Protein Alignment faf and USP47

DIOPT Version :9

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: NP_001317137.1
• Gene: USP47 / 55031
• HGNCID: 20076
• Length: 1375
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 134/557 - (24%)
• Similarity: 209/557 - (37%)
• Gaps: 181/557 - (32%)

  Fly  1666 GFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLGSALFSGPA 1730
            |:.||.|...|||:||:||.|:|.|..|..:.:      .:.|:...|
Human   186 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYK------WEFEESEED----------------- 227

  Fly  1731 SALVSLP------------SSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLW 1783
             .:.|:|            |....||  ..||.:::               |..:.:      .|
Human   228 -PVTSIPYQLQRLFVLLQTSKKRAIE--TTDVTRSF---------------GWDSSE------AW 268

  Fly  1784 THFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGSFSDQKICQECPHRYSK 1848
                         :|.|..|....:.::|::..|...|..|:|....|...|...|.||.:...:
Human   269 -------------QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWR 320

  Fly  1849 EEPFSVFSVDIRNH------SSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPV 1907
            .:.:....:.||.:      :|:.|:|..:::.|:|:|.:.|.|::|.||....|.:.....|.:
Human   321 IDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYL 385

  Fly  1908 LAIQLKRFEYDYERVCAIKFNDYFEFPRILDM--------------EPYTVSGLAKLEG------ 1952
            |.:|||||::||..:..||.||...||..|||              |..|.|| |:.||
Human   386 LTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSG-AENEGSCHSDQ 449

  Fly  1953 --------EVVEVGDNCQTNVETTK------------YELTGIVVHSGQASGGHYFSYILSKNPA 1997
                    :.|:.|...:||..|.|            |||..::||||.|:||||::.|.|.:..
Human   450 MSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSDE 514

  Fly  1998 NGKCQWYKFDDGEVTECKMHEDEEMKAECFGGE-----YMGETYDNNLKRMQYRRQKRWWNAYML 2057
                |||.|:|..|:..   ..|::| :..||.     |....:.::.            |||||
Human   515 ----QWYSFNDQHVSRI---TQEDIK-KTHGGSSGSRGYYSSAFASST------------NAYML 559

  Fly  2058 FY-----------TRCDQTP------VQYEPSVEQLSLAESRNMVLPLPKPIERSVRHQNIRFLH 2105
            .|           ...|:.|      ||.|..:|:   .|.|.      :.|||:.....:..||
Human   560 IYRLKDPARNAKFLEVDEYPEHIKNLVQKERELEE---QEKRQ------REIERNTCKIKLFCLH 615

  Fly  2106 SRSIFSVEFFNFIKKLVSCNLLSARSNKITPAAEELS 2142
            .           .|:::..|.|....:|....|.|::
Human   616 P-----------TKQVMMENKLEVHKDKTLKEAVEMA 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	115/471 (24%)
		UCH	1668..2059	CDD:278850	113/453 (25%)
USP47	NP_001317137.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..452		7/27 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	840..859
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	880..968
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	983..1024

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810