALIEQ--------LESLED----KVASASMQLKNWQLPNRV--ESELT 2299

  Fly   854 LPNGTDLNEVMRLHLV----DRIIQFENDI-----------YTGDLGRLKVKDMEKWRSDLLGGN 903
            |.:..|:.|...:.::    :|||..|.:|           .|||.....:...:...:......
  Fly  2300 LDSQEDVTEEDFVSIIPMIRERIIDLEANIERRYLKPPLGSQTGDAHLAVIAQNQHTTTQTQNSA 2364

  Fly   904 YDAQCKLQWGPGGKLEDEAGSDNESHETHEEDDGALLGKYAR-KPYRDPGMYLAASA-------- 959
            ..|...||      ::.:......:.:..::..|:..|.... ..:.:..|.|||:|
  Fly  2365 SAAAYLLQ------MQQQQQQQQLAQQQQQQQQGSGAGNSLNPSSFNERTMALAAAAAASGPGNA 2423

  Fly   960 -------------------------DTKPLPDSDDEED-----------QHTNAVSIPIAVHNMA 988
                                     :..|..:.|.:.|           |..:|||.......:|
  Fly  2424 TGVANSAVVAGATPCESGSGEPNSGNASPASNCDSDRDEKVEQIPKGLVQWRDAVSRSHTTAQLA 2488

  Fly   989 SALLQVEQAIG-KRFLKEPYGMKKWDPKQE--ALKLACDSRLHQWE------------------- 1031
            .||..:|..:. .:.:.:.|..|....|::  |.|.|..|:..|.:
  Fly  2489 MALYVLESCVAWDKSIMKAYATKNKSSKKKSSAKKQATPSKKQQQKKNKKEQQLTPNGKESKSKS 2553

  Fly  1032 -VSLMESTSFAQVFLHLNIL---HDCI-------------------------------------- 1054
             ::..|:.:...:.::|..|   ..|:
  Fly  2554 AINKPENQAPLSIKINLKALAQNGQCLLKTKTPPILTKSPTASPSSHPNTSDSDSDFGKRTKKKS 2618

  Fly  1055 --QWRRSTN--------KSL--CKVCRRGSDPEKMLLCDECNAGTHMFCLKPKLRSVPPGNWYCN 1107
              :.|||.|        .||  |:.|..|.:.:|:||||.|:.|.|.:|.|||:.::|.|:|||.
  Fly  2619 GGKRRRSANNTNSSKYSNSLQNCQFCTSGENEDKLLLCDGCDKGYHTYCFKPKMDNIPDGDWYCY 2683

  Fly  1108 DCV-------------------------------------------------------------- 1110
            :||
  Fly  2684 ECVNKATNERKCIVCGGHRPSPVGKMIYCDLCPRAYHADCYIPPLLKVPRGKWYCHGCISRAPPP 2748

  Fly  1111 --KSLGLSNGQNEKDKKQATKKKRKFIVEEEDDEATDE-EEEEKKDDDMTDEDAEHE-------- 1164
              :|.|.::|.:.|.::...::.........|:..|.. |..:::...:...|:.|.
  Fly  2749 KKRSAGGTSGSSSKSRRDRDRESGGSAKRRSDNSKTPAMEHMQQQQMPLAGGDSHHHHHQQPPSL 2813

  Fly  1165 NEKHDEDVEDDESVTSTPSSSRVNGRILRRPRTRPTSRRLTSKEIEEHAQEDVDSGD------VS 1223
            |..|||.:....:...:|:.|.|:.               |:.:.:.||...||...      :.
  Fly  2814 NSSHDESMNSLPAAPLSPAHSVVSA---------------TNYDDQHHANNSVDGSSRFHAHLIP 2863

  Fly  1224 DDASLTAGEDTIEDESDEEKVCQKCF----------YDGGEIK--CVQCRLFFHLECVHLKR--- 1273
            ...:.||.  .:||......|....:          :..|.|.  .||..:.|........|
  Fly  2864 PSNNGTAA--LLEDVPGGANVMPGVYPVYTPVAAGNFSAGLINQAPVQPAMPFANVVAMSPRAVT 2926

  Fly  1274 PPRTDFVCKTCKPMPQRPRRRHSNMNGD------HDRDEEEPKAKRPRNSLRLSIDKTARPSNGN 1332
            |.||.....|..|.|..|......|...      |....:.|    |:......:...:.|:.|.
  Fly  2927 PTRTRTPTPTPAPTPPPPPPTPLLMQASPTATALHVNACQSP----PQQQHAQLMTMPSPPAIGV 2987

  Fly  1333 NNNNNNNSSVNNNNH-----------RRSGRRTNEHMPLNSAALYDLLEQIMKHKAAWPFLRPVL 1386
            ....|..|....|.|           .:..:...:.:....|....||.::..|:.:||||.||.
  Fly  2988 GTATNQMSPPPINIHAIQEAKEKLKQEKKEKHATKKLMKELAVCKTLLGEMELHEDSWPFLLPVN 3052

  Fly  1387 TSEVPDYHQIIKTPMDLAKIKSKLNMGAYQLNEELLSDIQLVFRNCDLYNVEGNEIYDAGCQLER 1451
            |.:.|.|.:||||||||:.||.||...:|:..|:...|::.:|.||:::|.:.:.:..||..:.:
  Fly  3053 TKQFPTYRKIIKTPMDLSTIKKKLQDLSYKTREDFCVDVRQIFDNCEMFNEDDSPVGKAGHGMRK 3117

  Fly  1452 FVIDR 1456
            |...|
  Fly  3118 FFESR 3122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:463140	21/104 (20%)
		DDT	346..411	CDD:214726	13/101 (13%)
		WSD	641..>666	CDD:464775	4/25 (16%)
		WSD	<774..805	CDD:464775	13/32 (41%)
		PHD_RSF1	1064..1109	CDD:277018	21/46 (46%)
		PHD	1244..1284	CDD:214584	10/54 (19%)
		Bromo_Acf1_like	1349..1463	CDD:99936	36/108 (33%)
tou	NP_001097270.1	HAT_MBD	953..1027	CDD:238691
		TPH	<1041..1228	CDD:464007
		PTZ00121	<1045..1681	CDD:173412	62/337 (18%)
		DDT	1255..1317	CDD:460696
		WSD	1700..>1726	CDD:464775	5/36 (14%)
		WSD	<2173..2222	CDD:464775	18/50 (36%)
		PHD_BAZ2A_like	2640..2685	CDD:277020	20/44 (45%)
		RanBP2-type Zn finger	2680..2698	CDD:275376	5/17 (29%)
		PHD	2695..2741	CDD:214584	0/45 (0%)
		Bromo_BAZ2A_B_like	3027..3123	CDD:99935	36/96 (38%)