Protein Alignment Acf and tou

DIOPT Version :10

• Sequence 1: NP_536734.2
• Gene: Acf / 43751
• FlyBaseID: FBgn0027620
• Length: 1476
• Species: Drosophila melanogaster
• Sequence 2: XP_061518766.1
• Gene: tou / 1277930
• VectorBaseID: AGAMI1_012683
• Length: 3696
• Species: Anopheles gambiae
• Alignment Length: 1325
• Identity: 226/1325 - (17%)
• Similarity: 395/1325 - (29%)
• Gaps: 566/1325 - (42%)

  Fly   535 SQIMTYSGTINLIEERMEQ----------TAKARQDLRALVVGENKRLAAVEINR------KKL- 582
            |.:::|...:.:||.:.|.          |..:...||.....:.|..:...:||      |:|
Mosquito  2534 SSVISYGSDVEMIEVKDEDSNNCAVRAPITPGSYLYLRNTDTKQEKEFSDQLLNRWFSIVDKELP 2598

  Fly   583 ---TQMHHLEVNGVEPEK--REALVEKLKKSIAELHAQSDQQHRKHELQMLKLHSQLFNFLVYLG 642
               |:.....:||..|..  |:.......:.|.::      |..:.::..   :.|.|:..:..|
Mosquito  2599 LSSTECPLPTINGSTPASLARQIFTNITCREICQI------QGNRWDIGN---NIQFFSVPLEKG 2654

  Fly   643 MDRCYRKYYVLESMPGIFVEHSPDSLDTCLEQPITNKSQIEIRQQSALPKNRKDLRVYLLKLYGD 707
            ::..:....:| ||.|:.        |..:.:.|..||:.|..|.|
Mosquito  2655 VEIHFPNESIL-SMSGLD--------DDEINEVIAKKSRPEPLQLS------------------- 2691

  Fly   708 DEKKTKKKAKHSLENKENQEH--RLNGSAEPMDVESDSPEAPTHFEL------------------ 752
            |.|...|  :.::|...:|.|  ::...||.|..|:..||...:|.|
Mosquito  2692 DMKPAFK--RETIEYSYSQHHPNQIRLRAEMMAEETADPEEYGNFSLPAYMTLTLSNLTAYVQCD 2754

  Fly   753 ----LMCSGDKRSCIVHDSRNGQRQR-------------WAYIYKAEEIDELIKALNPNGLREYE 800
                |..:.::...:....::|..|:             |..|...||::||||||||.|:||..
Mosquito  2755 QFQPLQMTPEEEKQLEDVKQHGAPQKTEPQVVPREFRYGWWKINDIEELNELIKALNPRGVRERL 2819

  Fly   801 LLQELSVLRSLIE----------QHAKTCPVDLLSLENETMRKKFMAAMESETNRKYGEANFGLP 855
            |.|  |:|.||.|          .|.:..|.                                 |
Mosquito  2820 LRQ--SLLESLAESVNLTTPHHVSHPRAAPP---------------------------------P 2849

  Fly   856 NGTDLNEVMRLHLVDRIIQFENDIYTGDLGRLKVKDMEKWRSDLLGGNYDAQCKLQWGPG----- 915
            ||                      |.         :.|.|.:              |.|.
Mosquito  2850 NG----------------------YI---------EPEAWNA--------------WNPSIARRV 2869

  Fly   916 --------GKLEDEAGSDNESHETHEEDDGALLGKYARKPYRDPGMYLAASADTK----PLPDSD 968
                    ..:||:..|                                ||...|    |..:.|
Mosquito  2870 EVALLDQIEAMEDKVAS--------------------------------ASMQVKGWQMPQREGD 2902

  Fly   969 DEEDQHTNAVSIPIAVHNMASALLQVEQAIGKRFLKEPYGMKKWDPKQEAL-------------- 1019
            .|     |.|...:.:..:...:|.:|.||.:|:||.|.|:...:.:...:
Mosquito  2903 SE-----NGVVEDVTIEMLRERILGLEAAIERRYLKPPLGINTTEAQMAVIAQQESHSNQNNVSN 2962

  Fly  1020 ------KLACDSRLHQ----WEVSLMESTSFAQVFLHLNILHDCIQW-----------------R 1057
                  ..|.|..|.:    |..::..|.:.||:.:.|.:|..|:.|                 :
Mosquito  2963 LSNCSNSSAEDENLPKGLLSWRDAVERSVTTAQLSMALYVLESCVAWDKSIMKAQCTKGGKNGSK 3027

  Fly  1058 RSTNKSL---------------------------------------------------------- 1064
            ::|:||.
Mosquito  3028 KATSKSSKKKSGGAAASANQQDSPASKKGTASNNNTTTSTTTTTSTTTTNISGSSWECSAMTAAT 3092

  Fly  1065 --------------------------------CKVCRRGSDPEKMLLCDECNAGTHMFCLKPKLR 1097
                                            |:.|:.|...:|:||||.|:.|.|.:|.||::.
Mosquito  3093 ETMNTGSSNAANGKPKKKTLSKSKLSSLLLQNCQFCQSGESEDKLLLCDGCDRGYHTYCFKPRMD 3157

  Fly  1098 SVPPGNWYCNDCV-KSLG-----LSNG-------------------------------------- 1118
            .:|.|:|||.:|. |:.|     :..|
Mosquito  3158 KIPDGDWYCFECKNKATGDRKCIVCGGLRPPPLGKMVYCELCPRAYHQDCYIPPMLKYPRGKWYC 3222

  Fly  1119 QNEKDKKQATKKKRKFIVEEEDDEATDEEEEEKKDDDMTDEDAEHENEKHDE----DVEDDESVT 1179
            ||...|....||.::    :..:..|:...:...:..:.....:..|..|::    .:....|:.
Mosquito  3223 QNCVAKAPPKKKPQR----KPKERTTNNSSQSLLNSSLNSSQNQSLNSSHEDIATTPLSPAHSIA 3283

  Fly  1180 ST------------PSSSRVNG-RILRRPRTRPTSRRL--TSKEIEEHAQED------------- 1216
            ||            |..|.|.| .:...|.|..||...  ..::.::|.|:.
Mosquito  3284 STSHEESSAPQHLQPPHSSVPGVPMPAAPATASTSSAYHHQLQQQQQHPQQPLPPPLHPQQYGGA 3348

  Fly  1217 --VDSGD-------VSDDASLTAGED--------------------------------------- 1233
              ||:.:       |.::.....|:.
Mosquito  3349 PLVDANNYAMCHPPVPNETMALYGQQQAQQLQQQQQQQQYYQQYYQQQQPSTSVGPALAPPAPPQ 3413

  Fly  1234 ----------------TIEDESDEEKVC--QKCFYDGGEIKCVQCRLFFHL----ECV--HLKRP 1274
                            |:|.|:..:.|.  :...|...|       .:.|.    ||.  ..:.|
Mosquito  3414 QPYYPTPVESSATSAATVEQEAQSDYVASGEAAQYSASE-------GYTHAQSTSECEPDQQESP 3471

  Fly  1275 PRTD--FVCKTCKPMP-------QRPRRRHSNMNG------DHDR-----------------DEE 1307
            ...|  ....:..|:|       ..|.....|..|      |.||                 :|.
Mosquito  3472 AEVDDQIEASSESPVPAAGGGEFYSPSSNAMNAAGSSTSYLDSDRTPGGQDGEEGSCGGDSSEEY 3536

  Fly  1308 EPKAKRPRNSLRLSIDKTARPSNGNNNNNNNNSSVNNNNHRRS--GRRTNEHMPLNSAALYDLLE 1370
            :|:....::||.|:...::..|:.:::.....|...:....|:  .::..:.:....|....:||
Mosquito  3537 QPRPSPVKDSLCLAGSSSSSSSSISDHQRKERSKERDEAKERAKQEKKATKRLLKELAVCKTILE 3601

  Fly  1371 QIMKHKAAWPFLRPVLTSEVPDYHQIIKTPMDLAKIKSKLNMGAYQLNEELLSDIQLVFRNCDLY 1435
            ::..|:.:||||.||.|.:.|.|.::||:||||:.||.:|....|:..|:.::|::.:|.||:::
Mosquito  3602 EMELHEDSWPFLLPVNTKQFPTYRKVIKSPMDLSTIKKRLQDLVYKSREDFIADVRQIFDNCEVF 3666

  Fly  1436 NVEGNEIYDAGCQLERFVIDRCRDM 1460
            |.:.:.:..||..:.:|...|..|:
Mosquito  3667 NEDDSPVGIAGHGMRKFFEQRWADL 3691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:463140
		DDT	346..411	CDD:214726
		WSD	641..>666	CDD:464775	5/24 (21%)
		WSD	<774..805	CDD:464775	17/43 (40%)
		PHD_RSF1	1064..1109	CDD:277018	19/134 (14%)
		PHD	1244..1284	CDD:214584	8/49 (16%)
		Bromo_Acf1_like	1349..1463	CDD:99936	35/114 (31%)
tou	XP_061518766.1	None