Protein Alignment sip3 and rnf145

DIOPT Version :10

• Sequence 1: NP_651894.3
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001072260.1
• Gene: rnf145 / 779713
• XenbaseID: XB-GENE-979193
• Length: 695
• Species: Xenopus tropicalis
• Alignment Length: 442
• Identity: 97/442 - (21%)
• Similarity: 169/442 - (38%)
• Gaps: 122/442 - (27%)

  Fly    43 VIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETC--------LAFTVFRDDFNP 99
            |:::.|:::  :|...:...|....:....|.||..|..::.|.|        |.|||
 Frog   229 VLFMVFWLV--LFALQIYTYFSTRDQPTSRERLLFLFLTSIAECCSTPYSLLGLVFTV------- 284

  Fly   100 RFVALFTVLL---FLKSFHWLAEE-----------------------RVDFMERSPVLGWLFHIR 138
            .||||..:.|   :|:.:.....:                       .:..:.|:.:|..:..|.
 Frog   285 SFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIV 349

  Fly   139 VGSLL-TVLGILD-------------------------YVLLIHAYNSTLVRGPTVQLVFGFEYA 177
            |.|:| ::|.|.|                         ::|:..:|.:.::    .|. |..::.
 Frog   350 VASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPSYMAYMI----CQF-FHMDFW 409

  Fly   178 ILLTVIAS---------TAIKYVLHAAEMRTDTPWENKAVFLLYTELVIGLIKVVLYILFVVIMA 233
            :|:.:.:|         |...|||...|.....|.||....:.|   |.|..:::.:::.:.::|
 Frog   410 LLIIISSSILTSLQVLGTLFIYVLFMIEEFRKEPVENMDDVIYY---VNGTYRLLEFLVALCVVA 471

  Fly   234 KIYALPMFVF------RPMFFTIRNF-----RKAL--NDVIMSRRAIRNMNTLYPDATPEELRQS 285
              |.:...||      ..|...|.::     |..|  ...::.|.|:..:.:| |.||.|:|.|.
 Frog   472 --YGVSETVFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSL-PVATKEQLEQH 533

  Fly   286 DNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTVNSTAMPRQGDEAV 350
            ::||.||.:|| |.:...||.|.||..||:.|...|:|||.|...:      .|.:....|:
 Frog   534 NDICSICYQDM-NSAVITPCSHFFHPGCLKKWLYVQETCPLCHCQL------KSLSQQATGE--- 588

  Fly   351 AAAAGNPIPAAAGVQPAGGVPPPA-----PTAVVDGNQA-----RADVNVAG 392
            :.::.||:...:...|..|....|     |.|.|....|     ..|:.|:|
 Frog   589 SGSSTNPVSEQSATNPPLGPVSRAEVTTEPLAAVPTRSALEQEPTMDIKVSG 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sip3	NP_651894.3	HRD1	20..>365	CDD:227568	87/403 (22%)
rnf145	NP_001072260.1	TRC8_N	8..506	CDD:463960	54/295 (18%)
		RING-H2_RNF145	533..575	CDD:319598	19/42 (45%)
		rad18	537..>651	CDD:273165	33/114 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..610		5/27 (19%)