Protein Alignment faf and math-33

DIOPT Version :9

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: NP_001294689.1
• Gene: math-33 / 179538
• WormBaseID: WBGene00010406
• Length: 1138
• Species: Caenorhabditis elegans
• Alignment Length: 1036
• Identity: 223/1036 - (21%)
• Similarity: 353/1036 - (34%)
• Gaps: 348/1036 - (33%)

  Fly  1627 LCVPNMKLLTNTLIDFVCTDTDPLREWDYLPPVGA-------RPTKGFCGLKNAGATCYMNSVLQ 1684
            ||.|....:.|..|...|..|..:       |.||       |.| |..||:|.||||||||:||
 Worm   156 LCNPKDGYVVNDTIKLRCRFTADV-------PTGANYMWDSKRHT-GCIGLRNQGATCYMNSILQ 212

  Fly  1685 QLYMVPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHD 1749
            ..|.....|..:             ::.|       :|:.            |:.|:
 Worm   213 SFYFTTGFRRAV-------------YNMD-------VGTE------------PNESN-------- 237

  Fly  1750 VRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDE 1814
                    |:..:|.:|..| ..|.:......|...|.  .:.::...|.|..||...||::|:.
 Worm   238 --------IVLAMQRVFYEL-QMASEAVETNSLTRAFG--WDKLDAFNQHDVQEFCRVLLDNLET 291

  Fly  1815 GLKALGQPQLMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLTESLEQYVKGELLE 1879
            .:|...:.:.:.....|:......|.:..:..|:.|.|....:::....||..:.|.|...|:|:
 Worm   292 KMKGTSEEKSIPNLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFEAYTTSEILD 356

  Fly  1880 GADAYHC-----DKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAI--KFNDYFEFPRIL 1937
            ..:.|..     .:.:|.|..|      :|||:|.:||.||:|     |.:  |.|:.|.||
 Worm   357 DENKYDAGDHGLQRAEKGVKFV------ELPPILHVQLMRFQY-----CGVEQKINERFSFP--- 407

  Fly  1938 DMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELTGIVVHSGQASGGHYFSYI---LSKNPAN- 1998
              |...::...:|...:.|         |...|.|..::||||:..||||.:||   |.::..:
 Worm   408 --EKMNLASCCELGPMLTE---------EDCVYSLHAVLVHSGEFHGGHYVTYINVNLHESAVDP 461

  Fly  1999 -GKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYDNNLKRMQYRRQKRWWNAYMLFYTR- 2061
             ...:|.||||..|:  :...|:.:.:. ||||          |.|..       :||||.|.|
 Worm   462 TSSAKWCKFDDDVVS--RTTTDDAIVSN-FGGE----------KTMNS-------SAYMLVYVRD 506

  Fly  2062 --CDQ--TPV---QYEPSV-------------EQLSLAESR---NMVLPLP---------KPIER 2094
              .||  .|:   |...||             |:..|.|.:   .:||..|         ..:::
 Worm   507 NAIDQFLAPIPDSQIPQSVSRTFEMERLHRNREKKKLEEEQLCMGIVLVTPDIVASNHSFDLVDQ 571

  Fly  2095 SVRHQNIRFLHS---RSIFSVEFFNFIKKLVSCNLLSARSNKITPAAEELSLLGVQLASQFLFHT 2156
            |:.|.:|.  |.   :.:|:.|.:.|:.     :.|..:|     |.:::.:......::.....
 Worm   572 SIVHDSIP--HETVWKHMFTAELYQFVH-----DRLFEKS-----AMQKIDMFDSDDEARQARRD 624

  Fly  2157 GFRTKKSLRGPVMEW-----------YDALSHHIRSSALVRKWFANHALLSPPSRLGEYILMAPS 2210
            ..|..||.:.....|           ...|:..:|.|..:.        ....:||...:    |
 Worm   625 NLRRIKSKKFNFRLWRMTDSYSLERTTQKLTSRLRPSEFID--------CKTDTRLDTLL----S 677

  Fly  2211 PDVRTVFVKLVVFFCHFAIN-DEPLTGYDGANLCEQVLISV---------LRLLKSEAADYGKHL 2265
            .|..|::|:       |:.| :.||..||.|   ..:|..|         ..::.....|..|..
 Worm   678 QDFETIYVE-------FSNNIERPLCEYDTA---RDLLFFVKYYDTMTDKFTIIGHTMFDCHKRF 732

  Fly  2266 PHYFSLFSMYVGLGTREKQQLLRLNVPLQFIQVALDDGPGPA---IKY------QYPEFSKLHQ- 2320
            ..|.|:....:||                           ||   :||      .|.|...|.|
 Worm   733 NLYRSMLCEMIGL---------------------------PADTELKYYMEHAASYLELVDLTQN 770

  Fly  2321 -VVSHLIRCSD----VSEKCQ--SSNQNARPLSNPFKDPNVAHEELTPLSTECMDLLFNR----- 2373
             .:..|:...|    |.||.:  :|.|||:...|         |....:..|.:...:|:
 Worm   771 YSIGRLVEEQDGGILVVEKVETSTSTQNAKQKMN---------ELFLDVEVEFVQSFYNKKPEEE 826

  Fly  2374 --TGYIKKVIEDT---NVGDE-GLKL----LQYCSWE-------NPHFSRAVLTELLWQCGFAYC 2421
              ..::|::..|.   .|.:| |.:|    .:...|.       .|.|...:|..         |
 Worm   827 PFEQFVKRICLDDKLFTVAEEIGARLNVDPKKVLIWTRVSGSRFEPFFDDYMLNT---------C 882

  Fly  2422 --------HDMRHHTDLLLNILLID---DSWQHHRIHNAL-----NGVAEE------REG-LLET 2463
                    ||.|.:....:...::.   |....|||...|     ||..||      :|| :::.
 Worm   883 KGLMTRPVHDPRAYKRYRVQYAIMPFDIDEISKHRIQTKLFWQLPNGHVEELTLFPLKEGTVIDI 947

  Fly  2464 IQRAKTHY---------------------QKRAYQI------IKCLTQLFHKSPIALQMLH 2497
            |..||.:|                     .:|.|||      |..|.|......::.|.||
 Worm   948 INEAKRYYPFVEGGSGKFRLLQIGAPPLSNQRVYQIYGENTLISDLDQRTMYKLVSSQALH 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	101/412 (25%)
		UCH	1668..2059	CDD:278850	98/402 (24%)
math-33	NP_001294689.1	COG5077	4..1136	CDD:227409	223/1036 (22%)
		MATH	30..182	CDD:295307	8/32 (25%)
		peptidase_C19C	194..507	CDD:239124	101/408 (25%)
		USP7_ICP0_bdg	636..863	CDD:289221	52/284 (18%)
		USP7_C2	900..1125	CDD:291217	25/109 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910