DRSC/TRiP Functional Genomics Resources

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Protein Alignment sip3 and CHFR

DIOPT Version :9

Sequence 1:NP_001263152.1 Gene:sip3 / 43747 FlyBaseID:FBgn0039875 Length:626 Species:Drosophila melanogaster
Sequence 2:NP_001154816.1 Gene:CHFR / 55743 HGNCID:20455 Length:664 Species:Homo sapiens


Alignment Length:229 Identity:51/229 - (22%)
Similarity:78/229 - (34%) Gaps:69/229 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   257 LNDVIMSRRAIRNMNTLYPD-----ATPEELRQSDNICIICREDMVNHSKKL-PCGHIFHTTCLR 315
            ||..::..:..||..|::.|     ..|:::.:: ..|||| :|:::....| ||.|.|...|..
Human   268 LNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEET-LTCIIC-QDLLHDCVSLQPCMHTFCAACYS 330

  Fly   316 SWFQRQQTCPTCRL---NILRTPTVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTA 377
            .|.:|...|||||.   .|.:...:|                 |.:.|.....|           
Human   331 GWMERSSLCPTCRCPVERICKNHILN-----------------NLVEAYLIQHP----------- 367

  Fly   378 VVDGNQARADV------NVAGGQALPPNFADLFGDASGLPNGLPNLAGLQIPPPPVMPMISPFMI 436
              |.:::..||      |......|.|.....|.|..|....|..|:.:......:.   .|:::
Human   368 --DKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDIS---QPYVV 427

  Fly   437 -------------PPHFGYLTPLP--PPPIPQDL 455
                         |||    .|.|  .|..||.|
Human   428 CRQCPEYRRQAAQPPH----CPAPEGEPGAPQAL 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sip3NP_001263152.1 HRD1 20..>365 CDD:227568 29/116 (25%)
zf-RING_2 287..328 CDD:290367 16/41 (39%)
CHFRNP_001154816.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
FHA 16..105 CDD:238017
FHA <31..140 CDD:224630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 142..267
RING 303..346 CDD:238093 18/43 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 388..417 7/28 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 439..461 9/23 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5243
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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