DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment faf and Usp5

DIOPT Version :9

Sequence 1:	NP_524612.2	Gene:	faf / 43749	FlyBaseID:	FBgn0005632	Length:	2778	Species:	Drosophila melanogaster
Sequence 2:	NP_001246589.1	Gene:	Usp5 / 38375	FlyBaseID:	FBgn0035402	Length:	827	Species:	Drosophila melanogaster

Alignment Length:	380	Identity:	79/380 - (20%)
Similarity:	140/380 - (36%)	Gaps:	128/380 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1632 MKLLTNTLIDFVCTDTDPLREW-------DYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMV 1689
            ||....::::........:.||       ..|.|| |.|  |:.|::|.|.:||:|||:|.|:::
  Fly   292 MKKSEKSMVELELDINQRIGEWTALTESESELQPV-AGP--GYTGMRNLGNSCYINSVMQVLFVI 353

  Fly  1690 PAVR---VGILRAHGAATTDGE---DFSGDSDLTGGGLGSALFSGPASALV--SLPSSSSTIEDG 1746
            |..:   ||.    ||.....|   |.:.|.::....||:.|.||..|::.  :|.:..||   |
  Fly   354 PDFQQRFVGT----GAERYFKEFPSDPANDFNIQMAKLGTGLQSGKYSSIAENTLDTDHST---G 411

  Fly  1747 LHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGE---PVNLREQQDAVEFFMSL 1808
            :.              .|:|.:                   ::|:   ..:.::||||.:|::.|
  Fly   412 IS--------------PAMFKN-------------------IVGKNHPDFSTKQQQDANDFYLHL 443

  Fly  1809 LESLD----------EGLKALGQPQLMNATLGGSFSDQKICQEC--PH--RYSKEEPFS------ 1853
            |..||          :.||.|.:.::                ||  .|  :|:..|.:|
  Fly   444 LTLLDRNSRNQTNPADALKFLLEDRV----------------ECLASHKVKYNTREEYSFRLPVP 492

  Fly  1854 ---VFSVD------------------------IRNHSSLTESLEQYVKGELLEGADAYHCDKCDK 1891
               ..::|                        :|:...|...||::...||:|   .::......
  Fly   493 LDKATNLDEVREFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELIE---QFYSTAIGS 554

  Fly  1892 KVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSG 1946
            |....|...:..:|..|.|.:.:|....:.| ..|.:...:.|..||:..:..:|
  Fly   555 KTNARKITRLATMPDCLMIHVGKFTLGDDWV-PKKLDVSVDMPDELDLSNWRSAG 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	70/339 (21%)
faf	NP_524612.2	UCH	1668..2059	CDD:278850	69/337 (20%)
Usp5	NP_001246589.1	UBP14	24..825	CDD:227532	79/380 (21%)
		zf-UBP	204..278	CDD:280334
		Peptidase_C19B	333..823	CDD:239123	69/336 (21%)
		UBA1_UBP5_like	631..674	CDD:270480
		UBA2_UBP5	696..737	CDD:270569
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940