|
Fly 50 TVANSSLPGGGSGSLDGNQDQQPATDSQSSDDVAASLSANSVDSTITIVPP------------EK 102
|:.....|.|.:.|.....|.||....| .:.:::|.|:|....| .|| |:
Mouse 2 TITTRGSPVGENESQGQTSDGQPQPSFQ-QNQISSSDSSNETSPT---TPPYEQGQGDAPPQHEE 62
Fly 103 LISSFPTTKLRSLTQKISNPRWVVPVLPEQELEVLLNAAIELTQAGVDHDCEPCVEFYRNGLSTS 167
...|||.|.|..|...|:..||||||||:.||||||.|:|:||:.|:|...|.|..|:|:.|:.|
Mouse 63 EDPSFPHTDLAKLEDMINRSRWVVPVLPKGELEVLLEASIDLTKKGLDVKSEACQRFFRDVLTVS 127
Fly 168 FAKILTDEAVNSWKNNIHHCILVSCGKLLHLIAIHMQRDNPYLLDLLAIVFDPENKFNTFNAGRQ 232
|:|||.||||:.||..||.||:.:..:|:.|....:.:|....|:||||..:|..||:.:|..|.
Mouse 128 FSKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPFLELLAIALNPHCKFHVYNGARP 192
Fly 233 PECFAAPDYIWGQLDSNKMYARPPPEPKNARGWLVDLINRFGQLGGFDNLLERFNIGLELLKRNQ 297
.|..::. .|...::::| ..|:..:.:||||||||.||.|.||..|.:||..|
Mouse 193 CESVSSS----VQFPEDELFA-CSPDLHSPKGWLVDLINTFGTLNGFQILHDRFTSG-------- 244
Fly 298 NKCTGKNISVEGRVENGAQDNRLTLALIHSLLRPFGQCYELLMPATIAKYFMPTWNVVLDLLDSF 362
:.|.:..|.:|::|||||||.|...|:.|||:|...||..:|...
Mouse 245 --------------------SALNVQTIAALIKPFGQCYEFLTQHTLRKYFIPVIEVVPQILQKL 289
Fly 363 TDEELKREVKPEGRNDYINGIVKSARLLASRLTGQEELIRDLEMFRLKMILRLLQVSSFNGKMNA 427
|:||||:|.|.|.:||.|:.|:|..:.||||:.||||.:::||.|||||||||||:|||||||||
Mouse 290 TNEELKKETKTEVKNDTISMIIKFLKNLASRIPGQEETVKNLETFRLKMILRLLQISSFNGKMNA 354
Fly 428 LNEINKVLSSVAYFSHRSQPLPHCMPEDEMDWLTADRMAQWIKSSDVLGVVLKDSLHQPQYVEKL 492
|||||||||||:|::| .|...|:| |||.:||.:||:.:::|.:||:|||||||||||:
Mouse 355 LNEINKVLSSVSYYTH-----GHGNSEEE--WLTVERMTEWIQQNNILSIVLQDSLHQPQYVEKI 412
Fly 493 EKIIRFLIKEQALTLDDLDAVWRAQAGKHEAIVKNVHDLLAKLAWDFTPEQLDHLFEAFQASMTT 557
|||:||:|||:||||.||:.:|.||||||||||||||||||||||:|:||||||||:.|:||.|.
Mouse 413 EKILRFVIKEKALTLQDLNNIWAAQAGKHEAIVKNVHDLLAKLAWNFSPEQLDHLFDCFKASWTN 477
Fly 558 ANKRQRERLLELIRRLAEDDKNGVMAQKVLKLFWTLAHSQEVPPEVLDQALGAHVKILDYSCSQE 622
|:|:|||:|||||||||||||:||||.|||.|.|.||||.:||.:::|.||.||:|||||||||:
Mouse 478 ASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQD 542
Fly 623 RDAQKTIWLDKCVDELKSGDGWVLPALRLIRDICCLYDTTTNHAQRTQTSTN---RQQVIERLQN 684
||.||..|:|..::|.::.:.||:|||:.|::||.|:.....:..:|..|.. |..:|.:||:
Mouse 543 RDTQKIQWIDCFIEEFRTNNKWVIPALKQIKEICSLFGEAPQNLSQTHQSPRVFYRHDLISQLQH 607
Fly 685 DYSLVILVTNSLTAYMEKVRQMVTDSPGLDATRILIDGRFPHHVQIAERLEFLKFLLKDGQLWLC 749
:::||.||..:|.|||..:|....|....|...:.:..|:.|..::.|||.||:|||||||||||
Mouse 608 NHALVTLVAENLAAYMNSIRLYARDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLC 672
Fly 750 ADQAKQIWHCLAVNAVFPADREECFRWFGKLMGEEPDLDPGINKDFFENNILQLDPHLLTESGIK 814
..||||||:|||.|||:.:|||.||.|:.||||:||||.|.|||:|||:|:|||||.||||:|:|
Mouse 673 VSQAKQIWNCLAENAVYFSDREACFMWYSKLMGDEPDLHPDINKEFFESNVLQLDPSLLTENGMK 737
Fly 815 CFERFFKAVNSKEDKLKAIHRGYMLDNEDLIGKDYLWRVITTGGEEIASKAIDLLKEVSTALGPR 879
|||||||.||.:|.||....:.||:|:.||||.||||:|:....::|:|:|||||||:.|:|||:
Mouse 738 CFERFFKTVNCREGKLMIKRKIYMMDDLDLIGLDYLWKVVIQSNDDISSRAIDLLKEIYTSLGPK 802
Fly 880 LQENIAEFHEMFIGECCSRLRTHYGNIVILGKTQLQEELDAPDQSDNTNDESKDSKMRFI--EAE 942
||.|....||.||..|..||:..|..:.:| |..||:..... ||.
Mouse 803 LQANQVVIHEDFIQSCFDRLKASYDTLCVL-------------------DSEKDNIFSCARQEAI 848
Fly 943 KMCRILKVLQEYVKECDRSFSGDRVHLPLSRVTRGKNTILYIRFQNPGRSIDDMEIVTHSNETMA 1007
:|.|||.||:||:.|.|..:..:|:.||:||..|||:....:||.|.|:.::|::|::|:|.|:.
Mouse 849 RMVRILTVLREYISEYDSDYHEERMILPMSRAFRGKHLSFTVRFPNQGKEVEDLDILSHTNATIG 913
Fly 1008 AFKRNLLKRIKGTSTANIKVDLFYANDEMIGVSDEINPLYQYTIRDKMNLTAKLTPVGTGLASSP 1072
:.:|.:|.|: ..:.|:.|::||... |::...|:...:.|..::||..:|||...:.:.:.|||
Mouse 914 SVRRCILNRM-NVNVAHTKIELFIGG-ELVASEDDRKLVEQLNLKDKSLITAKFIQINSNMPSSP 976
Fly 1073 DSSSDSSTGSPPRPC----PDMQRVESESTLPGVIISQNYQYTEFFLKLYQLGSDLEHGRLRDSA 1133
|||||||.|.|.... .|:...|.|..|||||:|...:|..|..::..|||.|....|||.|
Mouse 977 DSSSDSSAGPPGNHSHNNYRDVSNPEMEKCLPGVIMSLQPRYISFLWQVADLGSMLTVPTLRDGA 1041
Fly 1134 KVLLHLLPCDRQTIRQLKIMCKVPKAAVTVAVTGDKIAKDEEEKLYPTEQAGIEDEEEHCTPEQM 1198
::|:.|:|.|..|:.||:.:| ::...:.:.....:...:
Mouse 1042 RILMKLMPPDSTTLEQLRALC--------------------------SDHVNLGERRLGQSLHSL 1080
Fly 1199 FLHPTPAQVLYNLSVLHGLLIPALDPLGESALLVQSAWMHSGCAHFVLELLTKNNFLPSADMHTK 1263
|...:.:||||...|::.||:||..||.:.:...|..::.||....||.:|.:|||||:.|:.|:
Mouse 1081 FFGSSASQVLYLTEVVYTLLMPAGAPLADISSDFQYHFLKSGGLPLVLSMLIQNNFLPNTDVETR 1145
Fly 1264 RASFQCVLRLAKLFLYIVG----SVLSRV------GDEPMICDLDNGSRSQVDILKQNFSTMPS- 1317
|.::...|::|||.|.||| ..::.. |.:|. ..::..:..|..:|:....::|:
Mouse 1146 RDAYFSALKIAKLLLTIVGYGHVQAIAEACQPVADGTDPK-TPINQVTHDQAVVLQNALQSIPNP 1209
Fly 1318 SSQGTLRAISAKLAVILAREMLSASPEGDRCRTLFSSTLQWSCPDISTIKAVVQLAWASSCGNLQ 1382
||:..||.:|..|| :.:|. |.|..: |||..|:|:.::.||:.||:|:
Mouse 1210 SSECMLRNVSVHLA-----QQISG---------LASRYI----PDICVIRAIQKIIWAAGCGSLE 1256
Fly 1383 ALGNSSGDFED------------EVIVPDGQDFSMCKEALEVLTISFILNPSANEALTSDPNWPK 1435
.:.:.:.|..: || :|..:|.|||||:|:.|.|.|:|.::|..:..|..
Mouse 1257 LVFSPNEDITETYKMTTSTRSNLEV-----KDEQVCCEALEVMTLCFALIPTAMDSLNKEKAWQS 1316
Fly 1436 FITSIVLKNPLRHVRQVASEQLFLASTYCAGDRRPFVYMVNLLVGALKTLVPQYESTCAEFFSVL 1500
|:..::|..|.:.|||:|.||.||..|.|....||.::.:.||...|.....:.......:|::|
Mouse 1317 FVIDLLLYCPSKTVRQLAQEQFFLICTRCCMGHRPLLFFITLLFTILGGAANEKGKHSDVYFTLL 1381
Fly 1501 CRTLSYGCIYNWPLQIS--EGLLGDEIKWLQRIRENVHATGDTQVHEELLEGHLCLAKELMFFLG 1563
.|.|:|. ||..:|:. :.||.|||.||:|:|:.:..||:|.|.:.:|||||.:.|||:.|..
Mouse 1382 RRLLTYA--YNSNIQVPNVDVLLNDEIDWLKRVRDYIKNTGETNVEDPILEGHLGVTKELLSFQS 1444
Fly 1564 ADSKAQLN------ELIHELIDDFLFTASREFLHLRRHGSL--RQDTVPPPVCRSPHTIAAACDL 1620
.:.|..:. .|:.||||.|:|.||:.:|...|.|.| :|.. |||.||.||.|..:|
Mouse 1445 PEKKYHIGCKTGGANLVKELIDYFIFPASKAYLQYMRSGELPIKQAI---PVCGSPATINAGFEL 1506
Fly 1621 LIALCQLCVPNMKLLTNTLIDFV-----CTDTDPLREWDYLPPVGARPTKGFCGLKNAGATCYMN 1680
|:||...||.|:|.:.|.|.:.. .|..:.:.||:||||||.||.|||.||||||||||||
Mouse 1507 LVALAFGCVRNLKQIVNCLTELFYIGTPVTTCEAVGEWEYLPPVGPRPPKGFVGLKNAGATCYMN 1571
Fly 1681 SVLQQLYMVPAVRVGILRAHGA-ATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLP------S 1738
||:|||||:|::|..||..... :.||.:.|.|:...:...: .|...:...| .
Mouse 1572 SVIQQLYMIPSIRNSILAIDSIWSDTDDDIFKGEKQDSENNV------DPRDDVFRYPHQFEDKP 1630
Fly 1739 SSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVE 1803
:.|.:|| ||.|::.:|||:|..|.||..|.||||||:|.|..|:|.|||||||||.||:|
Mouse 1631 TLSKVED-----RKEYNIAVLKHLQITFGHLAASQLQYYVPKGFWQQFRLWGEPVNLREQHDALE 1690
Fly 1804 FFMSLLESLDEGLKALGQPQLMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLTES 1868
||.||::||||..||||.|.:::..|||||:||||||.|||||..||.|:..:||||||.:|.:|
Mouse 1691 FFNSLVDSLDEAFKALGYPTVLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDS 1755
Fly 1869 LEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEF 1933
|||||||:|||||:||||:||||||.||||:.:||||.||.||||||:||:||.|||||||||||
Mouse 1756 LEQYVKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPSVLTIQLKRFDYDWERECAIKFNDYFEF 1820
Fly 1934 PRILDMEPYTVSGLAKLEGEVVEVGDNCQTNV------------ETTKYELTGIVVHSGQASGGH 1986
||.||||||||:|..||||:.| |.||.: .:|||.|.|::||||||:|||
Mouse 1821 PRELDMEPYTVAGATKLEGDSV----NPQTQLIKQNEQSESVIPGSTKYRLVGVLVHSGQANGGH 1881
Fly 1987 YFSYILSKNPANGK-CQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYDNNLKRMQYRRQKR 2050
|:|||:.:|..:.| ..|:|||||:||||||.:|||||.:|||||||||.:|:.:|||.||||||
Mouse 1882 YYSYIIQRNGKDSKRSHWFKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKR 1946
Fly 2051 WWNAYMLFYTRCDQTPVQYE--PSVEQLSLAESRNMVLPLPKPIERSVRHQNIRFLHSRSIFSVE 2113
|||||:|||.|.|.|....| ..:.:|:......::.| .|||||..||::|||::..||:|
Mouse 1947 WWNAYILFYERMDITDEDDEIITYISELTFTRPHQIMSP---AIERSVWKQNVQFLHNQMQFSLE 2008
Fly 2114 FFNFIKKLVSCNLL----SARSNKITPAAEELSLLGVQLASQFLFHTGFRTKKSLRGPVMEWYDA 2174
:|.|||||::||.: :...:.:.|.||:::::.:||||:|||.|||.|||.:|||..:||||
Mouse 2009 YFQFIKKLLTCNAVYLSPAPGQDHLLPEAEDITMISIQLASRFLFTTGFHTKKIIRGPANDWYDA 2073
Fly 2175 LSHHIRSSALVRKWFANHALLSPPSRLGEYILMAPSPDVRTVFVKLVVFFCHFAIND----EPLT 2235
|...:|.|..||.||.::.|.:..:|..||:|..||.::|..|.||:||..||::.| .|.|
Mouse 2074 LCILLRHSKNVRFWFVHNVLFNVSNRFSEYLLECPSAEIRGTFAKLIVFIAHFSLQDGSSPSPFT 2138
Fly 2236 G-----------YDGANLCEQVLISVLRLLKSEAADYGKHLPHYFSLFSMYVGLGTREKQQLLRL 2289
. ||..:|.:.:|.:||.||:.|.:::|:||..||:||.||..||..||.|||:|
Mouse 2139 SPFANPGPYSQIYDNLSLSDHLLKAVLSLLRREVSEHGRHLQQYFNLFIMYASLGLAEKTQLLKL 2203
Fly 2290 NVPLQFIQVALDDGPGPAIKYQYPEFSKLHQVVSHLIRCSDVSEKCQSSNQNARPLSNPFKDPNV 2354
|||..|:.|:||:||||.:||||.|.||||.|||.||||..||.:.|||.....||.|||.|||:
Mouse 2204 NVPATFMLVSLDEGPGPPVKYQYAELSKLHSVVSQLIRCCSVSSRMQSSINGNPPLPNPFGDPNL 2268
Fly 2355 AHEELTPLSTECMDLLFNRTGYIKKVIEDTNVGDEGLKLLQYCSWENPHFSRAVLTELLWQCGFA 2419
: :.:.|:.....|:||.||.|:||||||.:..::.:|||.:|.||||.||.:||:|||||...:
Mouse 2269 S-QPIMPIQQNVADILFMRTTYMKKVIEDCSNSEDTVKLLLFCCWENPQFSCSVLSELLWQVAHS 2332
Fly 2420 YCHDMRHHTDLLLNILLIDDSWQHHRIHNALNGVAEEREGLLETIQRAKTHYQKRAYQIIKCLTQ 2484
:.::::.:.||||.|:|.:||||.|||||||.|:..:::||.:|||.:|.|:||||||.||.:..
Mouse 2333 HAYELQPYLDLLLQIILFEDSWQAHRIHNALKGIPNDQDGLFDTIQHSKNHHQKRAYQCIKWMVT 2397
Fly 2485 LFHKSPIALQMLHTNSNITRHWSIAVEWLQGELDRQRGIG-CQYNSYSWSPPAQSNDNTNGYMLE 2548
||:..|:|.|:|..|.::...|:.|:|||..||:|:...| .||...:||||.|||:..|||.||
Mouse 2398 LFNSCPVAYQILQGNGDLKNKWTWAMEWLGDELERKPYSGNPQYTYSNWSPPVQSNETANGYFLE 2462
Fly 2549 RSQSAKNTWSMAFELCPDEVSEKTDENNEPNLETNMDENKS 2589
:|.|||...:.|.:|.|:| :|:.:..:||:.|
Mouse 2463 KSHSAKMKLTKACDLYPEE---------DPDDQDALDEHVS 2494
| 
