Protein Alignment Mccc1 and PCCA

DIOPT Version :9

• Sequence 1: NP_001247391.1
• Gene: Mccc1 / 43750
• FlyBaseID: FBgn0039877
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_016876094.1
• Gene: PCCA / 5095
• HGNCID: 8653
• Length: 744
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 240/604 - (39%)
• Similarity: 361/604 - (59%)
• Gaps: 47/604 - (7%)

  Fly     2 YAR----LLRNFGANARCFATEASPKVRPISKILISNRGEIACRVIRTARKLGVRTVAVFSDPDE 62
            |:|    :.||.|      :....|..:...|||::||||||||||||.:|:|::|||:.||.|.
Human    40 YSRQCLMVSRNLG------SVGYDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDA 98

  Fly    63 KSMHTQLADESYRVGEAASSASYLRGERILDIAKRSGAQAIHPGYGFLSESVEFAELCQREGIIF 127
            .|:|.::|||:..||.|.:|.|||..:.|::..|::.|||:|||||||||:.|||.....|.::|
Human    99 SSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVF 163

  Fly   128 MGPPSSAIRDMGIKSTSKAIMAAAGVPIINGYHGDDQSDECLQREADKIGFPLMIKAVRGGGGKG 192
            :||.:.||:.||.|..||.:...|.|..|.|:.|..:..|...|.|.:||:|:||||..||||||
Human   164 IGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKG 228

  Fly   193 MRIAEKPDDFLTALNSARTESEKSFGDSSVLLERYVRSPRHVEVQVFADQYGDAVYLWERDCSVQ 257
            ||||...::.......:..|:..||||..:|:|:::.:|||:|:||..|::|:|::|.||:||:|
Human   229 MRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQ 293

  Fly   258 RRHQKIIEEAPAPGLSEDLRRELGEAAVRAAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQVE 322
            ||:||::||||:..|..:.||.:||.||..|:||.|..||||||::|.:. :|:|:|||||||||
Human   294 RRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKK-NFYFLEMNTRLQVE 357

  Fly   323 HPITEMITGTDLVEWQIRIAAGEPLPLKQSEITRRGHAFEARIYAENPRGGF-LPGAGPLRYLST 386
            ||:||.|||.|||:..||:|.|.||..||::|...|.|.|.|:|||:|...| ||..|.|.....
Human   358 HPVTECITGLDLVQEMIRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQE 422

  Fly   387 PQPSNNVRVETGVREGDEVSVHYDPMIAKLVVWGENRTQALNSLVARLGEYHISGLDTNINFLID 451
            |.....|||::|::.|.::|::|||||:||:.:|.:||:||..:...|..|.|.|:..||..|.:
Human   423 PLHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRGVTHNIALLRE 487

  Fly   452 LASHPEFQLANVHTGFIDEQFDTLFPPIIISPQQVSQAALALVLNELQAAFR-NGNKDQDPFVAT 515
            :..:..|...::.|.|:.:.:...|...:::..:.:|  |..:.:.|..||: .....|:
Human   488 VIINSRFVKGDISTKFLSDVYPDGFKGHMLTKSEKNQ--LLAIASSLFVAFQLRAQHFQE----- 545

  Fly   516 PNARL--------NYSLVRRYDLKANEKVYSVAVKFDGEDMQIQVDNGDWQDAKVERVQDGSRLK 572
             |:|:        |:.|    .:|.::||::|....:|....::|              |||:|.
Human   546 -NSRMPVIKPDIANWEL----SVKLHDKVHTVVASNNGSVFSVEV--------------DGSKLN 591

  Fly   573 IRANINSNVTTYNASIDGT 591
            :.:..|......:.|:|||
Human   592 VTSTWNLASPLLSVSVDGT 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mccc1	NP_001247391.1	PccA	27..693	CDD:227111	234/575 (41%)
		CPSase_L_chain	27..135	CDD:278706	56/107 (52%)
		CPSase_L_D2	141..348	CDD:280881	102/206 (50%)
		Biotin_carb_C	362..469	CDD:214878	40/107 (37%)
		biotinyl_domain	626..691	CDD:133459
PCCA	XP_016876094.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4770
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D130620at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100368
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2097
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750