Protein Alignment faf and DUBAI

DIOPT Version :10

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: NP_610784.1
• Gene: DUBAI / 36361
• FlyBaseID: FBgn0033738
• Length: 852
• Species: Drosophila melanogaster
• Alignment Length: 949
• Identity: 198/949 - (20%)
• Similarity: 299/949 - (31%)
• Gaps: 374/949 - (39%)

  Fly  1316 PSSSQGTLRAISAKLAVILAREMLSASPEGDRCRTLFSSTLQWSCPDISTIKAVVQLAWASSCGN 1380
            |.|:.|...|...    :|.:.|.:.||.|:...:..|..        ..|||:  ||:..|. :
  Fly    31 PMSANGMANAEEN----VLPKGMDTGSPAGESLNSNRSGK--------RDIKAL--LAYLQSI-D 80

  Fly  1381 LQALGNSSGDFEDEVIV-------PDGQDFSMCKEALEVLTISFILNPSANEALTSDPNWPKFIT 1438
            :...|::.....:.|||       |.|......||  :|..:...| .:.||         ||..
  Fly    81 MPEQGHNVMAICERVIVDLARLQIPRGASCPRLKE--DVCQVGAFL-ATRNE---------KFHQ 133

  Fly  1439 SIVLKNPLRHVRQVASEQLFLASTYCAGDRRPFVYMV---NLLVGALKTLVPQ--YESTCAEFFS 1498
            ...    ||.|.::.::..|.....||   ...|:.:   ..::.|:.:|:.|  .:|:..:..:
  Fly   134 MFY----LRVVYELITKSPFEPPPSCA---VAIVFQLFDSTQILEAVHSLLEQNVQDSSIKKTVN 191

  Fly  1499 VLCRTLSYGCIY-----NWPLQISEGL-------LGDEI-------------------------- 1525
            :||..::| |.:     .|.|.:.:||       |.|||
  Fly   192 LLCDWITY-CTFCSTLNLWVLALLKGLRDQGKMALLDEIAMDNIEKLFHVMIFPALRQKAAPVVF 255

  Fly  1526 --------------KWLQRI-RENVHATGDTQVHEEL-LEGHLCLAKELMFFLGADSKAQLNELI 1574
                          |.|.|| |...:....:...:|: ||...||             .||.:|.
  Fly   256 HMLSTINQTPEVFHKILPRIPRVLQYVKNQSTTMDEIGLETKKCL-------------QQLVDLT 307

  Fly  1575 HELI-----DDFLFTASREFLHLRRHGSLRQDTVPPPVCRSPHTIAAACDLLIALCQLCVPNMKL 1634
            ..|:     .|.|:.|:::.|         |...|.|.|             :||.:....|.:
  Fly   308 SALMLRFYDQDELYVATKKAL---------QTYEPSPNC-------------VALAKAMHENAQ- 349

  Fly  1635 LTNTLIDFVCTDTDPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRA 1699
                                   |.|.|..:  .||.|.|.|||||||||.|.|.
  Fly   350 -----------------------PWGRRNAR--VGLVNLGNTCYMNSVLQALAMT---------- 379

  Fly  1700 HGAATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQA 1764
                    .|||..                    :.|...:|               |:|..||.
  Fly   380 --------SDFSRQ--------------------ILLIECNS---------------VLLMKVQQ 401

  Fly  1765 IFAHLGHSALQYYVPRGLWTHFKLLG--EPVNLRE--QQDAVEFFMSLLESLDE----------- 1814
            ..| |.|.:|:|.:     |..::|.  .|.:...  |||:.||...||:.|.|
  Fly   402 QIA-LMHHSLRYEL-----TPSRVLNATRPPSFTPGLQQDSSEFLGYLLDLLHEHEINSSSVTGH 460

  Fly  1815 ---------------------------------------------------------------GL 1816
                                                                           ||
  Fly   461 SVGPPKTGREVDDVPALLSEDILSSGVIPYNSKDHELSSGSNSDNCNHKPTPTPPATPTKATNGL 525

  Fly  1817 KALGQ-------PQLMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDI--------RNHSSLT 1866
            |..||       |..::.|..|..|....|..|......|:.|....:..        ..:.|:.
  Fly   526 KQQGQQVDQAKPPSTIDKTFAGKLSTTYRCLNCGWESRNEDSFRELQLSFPDDKEDCGATNYSVQ 590

  Fly  1867 ESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYF 1931
            :.:|.|...|.|:|.:.|.|.:|.|.....:.:.|.:.|..|.:.||:|:||.:.....|.
  Fly   591 DLIEYYCSPEKLDGDNQYFCPQCKKLCDAERHIGVTQAPKNLILTLKQFKYDQKYHFRTKL---- 651

  Fly  1932 EFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELTGIVVHSGQA-SGGHYFSYIL--S 1993
             ..::...|..||...||         |:.| .:.|..|:|...|||:|.: ..||||::..  :
  Fly   652 -MHKVFHDESVTVKMSAK---------DSLQ-EMSTVHYDLYAGVVHAGYSMDSGHYFTFAADQA 705

  Fly  1994 KNPANGKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYDNNLKRMQYRRQKRWWNAYMLF 2058
            ||       ||||:|..||..|   .|||               :||....        ..|:||
  Fly   706 KN-------WYKFNDNVVTHSK---PEEM---------------HNLTSPN--------TPYILF 737

  Fly  2059 YTRC----DQTPVQYEPSVEQLSLAESRNMVLPLPKPIE 2093
            |..|    :...|....|...:|.:..:.:.:||..|::
  Fly   738 YKMCGHSNESNSVTASCSSSMVSGSNDQVVSVPLSPPLK 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	Ubl1_cv_Nsp3_N-like	<994..1060	CDD:475130
		peptidase_C19C	1666..2064	CDD:239124	111/497 (22%)
		DUF3517	2198..2566	CDD:463438
DUBAI	NP_610784.1	Peptidase_C19H	359..739	CDD:239129	109/486 (22%)