Protein Alignment faf and Usp16-45

DIOPT Version :10

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Alignment Length: 1292
• Identity: 249/1292 - (19%)
• Similarity: 382/1292 - (29%)
• Gaps: 480/1292 - (37%)

  Fly   918 LDAPDQSDNTNDESKDSK--MRFIEAEKMCRILK---VLQEYVKECDR--SFSGDRVHLPLSR-- 973
            |.:|.|||.....:...:  .:.::|.::.|:||   :|.| ..:|.:  ..:|.......|.
  Fly    29 LGSPGQSDGATPTTASCQHIKKAVDAARLRRLLKSTGLLYE-CSQCQKLGKTAGSAAGAGASEGA 92

  Fly   974 VTRGKNTILY--------------------------IRFQNP----------GRSID------DM 996
            |..|.|.:.:                          ..:|.|          .||.|      ||
  Fly    93 VGPGGNPVTFEFDNTLWLCLKCGSQLCGRARHKHALEHYQTPHSDSHALAMNTRSFDIWCYECDM 157

  Fly   997 EIVTHSNETMAAFKRNLLKRIK---------GTSTANIKVDLFYANDEMIGVSDEINPLYQYTIR 1052
            :|.::       .::|||:.::         .|||..                 ...|...| |.
  Fly   158 KICSN-------LRKNLLECVELVKKLAQKPPTSTVT-----------------PSTPTISY-IE 197

  Fly  1053 DKMNLTAK-LTPV--GTGLASSPDSSSDSS---------TGS-----------PPRPCPDMQRVE 1094
            :|:....: |||:  .|| .|..||||..|         .||           ||.|...:...:
  Fly   198 EKLKAALEHLTPIVPMTG-GSFDDSSSRGSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSD 261

  Fly  1095 SESTLPGVIISQNYQYTEFFLKLYQLGSDLEHGRLRDSAKVLLHLLPCDRQTIRQLKIMCKVPKA 1159
            |.:::|| :..:..||                                                :
  Fly   262 SLTSVPG-MAKRIDQY------------------------------------------------S 277

  Fly  1160 AVTVAVTGDKIAKDEEEKLYPTEQAGIEDEEEHCTPEQMFLHPTPAQVLYNLSVLHGLLIPALDP 1224
            |.|...||:|       :|...|...||:|.   .|.                      :..|..
  Fly   278 ATTNGNTGNK-------RLLTLETPRIENER---LPR----------------------VRGLTN 310

  Fly  1225 LGESALLVQSAWMHSGCAHFVLELLTKNNFLPSADMHTKRASFQCVLRLAKLFLYIVGSVLSRVG 1289
            ||.:...                                .|..||:.:..  ||..|...||..|
  Fly   311 LGNTCFF--------------------------------NAVMQCLAQTP--FLLSVLKELSEPG 341

  Fly  1290 DEPMICDLDNGS---RSQVDI-LKQNFSTMPSSSQGTLRAISAKLAVILAREMLSASPEGDRCRT 1350
            :|.:   |..|:   :.:.|| |.....|:  ||.|.|.|     |:..|.|.|.|.......|.
  Fly   342 EEFI---LPGGTFTIKDKGDIELPMIKGTL--SSWGGLTA-----ALANALEELQAGGSVFTPRK 396

  Fly  1351 LFSSTLQWSCPDISTIKAVVQLAWASSCGNLQALGNSSGDFEDEVIVPDGQDFSMCKEALEVLTI 1415
            || ..|...||..                       :.||..|               |.|:|
  Fly   397 LF-DRLCVKCPQF-----------------------TGGDQHD---------------AHELL-- 420

  Fly  1416 SFILNPSANEALTSDPNWPKFITSIVLKN---PLRHVRQVASEQLFLASTY--CAGDR--RPFVY 1473
            ..:|....||.|       |....::|:|   ..:.|..|:.|.......|  .||||  ||...
  Fly   421 RQLLESVRNEDL-------KRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQV 478

  Fly  1474 MVNLLVGALKTLVPQYESTCAEFFSVLCRTLSYGCIYNWPLQISEGLLGDEIKWLQRIREN---- 1534
            ....||..|         ||.:..:|..|       :.:.|.:|..:..::.:..||.:.:
  Fly   479 FRGFLVSTL---------TCQDCHNVSSR-------HEYFLDMSLPVAVEKPQPPQRRKPSPELS 527

  Fly  1535 --------VHATGDTQVHEELLEGHL-CLAKELMFFLGADSKAQL-------------------- 1570
                    ..:||...::.:..:|.: ..|....|||.|...|.|
  Fly   528 LTSSSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEKERQRKAKRA 592

  Fly  1571 -------------------NELIHELIDDFLFTASREFLHLRRHGSLRQ------DTVPPPVCRS 1610
                               |||...:..|....||......:.:..|.|      |:....|..|
  Fly   593 AKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTS 657

  Fly  1611 PHTIAAACDLLIALCQLCVPNMKLLTNTLIDFVCTDTDPLREW-----DYLPPVGAR-------- 1662
            .|:.|...|.|:.  ....|:    ||.:.....:.|.|.:.:     :..||...|
  Fly   658 EHSDADVEDNLVE--DTAAPS----TNNVPSSTASLTAPSKTYMDSNGNAQPPGEKRDDTPEHMD 716

  Fly  1663 -----PTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLG 1722
                 ..:...|:..:.|....||                      :|.......::.:.|.||
  Fly   717 KDSLEEDENDSGIATSPAPTATNS----------------------STSTSATGNNNSVAGSGL- 758

  Fly  1723 SALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFK 1787
                ||.:.||....:.:|.:..||.:...:    :::.| ::.|..|.|
  Fly   759 ----SGSSGALEDPLAPASLVTAGLSEKGAS----VIRQV-SVGAEQGAS--------------- 799

  Fly  1788 LLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATL-GGSFSDQKICQECPHRYSKEEP 1851
                  |..|..|.....:...|......:|:.|.|.....: ..|:||..  .....||..|:
  Fly   800 ------NGTEDADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSYSDWS--TTIAPRYQCED- 855

  Fly  1852 FSVFSVDIRNHSSLTESLEQYVKGELLEGADAYHCDKC-------DKKVVTV-----KRVCVKKL 1904
                     ...|:...|..:...||:.|.:...||.|       |.|..:|     |::.|...
  Fly   856 ---------GECSVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKAKSVNTNATKQLLVSSP 911

  Fly  1905 PPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTK 1969
            |.||.:.||||:.. .|....|......:|.:||:..:..|.:..|        .|.....:...
  Fly   912 PAVLILHLKRFQLG-PRCIFRKLTRPVSYPNLLDIAAFCGSKVKNL--------PNIDRKQKKLL 967

  Fly  1970 YELTGIVVHSGQASGGHYFSYI-LSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAE 2025
            |.|.|:|.|||...||||.:|: :....|.|..:|.....|...|....:|:..|.|
  Fly   968 YALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLKKLE 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	Ubl1_cv_Nsp3_N-like	<994..1060	CDD:475130	14/80 (18%)
		peptidase_C19C	1666..2064	CDD:239124	80/374 (21%)
		DUF3517	2198..2566	CDD:463438
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	7/50 (14%)
		UBP12	<307..990	CDD:227847	174/870 (20%)
		Peptidase_C19	307..>512	CDD:470612	67/312 (21%)
		Peptidase_C19K	<849..1123	CDD:239132	51/195 (26%)