Protein Alignment faf and UBP2

DIOPT Version :9

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: NP_014767.3
• Gene: UBP2 / 854291
• SGDID: S000005650
• Length: 1272
• Species: Saccharomyces cerevisiae
• Alignment Length: 1658
• Identity: 298/1658 - (17%)
• Similarity: 525/1658 - (31%)
• Gaps: 663/1658 - (39%)

  Fly   577 DKNGVMAQKVLKLFWTLAHSQEVPPEVLDQALGAHVKILDYSCSQERDAQKTIWLDKCVDE---- 637
            |:||.:.:. |.|:.|..:.|..|.:|.|   |.|:...|.:.:......     |:.:|:
Yeast    28 DRNGSVIED-LPLYGTSINQQSTPGDVDD---GKHLLYPDIATNLPLKTS-----DRLLDDILCD 83

  Fly   638 ---LKSGDGWV----LPALRLIRDICCLYDTTTNHAQRTQTSTNRQQVIERLQNDYSLVILVTNS 695
               |.|.|..|    |.:..::::....|.|..:..:.....:...||:.:.:::|..:     |
Yeast    84 TIFLNSTDPKVMQKGLQSRGILKESMLSYSTFRSSIRPNCLGSLTDQVVFQTKSEYDSI-----S 143

  Fly   696 LTAYME-KVRQMVTDSPGL---------DATRILIDGRFPHH----VQIAERLEFLKFLLKDGQL 746
            ...|.: .|.|.|..:|.|         |..:|.|     :|    |::.:.||.||
Yeast   144 CPKYNKIHVFQAVIFNPSLAEQQISTFDDIVKIPI-----YHLKVSVKVRQELERLK-------- 195

  Fly   747 WLCADQAKQI----WHCLAVNAVFPADREECFRWFGKLMGEEPDLDPGINKDFFENNILQLDPHL 807
                   |.:    :|.|  :.:...||                    ::...|:::    ||:|
Yeast   196 -------KHVGVTQFHSL--DHLHEYDR--------------------VDLSTFDSS----DPNL 227

  Fly   808 LTESGIKCFERFFKAVNSKEDKLKAIHRGYMLDNEDLIGKDYLWRVITTGGEEIASKAIDLLKEV 872
            | :.||                       |:.|:.:        ::|          .|::.|.
Yeast   228 L-DYGI-----------------------YVSDDTN--------KLI----------LIEIFKP- 249

  Fly   873 STALGPRLQENIAEFHEMFIGECCSRLRTHYGNIVILGKTQLQEELDAPDQSDNTNDESKDSKMR 937
                    :.|..|.||.|..:.   ::..|..:.:  |.:..::.:.|.|.|
Yeast   250 --------EFNSPEEHESFTADA---IKKRYNAMCV--KNESLDKSETPSQVD------------ 289

  Fly   938 FIEAEKMC--RILKVLQEYVKECDRSFSGDRVHLPLSRVTRGKNTILYIRFQNPGRSID--DMEI 998
                   |  .:.|:           |.|     ||:|.::.:          |.::||  ::.:
Yeast   290 -------CFYTLFKI-----------FKG-----PLTRKSKAE----------PTKTIDSGNLAL 321

  Fly   999 VTHSNETMAAFKRNLLKRIKGTSTANIKVD-----LF--YANDEMIGVSDEINPLYQYTIRDK-- 1054
            .||.|......|...        .|:.::|     :|  |...:|:   |.:|.|....||:.
Yeast   322 NTHLNPEWLTSKYGF--------QASSEIDEETNEIFTEYVPPDMV---DYVNDLETRKIRESFV 375

  Fly  1055 ---MNL-------TAKLTPVGTGLASSPDSSSDSSTGSPPRPCPDMQRVE-SESTLP-------- 1100
               :.|       |:.|.|      :||..::.|..|        |..:: |.||||
Yeast   376 RKCLQLIFWGQLSTSLLAP------NSPLKNTKSVKG--------MSSLQTSFSTLPWFHLLGES 426

  Fly  1101 --GVIISQNYQYTEFFLKLYQLGSDLEHGRLRDSAKVLLHL----LPCDRQTIRQLKIMCKVPKA 1159
              .::::.|.|               .|..| |:....::|    ...||..||..:.:..:...
Yeast   427 RARILLNSNEQ---------------THSPL-DAEPHFINLSVSHYYTDRDIIRNYESLSSLDPE 475

  Fly  1160 AVTV---AVTGDKIAKDEEEKLYPTEQAGIEDEEEHCTPEQMFLHPTPAQVLYNLSVLHGLLIPA 1221
            .:.:   |:|            |...:.|......:|..:         .::...::.:.||:..
Yeast   476 NIGLYFDALT------------YIANRKGAYQLIAYCGKQ---------DIIGQEALENALLMFK 519

  Fly  1222 LDP-------LGESALLVQSAWMHSGCAHFVLELLTK-NNFLPSADMHTKRASFQCVLRLAKLFL 1278
            ::|       |.|:.||....:..|..:......||. .|.|.....:||.         .||..
Yeast   520 INPKECNISELNEATLLSIYKYETSNKSQVTSNHLTNLKNALRLLAKYTKS---------DKLKF 575

  Fly  1279 YIVGS---VLSRVGDEPMICD-LDNGSRSQVDILKQNFSTMPSSSQG-TLRAISAKLAVILAREM 1338
            |:...   .||:..|...|.: :|.      ||:|..:|...:.|.| .|....|...:.:::..
Yeast   576 YVDHEPYRALSQAYDTLSIDESVDE------DIIKTAYSVKINDSPGLKLDCDRALYTIAISKRS 634

  Fly  1339 LSASPEGDRCRTLFSSTLQWSCPDISTIKAVVQLAWASSCGNLQALGNSSGD----------FED 1393
            |.          || :.|...||..|......:|.:..:...||...|:|.:          |::
Yeast   635 LD----------LF-NFLTEECPQFSNYYGPEKLDYQEALKLLQVNENASDETILKIFKQKWFDE 688

  Fly  1394 EVIVPDGQDFSMCKEALEVLTI--------SFILNPSANEALTSDPNWPKFITSIVLKNPLRHVR 1450
            .|..||  .|.:.:.||..::|        :|:|..:.:.......|||..|.:|
Yeast   689 NVYEPD--QFLILRAALTKISIERNSTLITNFLLTGTIDPNSLPPENWPTGINNI---------- 741

  Fly  1451 QVASEQLFLASTYCAGDRRPFVYMVNLL-----VGALKTLVPQYESTCAEFFSVLCRTLSYGCIY 1510
                      ...|        |:.:||     :..|:..|.:|:.|...|...|..:   |.|.
Yeast   742 ----------GNTC--------YLNSLLQYYFSIAPLRRYVLEYQKTVENFNDHLSNS---GHIR 785

  Fly  1511 N-WPLQISEGLLGDEIKWLQRIRENVHATGDTQVHEELLEGHLCLAKELMFFLGADSKAQL---- 1570
            . ...:||.|.:...|:::.::|...:|    .||..  |..:..:|||.:...|.|..::
Yeast   786 RIGGREISRGEVERSIQFIYQLRNLFYA----MVHTR--ERCVTPSKELAYLAFAPSNVEVEFEV 844

  Fly  1571 --NELIHE---LIDDFLFTASREFLHLRRHGSLRQDTVPPPVCRSPHTIAAACDLLIALCQLCVP 1630
              |:::.:   |.|....|....|
Yeast   845 EGNKVVDQTGVLSDSKKETTDDAF----------------------------------------- 868

  Fly  1631 NMKLLTNTLIDFVCTD-------TDPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYM 1688
            ..|:...:|||....|       ||..|:                  ||
Yeast   869 TTKIKDTSLIDLEMEDGLNGDVGTDANRK------------------KN---------------- 899

  Fly  1689 VPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKN 1753
                     .::.|..::.||.:|            |.|....|.:    ||..:|:.|...|:
Yeast   900 ---------ESNDAEVSENEDTTG------------LTSPTRVAKI----SSDQLENALEMGRQ- 938

  Fly  1754 YHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNL---REQQDAVE--FFMSLLESLD 1813
                     |.:...:|:...|  :..|        .||:..   .||.|.|:  |:.:..:|:.
Yeast   939 ---------QDVTECIGNVLFQ--IESG--------SEPIRYDEDNEQYDLVKQLFYGTTKQSIV 984

  Fly  1814 EGLKALGQPQLMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNH-SSLTESLEQYVKGEL 1877
            .          ::||       .|:       .:|.|.|....::|.:| ..:.::.:.|.|.|.
Yeast   985 P----------LSAT-------NKV-------RTKVERFLSLLINIGDHPKDIYDAFDSYFKDEY 1025

  Fly  1878 L---EGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDM 1939
            |   |..|            .::.|.|...|.:|.:|::|..||.||:...|..:...|..::.|
Yeast  1026 LTMEEYGD------------VIRTVAVTTFPTILQVQIQRVYYDRERLMPFKSIEPLPFKEVIYM 1078

  Fly  1940 EPYT-----------------------------------VSGLAK----------LEGEVV---- 1955
            :.|.                                   .|||.:          ||.:.:
Yeast  1079 DRYADTENPLLLAKKKETEEMKQKLKVMKNRQRELLSRDDSGLTRKDAFLESIKLLESDTIKKTP 1143

  Fly  1956 -------EVGDNCQTNVETTK----------------------------YELTGIVVHSGQASGG 1985
                   :|....:.||:...                            |.|..:.:|.|:||.|
Yeast  1144 LKIEAANDVIKTLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYSLFSVFIHRGEASYG 1208

  Fly  1986 HYFSYILSKNPANGKCQWYKFDDGEVTECKMHE 2018
            ||:.||..:| .||  .|.|::|..::|.:..|
Yeast  1209 HYWIYIKDRN-RNG--IWRKYNDETISEVQEEE 1238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	81/446 (18%)
		UCH	1668..2059	CDD:278850	81/444 (18%)
UBP2	NP_014767.3	RPT	585..641	CDD:404348	16/72 (22%)
		RPT	658..719	CDD:404348	12/62 (19%)
		Peptidase_C19J	735..1256	CDD:239131	123/700 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810