Protein Alignment faf and UBP15

DIOPT Version :9

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: NP_014033.1
• Gene: UBP15 / 855350
• SGDID: S000004920
• Length: 1230
• Species: Saccharomyces cerevisiae
• Alignment Length: 1097
• Identity: 226/1097 - (20%)
• Similarity: 371/1097 - (33%)
• Gaps: 349/1097 - (31%)

  Fly  1653 WDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLT 1717
            |.......::...|:.|.:|.|||||:||:||..:.....|
Yeast   190 WHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFR------------------------ 230

  Fly  1718 GGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGL 1782
                         ..:..:|:.        |:...|...:.|   |..|..|..|.:
Yeast   231 -------------KLVYEIPTE--------HESPNNSVPLAL---QRAFYQLQVSDI-------- 263

  Fly  1783 WTHFKLLGEPVNLRE--------------QQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGSF 1833
                     |::..|              |.|..|....|::.|:..:|.......:|....|..
Yeast   264 ---------PLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEIFVGKM 319

  Fly  1834 SDQKICQECPHRYSKEEPFSVFSVDIRNHSSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKR 1898
            .....|....:..::.|.|....::::|..:|.||.:.|::.||:.|.:.|.......:... |.
Yeast   320 KSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQ-KG 383

  Fly  1899 VCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAK--LEGEVVEVGDNC 1961
            |..:..||||.:||||||||:.....:|.||.:|||..:|:.|:....:.|  |:.|      |.
Yeast   384 VIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSE------NK 442

  Fly  1962 QTNVETTKYELTGIVVHSGQASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAEC 2026
            ..|...  |.|.|::||||..|.|||::.|    ....:.|||:|||..|...   ..:::..|.
Yeast   443 DKNPYV--YNLHGVLVHSGDISTGHYYTLI----KPGVEDQWYRFDDERVWRV---TKKQVFQEN 498

  Fly  2027 FGGEYMGETYDNNLKRMQYRRQ--KRWWNAYMLFYTRCDQTPVQYEPSVEQLSLAESRNMVLPLP 2089
            ||.:.:.:.....:.|.:|:..  :|..:||||.|.|.:|......|.:|.           .:|
Yeast   499 FGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLES-----------DVP 552

  Fly  2090 KPI---------ERSVRHQNIR--------FLHS-RSIFSVEFFNFIKKLVSCNLLSARSNKITP 2136
            |.:         ||..:.:.||        .||| :.....|.|::.           ..:....
Yeast   553 KHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKEFIHYEGFDYF-----------AHDGFRL 606

  Fly  2137 AAEELSLLGVQLASQFLFHTGFRTKKS-LRGPVMEWYDALSHHIRSSALVRKWFANHALLSPPSR 2200
            .||||:..|:|..:..:..|   ||.| :...:.|     :.:|.....|:.|..::.
Yeast   607 FAEELNDSGLQQINLKVLRT---TKLSDIFASIKE-----TMNIPQERDVKYWKMDYR------- 656

  Fly  2201 LGEYILMAPSPDVRTVFVKLVVFFCHFAINDEPLTGYDGANLCEQVLISVLRLLKSE-----AAD 2260
                         |...::|.          :|:.       .|.|.|::...||.|     ...
Yeast   657 -------------RNSTLRLT----------QPIN-------FESVNITLQEALKKEKKRTMQTQ 691

  Fly  2261 YG-----------KHLPHYFSLFSMYVGLGTREKQQLLRLNVPLQFIQVALDDGPGPAIKYQYPE 2314
            ||           |.|....|...:::.....|.|.|.:|.......:..|||.....|:...||
Yeast   692 YGEEGVASTEEDDKALLETVSFLDLFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPE 756

  Fly  2315 FSK-------------------------------LHQVVSHLIRCSDVS---EKCQSSNQNARPL 2345
            .:|                               .|..|:.|.:.||:|   |...|||:..
Yeast   757 LTKGGIEPVFATDNKSNLLFVKSYDPHTQKLLGFGHFAVNQLQQLSDISAIIEDSISSNEKL--- 818

  Fly  2346 SNPFKDPNVAHEELTPLSTECMDLLFNRTGYIKKVIEDTNVGDEGLKLLQYCSWENPHFSRAVLT 2410
                    ..:||:.|.:...:        |:|:.|.|.:: |.|    ...|:|.|   .|||.
Yeast   819 --------TFYEEVQPGTINEI--------YMKETIYDADI-DTG----DIVSFEVP---GAVLP 859

  Fly  2411 ELLWQCGFAYCHD----MRHHTDLLLNILLIDDSWQHHRIHNALNGVAEEREGLLETIQRAKTHY 2471
            :..  ..:|...|    :|:...|..:  ..|.|.:.:       ||:.|.....|....|...|
Yeast   860 DTF--PVYATIKDFYSYLRYRVKLKFS--KFDGSSEEY-------GVSNEIPESFEFWISAYAPY 913

  Fly  2472 QKRAYQIIKCLTQLFHKSPIALQMLHTNSN---ITRHWSIAVEWL-------------------- 2513
            .    .:.:.:::..|..|..|:::...||   :.:..|:..::|
Yeast   914 D----DLARMVSKYAHVKPEYLKIIALYSNGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSVP 974

  Fly  2514 QGELDRQRGIGCQY--NSYSWSPPAQ---SNDNTNGYMLERSQ---------------------- 2551
            ..||:|.|.|...:  |||......:   :||.|....||:.|
Yeast   975 LKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIGFTDEEKENILLWTNTNFQ 1039

  Fly  2552 -----SAKNTW------SMAF-ELCPDEVSEKTDENNEPNLETNM------DENKSE 2590
                 |.:||:      |:.| .:.|:|.....:.|...|::|:.      |||.::
Yeast  1040 FQGLLSDQNTFKDVSKHSLLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATD 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	101/415 (24%)
		UCH	1668..2059	CDD:278850	98/408 (24%)
UBP15	NP_014033.1	COG5077	1..1229	CDD:227409	226/1097 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810