Protein Alignment faf and Usp47

DIOPT Version :9

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: XP_006230106.1
• Gene: Usp47 / 308896
• RGDID: 1310411
• Length: 1395
• Species: Rattus norvegicus
• Alignment Length: 1324
• Identity: 261/1324 - (19%)
• Similarity: 427/1324 - (32%)
• Gaps: 473/1324 - (35%)

  Fly  1529 QRIRENVHA-TGDTQVHEELLE--GHLCLAKELMFFLGADSKAQLNELIH----ELIDDFLFTAS 1586
            :||..|:.| |...::.|::..  |::....:|.:..|.:: |.|..|.|    .|:|.......
  Rat    58 ERITVNLPASTPVRKLFEDVANKVGYINGTFDLTWGNGINT-ADLAPLDHTSDKSLLDANFEPGK 121

  Fly  1587 REFLHLRRHGSLRQDTVPPPVC--RSPHTIAAACDLLIALCQLCVPNMKLLTNTLIDFVCTDTDP 1649
            :.||||     ..:|...|.:.  .|.|...:..|..|.    .:|....:.:| .|:|.
  Rat   122 KNFLHL-----TDKDGEQPQMLLDDSSHVDDSVHDRFIG----PLPREGSVAST-SDYVS----- 171

  Fly  1650 LREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDS 1714
             :.:.|...:....| |:.||.|...|||:||:||.|:|.|..|..:.:      .:.|:...|
  Rat   172 -QSYSYSSILNKSET-GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYK------WEFEESEED- 227

  Fly  1715 DLTGGGLGSALFSGPASALVSLP------------SSSSTIEDGLHDVRKNYHVVILKHVQAIFA 1767
                             .:.|:|            |....||  ..||.:::
  Rat   228 -----------------PVTSIPYQLQRLFVLLQTSKKRAIE--TTDVTRSF------------- 260

  Fly  1768 HLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGS 1832
              |..:.:      .|             :|.|..|....:.::|::..|...|..|:|....|.
  Rat   261 --GWDSSE------AW-------------QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGK 304

  Fly  1833 FSDQKICQECPHRYSKEEPFSVFSVDIRNH------SSLTESLEQYVKGELLEGADAYHCDKCDK 1891
            ..|...|.||.:...:.:.:....:.||.:      :|:.|:|..:::.|:|:|.:.|.|::|.|
  Rat   305 LKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKK 369

  Fly  1892 KVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDM----------EPYTVS- 1945
            |....|.:.....|.:|.:|||||::||..:..||.||...||..|||          .|.|.|
  Rat   370 KCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMSFPEELDMSTFIDIEDEKSPQTESC 434

  Fly  1946 --------------------------------------------GLAKLE-GEVVEVGDNCQTNV 1965
                                                        ||.|:| .|..:..|:.|..:
  Rat   435 TDSGAENEGSCHSDQMSNDFSTDDAVDEGICLESSTGSEKISKPGLEKVEMAETDQRKDSIQFQL 499

  Fly  1966 ---ETTKYELTGIVVHSGQASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAECF 2027
               .:..|||..::||||.|:||||::.|.|.:..    |||.|:|..|:..   ..|::| :..
  Rat   500 GEPNSLMYELFSVMVHSGSAAGGHYYACIKSFSDD----QWYSFNDQHVSRI---TQEDIK-KTH 556

  Fly  2028 GGE-----YMGETYDNNLKRMQYRRQKRWWNAYMLFY-----TR------CDQTP------VQYE 2070
            ||.     |....:.::.            |||||.|     ||      .|:.|      ||.|
  Rat   557 GGSSGSRGYYSSAFASST------------NAYMLIYRLKDPTRNAKFLEVDEYPEHIKNLVQKE 609

  Fly  2071 PSVEQLSLAESRNMVLPLPKPIERSVRHQNIRFLHSRSIFSVEFFNFIKKLVSCNLLSARSNKIT 2135
            ..:|:   .|.|.      :.|||:.....:..||.           :|:::..|.|....:|..
  Rat   610 RELEE---QEKRQ------REIERNTCKIKLFCLHP-----------VKQVMMENKLEVHKDKTL 654

  Fly  2136 PAAEELSLLGVQLASQFLFHTGFRTKKSLRGPVMEWYDALSHHIRSSALVRKWFANHALLSPPSR 2200
            ..|.|::...:.|............|          ||....::..|
  Rat   655 KEAVEMAYKMMDLEDVIPLDCCRLVK----------YDEFHDYLERS------------------ 691

  Fly  2201 LGEYILMAPSPDVRTVFVKLVVFFCHFAINDEPLTGYDGANLCEQVLISVLRLLKSEAADYGKHL 2265
                                                |:|                .|....|..|
  Rat   692 ------------------------------------YEG----------------EEDTPMGLLL 704

  Fly  2266 PHYFSLFSMYVGLGTREKQQLLR------LNVPLQFIQVALDDGPGPAIKYQY-----PEFSKLH 2319
            ....|.:...:.|.||:..|:.:      :.|.:..:.:..:....|.....|     .||.:|.
  Rat   705 GGVKSTYMFDLLLETRKPDQIFQSYKPGEVMVKVHVVDLKAETVAAPVTVRAYLNQTVLEFKQLI 769

  Fly  2320 QVVSHL----IRCSDVSEKCQSSNQNARPLSNPFKDPNVAHEELTPLSTECMDLLFNRTGYIKKV 2380
            ...:||    :|.  |.|:|.:   :.|.||.|.|          .|..|.    |.|:.  |..
  Rat   770 SKATHLPAEPMRI--VLERCYN---DLRLLSMPSK----------TLKAEG----FFRSN--KVF 813

  Fly  2381 IEDTNVGDEGLKLLQYCSWENPHFSRAVLTELLWQCGFAYCHDMRHHTDLLLNILLIDDSWQHHR 2445
            :|.:...|           ....|:.:.|.:||          .||...:.|.:||.:.|
  Rat   814 VESSETVD-----------HQAAFTDSHLWKLL----------DRHANTIRLFVLLPEQS----- 852

  Fly  2446 IHNALNGVAEEREGLLETIQRAKTHYQKRAYQIIKCLTQLFHKSPIALQMLHTNSNITRHWSIAV 2510
                 .|...:|           |.|||..                     ..:.|:
  Rat   853 -----PGSYSKR-----------TAYQKAG---------------------GDSGNV-------- 872

  Fly  2511 EWLQGELDRQRGIGCQYNSYSWSPPAQSNDNTNGYMLERSQSAKNTWSMAFELCPD----EVSEK 2571
               ..:.:|.:|            ||.|..:.:..:.|.::..|   |::.:...|    :.|:.
  Rat   873 ---DDDCERAKG------------PAGSLKSVDAILEESTEKLK---SLSLQQQQDGDNGDSSKS 919

  Fly  2572 TDENNEPNLETNMDENKSEPVAQPGGVLEGSTGGTEQLPENKTPTTSSPSTAAWPARGDSNAIPR 2636
            |:.::..|:|:.::|             .||:...:.....:...||.|.......|.||:.
  Rat   920 TETSDFENIESPLNE-------------RGSSTSVDNRELEQHIQTSDPENFQSEERSDSDV--- 968

  Fly  2637 LSRQLFGAYTSTGSGSTSGGSAPTSALTTTAGSGANSETESSAQETTGETTINGLTNSLDQMEIT 2701
                       ....|||           :..|...|.:.||......::....|.|.||...||
  Rat   969 -----------NNDRSTS-----------SVDSDILSSSHSSDTLCNADSAQIPLANGLDSHSIT 1011

  Fly  2702 AKKKCRRVIIKKLVESKDEEDATT 2725
            :.::.:....||......|||:.|
  Rat  1012 SSRRTKANEGKKETWDTAEEDSGT 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	114/490 (23%)
		UCH	1668..2059	CDD:278850	110/472 (23%)
Usp47	XP_006230106.1	peptidase_C19C	186..586	CDD:239124	112/479 (23%)
		UCH	187..581	CDD:278850	110/473 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900