Protein Alignment sip3 and amfr

DIOPT Version :9

• Sequence 1: NP_001263152.1
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001017083.1
• Gene: amfr / 549837
• XenbaseID: XB-GENE-923086
• Length: 635
• Species: Xenopus tropicalis
• Alignment Length: 627
• Identity: 138/627 - (22%)
• Similarity: 237/627 - (37%)
• Gaps: 162/627 - (25%)

  Fly    33 YITKSNASMGVIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETCLAFTVFRDDF 97
            |:...:..:.|:......::.:..||:..:..|.||..|.:||.::||        .|..:
 Frog    68 YLVSDSLGVWVLVNTVCCLLMLIAKLIQHVVFGPLRVGERQHLKDKFW--------NFIFY---- 120

  Fly    98 NPRFVALFTV------------------LLFLKSFHWLAEERVDFMERSPVLGWLFHIRVGSLLT 144
              :|:.:|.|                  ||||.....|.::|.:::..||......|:||..||.
 Frog   121 --KFIFIFGVLNVQTVEEVVLWFLWFAGLLFLHLMVQLCKDRFEYLSFSPTTPMSCHMRVLVLLN 183

  Fly   145 VLGILDYVLLIHAYNSTLVRGPTVQLVFGFEYAILLTVIASTAIKYVLHAAEMRTDTPWENKAVF 209
            ::.:....|.:....:....|.........|..::.|......::||:|..::..:..||.|..:
 Frog   184 IMLLACCGLAVLCAIAGYTHGMHTLAFMAAECMLVTTRTTHVVLRYVIHLWDLNHEGTWEGKGTY 248

  Fly   210 LLYTELV-------IGLIKVVLYILFVVIMAKIYALPMFV-FRPMFFTI-RNFRKALNDVIMSRR 265
            :.||:.|       |.|:..:..:||..|...:.:|.:|: .|.:|... |..|:..|.:    |
 Frog   249 VYYTDFVMELSHLSIDLMHHIHMLLFGNIWLSMASLVIFMQLRHLFHEFQRRIRRHKNYL----R 309

  Fly   266 AIRNMNTLYPDATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLN 330
            .:.||...:..||||||..:.:.|.||.:.| ..::||||||:||.:|||||.::..:|||||::
 Frog   310 VVGNMEAHFAVATPEELEANSDDCAICWDSM-QSARKLPCGHLFHNSCLRSWLEQDTSCPTCRMS 373

  Fly   331 I-LRTPTVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARADVNVAGGQ 394
            : :...|.......|:..:..|                      .|.||.:|.......|
 Frog   374 LNMADGTRTRVEQQRENQDQNA----------------------VPLAVTEGRPRLNHHN----- 411

  Fly   395 ALPPNFADLFGD--ASGLPN------------GLPNLAGLQI--PPPPVMPMISPFMIPPHFGYL 443
                :|....|.  ||.||:            ||...:..|:  ....|:.|.
 Frog   412 ----HFFHFDGSRFASWLPSFSVEVMHTTNILGLAQASNSQLNAMARQVLDMF------------ 460

  Fly   444 TPLPPPPIPQDLTNFTDEELRAMEGLQRDHIVQRLKLLQNINLMLDSAGIMMSQYQSLSARLQLT 508
                 |.:|..|                  ::|.|:|.:::.:..|:.         |..|:|:.
 Frog   461 -----PQVPYHL------------------VLQDLQLTRSVEITTDNI---------LEGRIQVP 493

  Fly   509 AVTPATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASSASPTMPAEKVTIEDLGADADED 573
            ..|.            :.....|||     ||.:|:....:|:|:.|   |:|.: ||....:|.
 Frog   494 FPTQ------------HQDDVRSAT-----ETSEVSAQEESSTATQT---ERVNL-DLSPGLEEY 537

  Fly   574 DIPSTATEAVSIPNSDADFEENSSELGELRKRRLKFLEERNK 615
            :..|.....||   ...:||...|...:..:.|.:.|.:|.:
 Frog   538 EDFSVIEAQVS---DVEEFEARGSRFSKSAEERQRMLVQRKE 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sip3	NP_001263152.1	HRD1	20..>365	CDD:227568	88/359 (25%)
		zf-RING_2	287..328	CDD:290367	20/40 (50%)
amfr	NP_001017083.1	HRD1	75..>374	CDD:227568	84/317 (26%)
		RING-H2_AMFR	331..374	CDD:319369	22/43 (51%)
		RING-H2 finger (C3H2C3-type)	333..370	CDD:319369	19/37 (51%)
		CUE_AMFR	450..490	CDD:270604	10/83 (12%)
		G2BR	564..589	CDD:375868	3/13 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D271732at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010