Protein Alignment faf and usp28

DIOPT Version :9

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: XP_002937867.3
• Gene: usp28 / 100492386
• XenbaseID: XB-GENE-990711
• Length: 1104
• Species: Xenopus tropicalis
• Alignment Length: 1159
• Identity: 214/1159 - (18%)
• Similarity: 333/1159 - (28%)
• Gaps: 524/1159 - (45%)

  Fly  1646 DTDPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDF 1710
            |...:.:|    ||         ||||.|.||:.::|:|.|:.:|..|   ...|..:.|.
 Frog   129 DLRRIEDW----PV---------GLKNIGNTCWFSAVIQSLFHLPEFR---RLVHSYSITQ---- 173

  Fly  1711 SGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQ 1775
                                |.|....|         .|.::|  :..::.:|.:|..:..|..:
 Frog   174 --------------------SMLEKCQS---------RDEKRN--LAFMQELQCLFTLMVGSNRK 207

  Fly  1776 YYVPRGLWTHFK--LLGEPVNLREQQDAVEFFMSLLESLDEG--LKALGQ------PQLMNATLG 1830
            :..|.......|  .|.|..   :|||..||...||:.|::.  |...|:      ...|.....
 Frog   208 FVDPSPALELLKDAFLSEEA---QQQDVSEFTHKLLDWLEDAFQLTVNGEDPRDKSENPMVQLFY 269

  Fly  1831 GSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLTESLE-QYVKGELLEGADAYHCDKCDKKVV 1894
            |:|.::... |....:|..|.|..:.:.:...|:|.|.|| ..|:||:.....|.......::..
 Frog   270 GTFLNEGFL-EANKAFSNIETFGQYPLQVNGFSNLNECLEAAMVEGEIENMQTAQSARYRQERWF 333

  Fly  1895 TVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTV----------SGLAK 1949
            |       ||||||..:|.|||::.......|.::..|||.|:.|:.:..          |...:
 Frog   334 T-------KLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPEIIYMDRFMYKNKELMRRKHSETRR 391

  Fly  1950 LEG----------------------------------------------EVVE------------ 1956
            |:|                                              |||.
 Frog   392 LKGCIDHLNQKLESYLKYGSGPNRCPLPDMLQYVLEFANTKSAEWCPPTEVVTTSQSATGSTGSL 456

  Fly  1957 ---------VGDN-----------CQ--------------------------------------- 1962
                     ||:|           |:
 Frog   457 DAQPLQNGFVGNNDTETSNDDSPKCESTSSLPPFVGHTVPNDCIPAEDPTHGSDTLEEIRSVAAC 521

  Fly  1963 -----TNVE------------TTK---------------YELTGIVVHSGQASGGHYFSYILSKN 1995
                 |.||            .||               |.|..::||.|||:.|||::||.|
 Frog   522 LQRWRTEVEKDIQDLKDSIASCTKSIEEVFIDQDLSQVPYRLHAVLVHEGQANAGHYWAYIYS-- 584

  Fly  1996 PANGKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYDNNLKRMQYRRQKRWWNAYMLFY- 2059
              :.:|.|.|::|..|||...   ||:..:.:||                   .|..:||.|.|
 Frog   585 --HSRCCWLKYNDVSVTEANW---EELVRDSYGG-------------------MRNASAYCLMYI 625

  Fly  2060 ----------------------------------TRCDQTPVQYE-------PSVEQLSLAE--- 2080
                                              .|.||...::|       |.:|.:..:|
 Frog   626 NNKLPYLIADHEGELEDKINALHPALQCYVQEDNQRFDQEMTEWEEAHSCKIPQIESVGSSESVD 690

  Fly  2081 --SRNMVLPLPKPIERSVRHQNIRFLHSRSIFSVEFFNFIKKLVSCNLLSARSNKITPAAEELSL 2143
              |||......:...||:..::......::..:                      ||..||....
 Frog   691 HPSRNNASLCCEECSRSLSSEHAMIAKEQTALA----------------------ITKTAESYER 733

  Fly  2144 LGVQLASQFLFHTGFRTKKSLRGPVMEWYDALSHHIRSSALVRKWFANHALLSPPSRLGEYILMA 2208
            .||::|              |:.|........|  :..::|..:   ......|.|:|.|..:
 Frog   734 NGVEVA--------------LKEPTKPETGEAS--LSDASLTAQ---EETEPQPSSQLSEVEI-- 777

  Fly  2209 PSPDVRTVFVKLVVFFCHFAINDEPLTGYDGAN----LCEQVLISVLRLLKSEAADYGKHLPHYF 2269
              |.|..:.|:               |..||.|    ||..:...:..:||:.
 Frog   778 --PSVGKILVR---------------TDTDGYNEEMMLCPAMQGVIFAILKAR------------ 813

  Fly  2270 SLFSMYVGLGTREKQQLLRLNVPLQFIQVALDDGP-GPAIKYQYPEFSKLHQVVSHLIRCSDVSE 2333
                                       ||...||| ...:|..:.|:|:|:|:        ...|
 Frog   814 ---------------------------QVFDRDGPEAGLVKAFHEEYSRLYQL--------SKEE 843

  Fly  2334 KCQSSN-----------QNARP-------LSNPFKDPNVAHEELTPLSTECMDLLFNRTGYIKKV 2380
            ...||:           ||..|       |...|.|.|:::.|              |:..|.||
 Frog   844 PSPSSDPRLQHVLIYFFQNKAPDRVIERTLLEQFADKNLSYNE--------------RSISIMKV 894

  Fly  2381 IED--TNVGDEGLKLLQYCSW-ENPHFSRAVLTELL----------WQCGFAY------CHDMRH 2426
            .:.  ..:|.:.:.:.:|..| |:....|.|...||          ||....|      |
 Frog   895 AQAKLREIGPDDMDMKEYQKWHEDYSLFRKVSVYLLTGLELYQNEKWQEALTYLVYAYQC----- 954

  Fly  2427 HTDLLLNILLIDDSWQHHRIHNALNGVAE------EREGLLETIQRAKTHYQKRAYQ-------- 2477
                  |..|:...       .:| ||.|      .|:.||:...:|.|.::....:
 Frog   955 ------NRSLVSSG-------ESL-GVEETLIQLYRRKCLLKLNDKAATLFESSQEEQVSEGISI 1005

  Fly  2478 ----IIKCLTQLFHKSPIALQMLHTNSNITRHWSIAVEWLQGELDRQRGIGCQY 2527
                ||.|:..:|            |:.|:.....|:|       ..|...|.|
 Frog  1006 MNDLIIPCMHLIF------------NNKISEEDLSAIE-------EMRNRWCSY 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	peptidase_C19C	1666..2064	CDD:239124	114/602 (19%)
		UCH	1668..2059	CDD:278850	112/560 (20%)
usp28	XP_002937867.3	UBA_UBP28	1..42	CDD:270540
		UBP14	<138..611	CDD:227532	107/537 (20%)
		Peptidase_C19I	139..625	CDD:239130	112/560 (20%)
		USP28_C	825..1104	CDD:380452	54/276 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910