Protein Alignment faf and usp47

DIOPT Version :10

• Sequence 1: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Sequence 2: XP_031755561.1
• Gene: usp47 / 100036690
• XenbaseID: XB-GENE-5760041
• Length: 1374
• Species: Xenopus tropicalis
• Alignment Length: 891
• Identity: 200/891 - (22%)
• Similarity: 333/891 - (37%)
• Gaps: 256/891 - (28%)

  Fly  1529 QRIRENVHA-TGDTQVHEELLE--GHLCLAKELMFFLGADS---KAQLNELIHELIDDFLFTASR 1587
            :||..|:.| |...|::|::..  |::.....||:..||.:   .|.|:......:.:..|.|.:
 Frog    58 ERITLNLPASTSVKQLYEDVSSKAGYVSGTFSLMWGNGASNMVDMAALDPTPDRTLQEAGFEAGK 122

  Fly  1588 E-FLHLR-RHGSLRQDTVPPPVCRSPHTIAAACDLLIALCQLCVPNMKLLTNTLIDFV------- 1643
            : ||||. ::|.       .|...|..:..|             .:..|..:|...|:
 Frog   123 KNFLHLTDKNGE-------QPQLTSDESGTA-------------DSSGLDDSTQEKFIGPLPREE 167

  Fly  1644 ---CTDTDPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATT 1705
               ||.....:.:.|...:....| |:.||.|...|||:||:||.|:|.|..|..:.:      .
 Frog   168 SVACTSDYVSQNYSYSSLLSKSDT-GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYK------W 225

  Fly  1706 DGEDFSGDSDLTGGGLGSALFSGPASALVSLP------------SSSSTIEDGLHDVRKNYHVVI 1758
            :.|:...|               |.|   |:|            |....||  ..||.:::
 Frog   226 EFEESEED---------------PVS---SIPYQLQRLFVLLQTSKKRAIE--TTDVTRSF---- 266

  Fly  1759 LKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQ 1823
                       |..:.:      .|             :|.|..|....:.::|::..|...|..
 Frog   267 -----------GWDSSE------AW-------------QQHDVQELCRVMFDALEQKWKQTEQAD 301

  Fly  1824 LMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLT------ESLEQYVKGELLEGAD 1882
            |:|....|...|...|.||.:...:.:.|....:.||...|.|      |:|:.:::.|.|:|.:
 Frog   302 LINQLYQGKLKDYVKCLECGYESWRIDTFLDIPLVIRPFGSNTAFGSMEEALQAFIQPETLDGPN 366

  Fly  1883 AYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPY----- 1942
            .|.|::|.:|....|.:.....|.:|.:|||||::||..:..||.||...||..|||.|:
 Frog   367 QYFCERCKRKCDARKGLKFLHFPYLLTLQLKRFDFDYTSMHRIKLNDRMTFPDELDMSPFIDVED 431

  Fly  1943 ---------TVSGLAKLEG--------------EVVEVGDNCQTNVETTK-----------YELT 1973
                     |.|| |:.||              :.|:.|...:||....|           |||.
 Frog   432 EKSPQTDSCTDSG-AENEGSCHSDQMSNDFSTDDAVDEGICLETNSNIEKLNKSVSEKNSLYELF 495

  Fly  1974 GIVVHSGQASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAECFGGE-----YMG 2033
            .::||||.|:||||::.|  |:.|:|  |||.|:|..|:..   ..|::| :.:||.     |..
 Frog   496 SVMVHSGSAAGGHYYACI--KSFADG--QWYSFNDQHVSRI---TQEDIK-KTYGGSTGNRGYYS 552

  Fly  2034 ETYDNNLKRMQYRRQKRWWNAYMLFYTRCDQTPVQYEPSVEQLSLAESRNMVLPLPKPIERSVRH 2098
            ..:.::.            |||||.|..  :.|.:.....|.:...|  ::.|.:.|..|:..:.
 Frog   553 SAFASST------------NAYMLMYRL--KNPARNAKFPEAIEFPE--HIKLLVQKEQEQEEQE 601

  Fly  2099 QNIRFLHSRSIFSVEFF--NFIKKLVSCNLLSARSNKITPAAEELS-----LLGV------QLAS 2150
            :..|.: .|:...::.|  :.:|:::..:.|....:|....|.|::     |.||      :|..
 Frog   602 KRQREI-ERNTCKLKLFCMHPVKQIMMESKLEVHKDKTMKEAVEIAHKLMDLEGVISLDCCRLVK 665

  Fly  2151 QFLFHTGF---------RTKKSLRGPVMEWY--DALSHHIRSSALVRKWFANHAL---------- 2194
            ...||...         ||...|.|.|...|  |.|....|...:.:.:.....:
 Frog   666 YDEFHDYLERSYEDEEDRTMGYLLGGVKSSYMFDLLLETKRPDQVFQSYKPGEVMVKVYVVDLKT 730

  Fly  2195 --LSPPSRLGEYI---------LMAPSPDVRTVFVKLVVFFCHFAINDEPLTGY-------DGAN 2241
              ::||..:..|:         |::.|.|:....:::|:..|:   ||..|...       :|..
 Frog   731 ETVAPPVSVRAYLSQTIIEFKQLISKSVDLLPDTMRVVLERCY---NDLRLLNVANKTLKAEGFF 792

  Fly  2242 LCEQVLISVLRLLKSEAADY---------GKHLPHYFSLFSMYVGL 2278
            ...:|.:.     .|::.||         .|.|..:.:...:||.|
 Frog   793 RSNKVFVE-----SSDSLDYQLVFTDSHLWKLLDRHANTIRLYVSL 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
faf	NP_524612.2	Ubl1_cv_Nsp3_N-like	<994..1060	CDD:475130
		peptidase_C19C	1666..2064	CDD:239124	119/459 (26%)
		DUF3517	2198..2566	CDD:463438	20/106 (19%)
usp47	XP_031755561.1	peptidase_C19C	192..571	CDD:239124	119/461 (26%)
		USP47_C	1124..1362	CDD:466158