DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment faf and Usp14

DIOPT Version :9

Sequence 1:	NP_524612.2	Gene:	faf / 43749	FlyBaseID:	FBgn0005632	Length:	2778	Species:	Drosophila melanogaster
Sequence 2:	NP_001260321.1	Gene:	Usp14 / 34387	FlyBaseID:	FBgn0032216	Length:	475	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	111/478 - (23%)
Similarity:	166/478 - (34%)	Gaps:	161/478 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1656 LPPVGARPTKGF---------------CGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATT 1705
            :|.|.|.|.|..               .||.|.|.|||||:.:|.|..||.:|..:
  Fly    77 VPEVPATPVKFIEDMNEAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVPELRTAL--------- 132

  Fly  1706 DGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLG 1770
              ..||.|    |....|..|           |.||.::.....:.|...|..:..:||:
  Fly   133 --STFSND----GTDTMSTAF-----------SISSAMKSIFAQMEKGTTVTPIVLLQAL----- 175

  Fly  1771 HSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQ----------PQLM 1825
            |.|.         ..|...||....| ||||.|.:..:|:.|.:.|:...|          ...:
  Fly   176 HRAS---------PQFAQTGENGTYR-QQDANECWAEILKMLQQKLRPKNQEPSNTVQKRHSSFI 230

  Fly  1826 NATLGGSFSDQKICQECPHRYSKEEPFSV-----------FSVDIRNHSSLTES--LEQYVKGEL 1877
            :...||:|..:...:|.|     :||.:|           .|:|::...|..:|  .||.||...
  Fly   231 DQFFGGTFEVKMSSEEDP-----DEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSE 290

  Fly  1878 LEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPY 1942
            ..|.||.:          ::...|.:||..|.:|..||:|..:.....|.....:||  :|.:.:
  Fly   291 TLGRDAKY----------IRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFP--IDFDAF 343

  Fly  1943 TV-------------SGLAKLEGEVVEVGDNCQTN-----VETTKYE-----------------L 1972
            .:             |....||.:.:|| |..:.|     .:..|||                 |
  Fly   344 ELCTPELQNKLCPMRSKFKDLEDKKMEV-DVVKRNEPNEEKKDVKYEQFWFDDDLGSNNSGYYTL 407

  Fly  1973 TGIVVHSGQ-ASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETY 2036
            ..::.|.|: :|.|||.:::.|....     |:||||.||:.....|...:..   ||:
  Fly   408 QAVLTHKGRSSSSGHYVAWVRSSGDV-----WFKFDDDEVSAVATDEILRLSG---GGD------ 458

  Fly  2037 DNNLKRMQYRRQKRWWNAYMLFY 2059
                          |..||:|.|
  Fly   459 --------------WHCAYVLLY 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	106/468 (23%)
faf	NP_524612.2	UCH	1668..2059	CDD:278850	105/449 (23%)
Usp14	NP_001260321.1	UBQ	4..73	CDD:214563
		UBQ	5..73	CDD:294102
		UCH	103..467	CDD:278850	105/450 (23%)
		Peptidase_C19A	105..467	CDD:239122	105/448 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456919
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840