Protein Alignment sip3 and LOC4576491

DIOPT Version :10

• Sequence 1: NP_651894.3
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_061506956.1
• Gene: LOC4576491 / 4576491
• VectorBaseID: AGAMI1_013392
• Length: 841
• Species: Anopheles gambiae
• Alignment Length: 650
• Identity: 148/650 - (22%)
• Similarity: 264/650 - (40%)
• Gaps: 149/650 - (22%)

  Fly    49 FVIVFMFGKLLSKIFLGTLRAAEFEHLLERFW-YALTETCLAFTVFRDDFNPR---FVALFTVLL 109
            :..:.:.||.:.|...|.||.:|.:|:.::|| :...:....|.|....:...   :|:.|:.|.
Mosquito   191 YCCLILLGKSIQKFVFGELRISEQQHMKDKFWNFIFYKFIFVFGVVNVQYLYEVILWVSWFSALG 255

  Fly   110 FLKSFHWLAEERVDFMERSPVL-GWLFHIRVGSLLTVLGILDYVLLIHAYNSTLVRGPTVQL--- 170
            ||.....|:::|.:::..||.. || .|.|:.|||..:..|          |.|:.|.::.:
Mosquito   256 FLHLLSQLSKDRFEYLSFSPTTPGW-SHFRLISLLVAILAL----------SGLMVGISIGVGVF 309

  Fly   171 -----VFGFEYA--ILLTV-IASTAIKYVLHAAEMR---------TDTP---WENKAVFLLYTEL 215
                 .|.|..|  |||:: .....|:|.:...:||         :..|   |:.:.....|.||
Mosquito   310 FGGFNTFAFMAAECILLSIRTLHVLIRYGMFLHDMRQGGIANESFSSFPAISWDKRGPVAYYIEL 374

  Fly   216 ---VIGLIKVVLYILFVVIMAKIYALPMFVFRPMFFTIRNFRKALNDVIMSRRAIRN-------M 270
               |..|:..:::.:.:::.:.|     |:.......:...|..||::....:..||       |
Mosquito   375 TFEVAALMVELVHYIHMMLWSNI-----FLSMASLVILMQLRYLLNEIQRKIKKHRNYLWVLNHM 434

  Fly   271 NTLYPDATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTP 335
            ...||.|:.::|:|:.:.|.||.|.| ..::||||.|:||.:||:||.::..:||||||.:
Mosquito   435 EKSYPLASSDDLKQNSDNCAICWEKM-ETARKLPCAHLFHNSCLQSWLEQDTSCPTCRLGL---- 494

  Fly   336 TVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARADVNVAGGQALPPNF 400
            :|:....||          |:|:             .|....:.|.:.|   |...||:....:|
Mosquito   495 SVHQNGGPR----------GSPL-------------LPDDIRIDDQDGA---VGGGGGRTANNHF 533

  Fly   401 ADLFGD--ASGLPNGLPNLAGLQIPPPPVMPMISPFMIPPHFGYLTPLPPPPIPQDLTNFTDEEL 463
            ....|.  .|.|||       ..:....:..|:.|       ....|:....:....:...:...
Mosquito   534 FHFNGSRYVSWLPN-------FSVEVTHINSMLRP-------SETLPITAAAVGNHTSQVRNMAR 584

  Fly   464 RAMEGLQR---DHIVQRLKLLQNINLMLDSAGIMMSQYQSLSARLQLTAVTP------------- 512
            ...|...|   ..::..|::.::|.:.:|:.         |..|||:.|.:|
Mosquito   585 HVQEMFPRYPLSVLIGDLQISRSIEVTIDNI---------LEGRLQVPANSPEDEDEETLGAASV 640

  Fly   513 -ATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASS-ASPTMPA----EKVTIEDLGADAD 571
             :.|::||.|.   |..........:|.|..:|.:.:||| :|.:.||    |:.|  ::..:.|
Mosquito   641 ASMAMSGSMDG---DNGDDDDELSGELSTRSLTNSLSASSLSSLSSPAGYEVERGT--NIFGNYD 700

  Fly   572 ---EDDIPSTATEAVSIPNSDADFEENSSELGELRKRRLKFL--------EERNKSAATNERTTA 625
               .||.....:.|.|:|..|. |.::..|..::.:||.:.|        .|:|||...::.:|:
Mosquito   701 ALLRDDTVEEISSATSVPLGDR-FSKSPEEREKILQRRKEQLLAMARRRYLEKNKSELNHQPSTS 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sip3	NP_651894.3	HRD1	20..>365	CDD:227568	89/353 (25%)
LOC4576491	XP_061506956.1	None