Protein Alignment sip3 and Rnf139

DIOPT Version :9

• Sequence 1: NP_001263152.1
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_780435.1
• Gene: Rnf139 / 75841
• MGIID: 1923091
• Length: 668
• Species: Mus musculus
• Alignment Length: 406
• Identity: 102/406 - (25%)
• Similarity: 157/406 - (38%)
• Gaps: 86/406 - (21%)

  Fly    31 VVYITKSNASMGVI-YI--------QFFVIVFMFGKLLSKIFL----GTLRAAEFEHLLERFWYA 82
            |.::|:..|...|: ||        .||:....|..::..:.:    .||.......::....:.
Mouse   240 VFWLTRITAQATVLMYILRMANETESFFISWDDFWDVICNLIISGCDSTLTVLGMSAVISSIAHY 304

  Fly    83 LTETCLAF--TVFRDDFNPRFVA--LFTVLLFLKSFHWL-AEERVDFMERS-------------- 128
            |....|||  :...||....|||  ||.:|........| .|||:..:.|:
Mouse   305 LGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLLLTAVLHFIHG 369

  Fly   129 ---PVLGWL-------FH-----IRVGSLLTVLGI-LDYVLLIH-AYNSTLVRGPTVQLVFGFEY 176
               |||..|       ||     :.|.:.|.:|.: |.|||..| |.|:.|.      .|..|..
Mouse   370 MTDPVLMSLSASHVSSFHRHFPVLFVSACLFILPVLLSYVLWHHYALNTWLF------AVTAFCV 428

  Fly   177 AILLTVIASTAIKYVLHAAEMRTDTPWENKAVFLLYTELVIGLIKVVLYILFVVIM--------- 232
            .:.|.||.|..: |.|...:...:..||....::.:......:|:    .:|.|:|
Mouse   429 ELCLKVIVSLTV-YTLFMIDGYYNVLWEKLDDYVYFVRSTGNIIE----FIFGVVMFGNGAYTMM 488

  Fly   233 ----AKIYALPM--FVFRPMFFTIRNFRKALNDVIMSRR-AIRNMNTLYPDATPEELRQSDNICI 290
                :||.|..|  ..:..::..::|..|    ..|:|| |::.:|:| |:.....|::.|::|.
Mouse   489 FESGSKIRACMMCLHAYFNIYLQVKNGWK----TFMNRRTAVKKINSL-PEIKGSHLQEIDDVCA 548

  Fly   291 ICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTV--NSTAMPRQGDEAVAAA 353
            ||..:....::..||.|.||..|||.|...|.|||.|...:.....:  ||.|....|   ..|.
Mouse   549 ICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDEIKDNSNASNNNG---FIAP 610

  Fly   354 AGNPIPAAAGVQPAGG 369
            ..||.|..|..:.|.|
Mouse   611 NENPNPEEALREDAAG 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sip3	NP_001263152.1	HRD1	20..>365	CDD:227568	100/400 (25%)
		zf-RING_2	287..328	CDD:290367	16/40 (40%)
Rnf139	NP_780435.1	TRC8_N	19..516	CDD:290425	64/286 (22%)
		zf-rbx1	<544..586	CDD:289448	17/41 (41%)
		RING	547..589	CDD:238093	17/41 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	602..668		8/28 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6571
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850