Protein Alignment Mccc1 and pyr1

DIOPT Version :10

• Sequence 1: NP_651896.1
• Gene: Mccc1 / 43750
• FlyBaseID: FBgn0039877
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_595900.1
• Gene: pyr1 / 2539661
• PomBaseID: SPBC17G9.11C
• Length: 1185
• Species: Schizosaccharomyces pombe
• Alignment Length: 685
• Identity: 231/685 - (33%)
• Similarity: 345/685 - (50%)
• Gaps: 84/685 - (12%)

  Fly     2 YARLLRNFGANARCFA---TEASPKVRPISKILISNRGEIACRVIRTARKLGVRTVAVFSDPDEK 63
            |..||.|...|...|:   ..:|......:|:|::||.|||.||.|||.:|.:.|||::|..|..
pombe     5 YDALLHNQSTNTNPFSKLQDRSSLLGEKFTKVLVANRSEIAIRVFRTAHELSMHTVAIYSYEDRL 69

  Fly    64 SMHTQLADESY---RVGEAASSASYLRGERILDIAKRSGAQAIHPGYGFLSESVEFAELCQREGI 125
            |||.|.|||||   :||:.:...:||..:.|:.||||:||..:|||||||||:.|||......|:
pombe    70 SMHRQKADESYPIGKVGQYSPVGAYLAIDEIVSIAKRTGANLVHPGYGFLSENAEFARKVNEAGM 134

  Fly   126 IFMGPPSSAIRDMGIKSTSKAIMAAAGVPIINGYHGDDQSDECLQREADKIGFPLMIKAVRGGGG 190
            .|:||....|..:|.|:.::||....|||::.|..|..:..|..:....:.|.|::|||..||||
pombe   135 QFVGPSPEVIDSLGDKTKARAIAIRCGVPVVPGTPGPVEHYEEAEAFVKEYGLPVIIKAAMGGGG 199

  Fly   191 KGMRIAEKPDDFLTALNSARTESEKSFGDSSVLLERYVRSPRHVEVQVFADQYGDAVYLWERDCS 255
            :|||:....|....:...||:|:..||||.:|.:||::..|:|:|:|:.||:.|:.::|.|||||
pombe   200 RGMRVVRSADTLKESFERARSEALASFGDGTVFIERFLDKPKHIEIQLMADKAGNVIHLHERDCS 264

  Fly   256 VQRRHQKIIEEAPAPGLSEDLRRELGEAAVRAAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQ 320
            |||||||::|.|||..|...:|:.|.:.|::.||.|.|..|||.||:||::. ..:|:|:|.|:|
pombe   265 VQRRHQKVVEIAPAKDLDPKIRQALYDDAIKIAKEVKYCNAGTAEFLLDQKG-RHYFIEINPRIQ 328

  Fly   321 VEHPITEMITGTDLVEWQIRIAAGEPLP---LKQSEITRRGHAFEARIYAENPRGGFLPGAGPLR 382
            |||.|||.|||.|:|..|:.:|||..||   |.|.:|:.||.|.:.|:..|:|..||.|..|.:.
pombe   329 VEHTITEEITGVDIVSAQLHVAAGFTLPEIGLTQDKISTRGFAIQCRVTTEDPNNGFAPDIGKIE 393

  Fly   383 -YLSTPQPSNNVRVETGVR--EGDEVSVHYDPMIAKLVVWGENRTQALNSLVARLGEYHISGLDT 444
             |.|.  ..|.||:: |..  .|..::.|||.|:.|..............::..|.|:.:.|:.|
pombe   394 VYRSA--GGNGVRLD-GANGFAGSVITPHYDSMLVKCTCHDATYEYTRRKMIRSLIEFRVRGVKT 455

  Fly   445 NINFLIDLASHPEFQLANVHTGFIDEQFDTLFPPIIISPQQVSQAALALVLNELQAAFRNGNKDQ 509
            ||.|::.|..|..|...|..|.|||:           :|             ||...:|:.|:.|
pombe   456 NIPFVLRLLMHDTFIQGNCWTTFIDD-----------TP-------------ELFQLYRSRNRAQ 496

  Fly   510 DPFVATPNARLNYSLVRRYD----LKANEKVYSVAVKFDGEDMQIQ-----------VDNG---- 555
            .......:..:|.|.::..:    || :|.|..|.:...|..:.:.           :|||
pombe   497 KLLAYLGDLAVNGSSIKGQNGEPALK-SEIVMPVLLDSTGNQIDVSHPSEKGWRKLLLDNGPAAF 560

  Fly   556 ---------------DWQDAKVERVQDGSRLKIRANINSNVTTYNASIDGTSVSLFSESGKVDFE 605
                           .|:||.    |.....::|.....|:..|.:....::.|| ...|...|:
pombe   561 AKAVRNHKRGLIMDTTWRDAH----QSLLATRVRTIDLVNIAPYTSHALASAYSL-EMWGGATFD 620

  Fly   606 VGQPKFLSAQGDQLGAVGSRIVAPMPGILEKVLVK 640
            |..........|:|    .|:...:|.|..::|::
pombe   621 VSMRFLHECPWDRL----RRLRKLVPNIPFQMLLR 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mccc1	NP_651896.1	PccA	26..478	CDD:443802	189/460 (41%)
		biotinyl_domain	626..691	CDD:133459	3/15 (20%)
pyr1	NP_595900.1	PycA	32..1182	CDD:440660	224/658 (34%)