Protein Alignment faf and ubp15

DIOPT Version :10

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: NP_595341.1
• Gene: ubp15 / 2541131
• PomBaseID: SPBC713.02C
• Length: 1129
• Species: Schizosaccharomyces pombe
• Alignment Length: 1184
• Identity: 247/1184 - (20%)
• Similarity: 421/1184 - (35%)
• Gaps: 324/1184 - (27%)

  Fly  1408 EALEV-LTISFILNPSANEALTSDPNWPKFITSIVLKNPLRHVRQVASEQLFLASTYCAGDRRPF 1471
            :|.|| :..|..|..|:.|.|.:| |:.:...|:|...|.......||....:.:.....|
pombe     7 DAEEVNMDSSMELEESSQEPLRAD-NYEEIYNSLVHHEPDLEEAAHASYSWVVKNFSTLED---- 66

  Fly  1472 VYMVNLLVGALKTLVPQYESTCAEFFSVL----CRTLSYGCIYNWPLQISEGLLGDEIKWLQRIR 1532
                       ||..|.:::....:..||    |....|..::      .|.|...:::.:::..
pombe    67 -----------KTYSPLFKAGHTTWRIVLFPKGCNQTEYASVF------LEYLPQCKVEAIRKYE 114

  Fly  1533 ENVHATGDTQVHEELL--EGHLCLAKELMFFLGADSKA--QLNELIHEL---IDDFLFTASREFL 1590
            ..:.|.....:..|::  |.:.|.|:..:.........  |:|...|..   :.|:.||
pombe   115 AELAAGKTPTIDPEIVNDETYSCCAQFALSLSNVQDPTVMQINTSHHRFRSEVKDWGFT------ 173

  Fly  1591 HLRRHGSLRQDTVPPPVCRSPHTIAAACDLLIALCQLCVPNMKLLTNTLIDFVCTDT------DP 1649
               |...||:..||.|                   :..||   .|.|   |.:|...      ||
pombe   174 ---RFVDLRKIAVPTP-------------------EFPVP---FLEN---DEICISVTVRVLQDP 210

  Fly  1650 LRE-WDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGD 1713
            ... |.......::...|:.||||.||||||||:||.|:.....|..:.:    ..||.:|
pombe   211 TGVLWHSFVNYNSKKETGYVGLKNQGATCYMNSLLQSLFFTNIFRKTVYK----IPTDNDD---- 267

  Fly  1714 SDLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYV 1778
                                 |..|.:..::...:::.|....|....:...|.
pombe   268 ---------------------SRDSVAYALQRVFYNLEKQREPVSTTELTRSFG----------- 300

  Fly  1779 PRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGSFSDQKICQECP 1843
                |..|...       .|.|..||...|.::|::.:|.......:|....|.......|.:..
pombe   301 ----WNSFDSF-------MQHDIQEFNRVLQDNLEKKMKGTEVENALNDIFVGKMKSYVKCIDVN 354

  Fly  1844 HRYSKEEPFSVFSVDIRNHSSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVL 1908
            :..|:.|.|....::::...:|.:|....::.|.|.|.:.|:.:....:... |.:..:.||.||
pombe   355 YESSRVEDFWDIQLNVKGMDTLEDSFRDAIQVETLTGDNKYYAEGHGLQDAH-KGIIFESLPNVL 418

  Fly  1909 AIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELT 1973
            .:|||||:||..|...:|.||..|||..:|:|||           :.|..|..:::|    |.|.
pombe   419 QLQLKRFDYDMLRDMMVKINDRHEFPLEIDLEPY-----------LSETADKSESHV----YVLH 468

  Fly  1974 GIVVHSGQASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGET--Y 2036
            |::||.|...||||::.|..:..:|    |:||||..||...:   :|:..:.:|||..|..  |
pombe   469 GVLVHGGDLHGGHYYALIKPEKDSN----WFKFDDDRVTRATI---KEVLEDNYGGEPAGRAKGY 526

  Fly  2037 DNNLKRMQYRRQKRWWNAYMLFY---TRCDQ--TPVQYE--PSVEQLSLAESRNMVLPLPKPIER 2094
            :.|       ..||:.|||||.|   :|.|.  :||..|  |...:.:|.|...:|       ||
pombe   527 NGN-------PFKRFMNAYMLVYFRKSRLDHILSPVTAEDVPFHVRNTLDEEHRVV-------ER 577

  Fly  2095 SVRHQNIRFLHSR-SIFSVEFFNFIKKLVSCNLLSARSNKITPAAEELSLLGVQLASQFLFHTGF 2158
            .:..:..:.::.| .:.:.:.|   ||....::....::...|.               |..|..
pombe   578 KLLEREEQQIYRRVRVLTTDGF---KKYHGFDMTDFSASDDDPV---------------LITTKI 624

  Fly  2159 RTKKSLRGPVMEWYDALSHHI-----RSSALVRKWFANHALLSPPSRLGEYILMAPSPDVRTVFV 2218
            :...::      |  .|..|:     |.::.:|.|...       :|....:.:....|.:|:.|
pombe   625 KRNANI------W--DLQKHLAGLLNRDTSGIRIWLMT-------NRQNRTVRVDLPLDKKTILV 674

  Fly  2219 KLVVFFCHFAINDEPLTGYDGANLCEQVLISVLRLLKSEAADYGKHLPHYFSLFSMYVGLGTREK 2283
            ..:   |...|..:         :..:|.:..|.......||:|....:.|..: :::.:...|.
pombe   675 DQI---CDMHIRKD---------MDMRVYVEFLSEHNQLLADFGATDDNDFDTY-IFLKIFDYET 726

  Fly  2284 QQLLRL-------NVPL----QFIQVALDDGPGPAIKYQYPE--------------FSKLHQVVS 2323
            ||:..|       |.|:    ::|:..|.......|.| |.|              |.|....|.
pombe   727 QQISGLADLHVSKNSPISSLSEWIREHLKWSSDVPITY-YEEIKTGMVDVLDPNASFEKSEIQVG 790

  Fly  2324 HLIRCSDVSEKCQSSNQNARPLSNPFKDPNVAHEELTPLSTECMDLLFNRT--GYIKKVIEDTNV 2386
            .:| |.:......||:..    |:|:|.           :.:..|.:.:|.  .:..:..:|||.
pombe   791 DII-CFEKKLVHDSSSDT----SHPYKS-----------ALDLYDFMAHRVVITFEPRYSDDTNN 839

  Fly  2387 GDEGLKLLQYCSWENPHFSRAVLTELLWQ---CGFAYCH------------------------DM 2424
            |...|.|..:.::.:  .:|||..:|...   ..|...|                        ..
pombe   840 GVFDLVLTTHTNYTD--MARAVANKLNVDPNYLQFTMAHLPSRTPRSVIRNPSKFTLQNAIPSTY 902

  Fly  2425 RHHTDLLLNILLID------DSWQHHRIHNALNGVAEE--------REGLLETIQRAKTHYQK-- 2473
            .|:.::::...::|      :..|..|:|...||::.|        :||.:|.|.|..|  ||
pombe   903 SHNQNVVMFYEVLDITLSELERKQLIRVHFLSNGISHETQMEFYVDKEGTVEDILRQVT--QKVP 965

  Fly  2474 ---------RAYQI 2478
                     |.|::
pombe   966 LNAEDASRLRLYEV 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	Ubl1_cv_Nsp3_N-like	<994..1060	CDD:475130
		peptidase_C19C	1666..2064	CDD:239124	107/402 (27%)
		DUF3517	2198..2566	CDD:463438	66/360 (18%)
ubp15	NP_595341.1	COG5077	13..1129	CDD:227409	244/1178 (21%)