Protein Alignment Acf and baz1a

DIOPT Version :10

• Sequence 1: NP_536734.2
• Gene: Acf / 43751
• FlyBaseID: FBgn0027620
• Length: 1476
• Species: Drosophila melanogaster
• Sequence 2: XP_004917293.2
• Gene: baz1a / 100497377
• XenbaseID: XB-GENE-986582
• Length: 1587
• Species: Xenopus tropicalis
• Alignment Length: 1716
• Identity: 430/1716 - (25%)
• Similarity: 703/1716 - (40%)
• Gaps: 416/1716 - (24%)

  Fly     1 MPICKREGF-------DLNQKEGKNETFHDNDQVFCCYITKRIFRDYEHYFRHVMVINSTVWQCE 58
            ||:..|:.|       ||...|          ::|.|.:|..|||||:.:|...::.||.||.|.
 Frog    15 MPLLHRKPFIRQPPPPDLQPTE----------ELFYCRVTNEIFRDYDDFFERTILCNSLVWSCS 69

  Fly    59 ATGKENLTYEEAVKSERAARKKMEQFKQSLRAPVLLVVEHAQQSAVNTLNMIVAKFLRKRYFIGE 123
            .|||..|||:||::||:..|:.::.|.:||..|:|.:....::..|..|...:..:::.|:|:.|
 Frog    70 LTGKSGLTYQEALESEKKVRQSLKTFPESLIVPILYLSTLVRRQRVTDLCEEIFAYVKDRFFVDE 134

  Fly   124 EVSVQAKKNATY--TVLGVKLDKNMPEPLNGIYEDTDNLV------------------------- 161
            .|:|.....|..  .:|.|||........||...:.|.:|
 Frog   135 TVTVVRNSGARLECKILEVKLPPQQNGVANGHVSNEDTIVISDSDEEPPKEMPQTRKKKEPTNPS 199

  Fly   162 ---YRLRPNKGDPSAELDLPFRQLRRSRMEFNLENLSMFIKSNVSRVDGLLRPKPEAYKQYVTDP 223
               |:::|.:.:....:.:...||.|....|:.:.|.:|:|.:....:|:::.||.:..:|....
 Frog   200 LCKYKVKPIQKELYESVTVKGSQLSRKPSLFSQDRLKLFLKLHCEAHEGIIKTKPSSVTKYQVSV 264

  Fly   224 GVNFSTIFIGKMPRYSPAKIKKPDGKKQS---TLNKYIVAGEATAAKSK---------------- 269
            . ||...|    |...|...:.|..||.|   ..||::..|...|.|.|
 Frog   265 R-NFLNYF----PEEPPDFQRSPPNKKISGRPLPNKHLNRGNGLANKQKQIQAAKERERILQQKK 324

  Fly   270 -------------------AKAKSDAKSLAE----------ELERVKREKEAKLIELEKQK---- 301
                               |:::...|.:.|          |:||:|:::|.:.::|||:|
 Frog   325 QLKAMEMEKARMRRERAVDARSRIQEKHIKERQKEELKKIVEVERLKKKEEKERMKLEKEKEREK 389

  Fly   302 -AEKKAQLIERVENECNLLLQKTDDLERTDQKVLPRYRQIVTLLPEHLLGDAFMMREFMHTYTGL 365
             .|:|.:..||::.    ..:..||:|..|.|.||....:.|.||....|||.|:.||:|.:..|
 Frog   390 LREEKKKYAERLKQ----WSRPRDDMECDDLKELPEPTPVKTRLPPESFGDAIMVLEFLHAFGDL 450

  Fly   366 LSGIEVFRQNLSFYEMTRALTAREIAGPLSDILLVLLGTVFDLQKEEEEEC------------AV 418
            ....:.|...::|..:..||...:..|||.::|...:..:|....|||||.            ..
 Frog   451 FDLKDEFPDGMTFEMLEEALVGSDPEGPLCELLFFFMSAIFQAVAEEEEEVEKEQVKETEPKDLA 515

  Fly   419 TYLDRAAQ-TQEPYWSMAQAAKSHLYAKRHFSFKVNELPLDALTLSEVLRLHLLGSGA---FVNE 479
            ..||..|. |:....::|..|.:  :.:.|...::..|.||:.||||:||||:|.|||   |.|.
 Frog   516 EALDEDADPTKSALTAVATLAAA--WPQLHQGCRLKNLDLDSCTLSEILRLHILASGADATFANA 578

  Fly   480 KAERWRVMYRNGYSSKEDPGLELRLEHSHILRILKNHSVYQLKFKDIMLLIRCLMSQIMTYSGTI 544
            |   :|...:.|:.:.:|..:||||.|..||:.|...|||.|:..:.:.::..|..:::|...|.
 Frog   579 K---YRYQKQGGFDATDDACVELRLSHPAILKKLSTVSVYALQPGEKLKILHALCGKLLTLVSTR 640

  Fly   545 NLIEERMEQTAKARQDLRALVVGENKR---LAAVEINRKKLTQMHHLEVNGVEPEKR-------- 598
            :.||:.:|:..:|:|:.|.|...:|:|   .||..|.::|..::...|:...:.:.|
 Frog   641 DYIEDYVEELRQAKQEFRELKAEQNRREREEAAARIRKRKEDKLKEQEMKMKDKQDRIKDEENKG 705

  Fly   599 ---------------------------------------------------------------EA 600
                                                                           :.
 Frog   706 FSKDTGNEEQDELDTSSENKDAEQRDQDSASDDEDDARPTGRKGKGIKGQRGFKDGKNRNGNFDG 770

  Fly   601 LVEKLKKSIAELHAQSDQQHRKHELQMLKLHSQ------LFNFLVYLGMDRCYRKYYVLESMPGI 659
            .:||.:...||...|..|::.|.|.::::...|      :|.    ||.||.||:::...|:||:
 Frog   771 GLEKKEVLTAEEEEQLRQEYLKREQELVEKIQQATACTNIFP----LGRDRWYRRFWTFFSVPGL 831

  Fly   660 FVEHSPDSLDTCLEQPITNKSQIEIRQQSALPKNRKDLRVYLLKLYGDDEKKTKKKAKHSLENKE 724
            |:|....:|...|.||     |...:|.:.    .|||.|    :.|           |......
 Frog   832 FLEEDYSNLTEDLLQP-----QPFSKQDTP----HKDLTV----VNG-----------HESSTSS 872

  Fly   725 NQEHRLNGSAEPMDVESDSPEAPTHFELLMCSGDKRSCIVHDSRNGQRQRWAYIYKAEEIDELIK 789
            .||.:         .|:|:|: |.:                     :..||.|....|::|:||:
 Frog   873 PQEDK---------KETDTPK-PVN---------------------RPNRWCYYSSIEQLDKLIE 906

  Fly   790 ALNPNGLREYELLQELSVLRSLIEQHAKTCPVDLLSLENETM--------RKKFMAAMESETNRK 846
            |||..|.||..|...|:..:|.|.|...:..|:...:.:.|:        |.|.:.|.||
 Frog   907 ALNTRGHRESALKDTLTQEKSKICQRLDSFSVNRFHIADNTLPTLDFKPARGKSLNASES----- 966

  Fly   847 YGEANFGLPNGTDLNEVMRLHLVDRIIQFENDIYTGDLGRLKVKDMEKWRSDLLGGNYDAQCKLQ 911
                     :.....:.:.|.|.|.|:..|:.||.|.||.:||.|.:.||:.|....|:.
 Frog   967 ---------SPVSAEKQLELRLCDLILDIEDRIYQGTLGAIKVPDRQLWRAALEKNTYEL----- 1017

  Fly   912 WGPGGKLEDEA---GSDNESHETHEEDDGALLGKYARKPYRDPGMYLAASADTKPLPDSDDEEDQ 973
                  |.|||   ||....:...||.:..:  |.:.|.     ..|....||.....:.....|
 Frog  1018 ------LNDEAKENGSSKPMNHGIEEMENDI--KQSAKE-----RLLGLKNDTPSATSTSTNTPQ 1069

  Fly   974 HTNAVSIPIAVHNMASALLQVEQAIGKRFLKEPYG------------------MKKWDPKQEALK 1020
            ..|.     ||..:|.||||:||.:.:::||.|.|                  .||.|..|.:.|
 Frog  1070 PMNN-----AVRYLARALLQIEQGVERKYLKAPLGDAEDTKKDTKSDKKKKDDKKKKDEDQNSEK 1129

  Fly  1021 --LACDSR-----LHQWEVSLMESTSFAQVFLHLNILHDCIQWRRSTNKSLCKVCRRGSDPEKML 1078
              ::...|     |.:|..||:.|.||:|:||||:.|...|.|.||...:.|||||:..|.|.|:
 Frog  1130 DDVSESGRVQRTVLDRWRESLLSSGSFSQIFLHLSTLDRSILWSRSILNARCKVCRKKGDGESMV 1194

  Fly  1079 LCDECNAGTHMFCLKPKLRSVPPGNWYCNDCVKSLGLSNGQNEKDKKQATKKKRKFIV---EEED 1140
            |||.|:.|.|::|::|||:.||.|:|:|.:|          :.|.:.:....::::.:   |||:
 Frog  1195 LCDGCDRGHHIYCVRPKLKYVPEGDWFCPEC----------HPKQRSRRLPSRQRYSMDSDEEEE 1249

  Fly  1141 DEATDEEEEEKKDDDMTDEDAEHENEKHDEDVEDDESVTSTPSSSRV-------NGRILRRPRTR 1198
            :|..|:||||:::::...|::|.|||: :|.:.::||........||       .|:...:|..:
 Frog  1250 EELEDQEEEEEEEEEEEQEESESENEE-EEVMSEEESPPKRGRPPRVQLPLKMRGGKAAGKPGPK 1313

  Fly  1199 PTSRRLTSKEIEEHAQEDVDSG-------DVSDDASLTAGEDTIEDESDEEKVCQKCFYDG---- 1252
            |.:.:.::.:....||:....|       .:...:.|:|.:......|....:.:....:|
 Frog  1314 PRTGKQSTPKNTPPAQKGSGRGRKTRSAPSLEPTSRLSAFDSPAYAVSPNASLVELVTVNGRGRG 1378

  Fly  1253 -----------GEIKCVQCRLFFHLECVHLKRPPRTDFVCKTCKPMPQRPRRRHSNMNGDHDRDE 1306
                       |.::               |....|    .:..|...||....||
 Frog  1379 RGRGRGRGRGRGRLQ---------------KSADNT----PSSSPFAFRPFSLDSN--------- 1415

  Fly  1307 EEPKAKRPRNSLRLSIDKTARPSNGNNNNNNNNSSVNNNNHRRSGRRTNEHMPLNSAALYDLLEQ 1371
            |..:..|...|..|...:|.....|....:.:.|||...:.|.|||....|   ..:|...|:.:
 Frog  1416 EPARPGRRARSQSLLPSQTEPKGRGKKRLSEDISSVGQGSRRSSGRHHGVH---ELSACEQLVVE 1477

  Fly  1372 IMKHKAAWPFLRPVLTSEVPDYHQIIKTPMDLAKIKSKLNMGAYQLNEELLSDIQLVFRNCDLYN 1436
            :::|..:|||:|.|...:||||..||:.|:.|..|:.|:|...|:...|.:.|:||:|.||..||
 Frog  1478 LVRHDDSWPFMRLVSKIQVPDYFDIIQKPIALNLIREKVNKCEYKCASEFIDDVQLMFSNCFEYN 1542

  Fly  1437 VEGNEIYDAGCQLERFVIDRCRDMQL 1462
            ...:....||.:|:.|.:...|.:.|
 Frog  1543 HHNSSEAKAGVRLQSFFVSEARKLGL 1568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acf	NP_536734.2	WAC_Acf1_DNA_bd	26..125	CDD:463140	35/98 (36%)
		DDT	346..411	CDD:214726	17/64 (27%)
		WSD	641..>666	CDD:464775	11/24 (46%)
		WSD	<774..805	CDD:464775	14/30 (47%)
		PHD_RSF1	1064..1109	CDD:277018	23/44 (52%)
		PHD	1244..1284	CDD:214584	4/54 (7%)
		Bromo_Acf1_like	1349..1463	CDD:99936	39/114 (34%)
baz1a	XP_004917293.2	WAC_Acf1_DNA_bd	37..136	CDD:463140	35/98 (36%)
		DDT	431..491	CDD:214726	16/59 (27%)
		WHIM1	599..644	CDD:464774	13/44 (30%)
		PTZ00121	<648..803	CDD:173412	21/154 (14%)
		WSD	808..926	CDD:464775	45/176 (26%)
		PHD_BAZ1A	1180..1225	CDD:277097	23/44 (52%)
		Bromo_Acf1_like	1455..1569	CDD:99936	40/117 (34%)