Protein Alignment sip3 and Amfr

DIOPT Version :10

• Sequence 1: NP_651894.3
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001414073.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 147/665 - (22%)
• Similarity: 259/665 - (38%)
• Gaps: 189/665 - (28%)

  Fly    33 YITKSNASMGVIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETCLAFTVFRDDF 97
            |:...:..:.|:......::.:..||:..|..|.||.:|.:||.::||        .|..:
  Rat    76 YLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFW--------NFIFY---- 128

  Fly    98 NPRFVALFTV------------------LLFLKSFHWLAEERVDFMERSPVLGWLFHIRVGSLLT 144
              :|:.:|.|                  |:||.....|.::|.:::..||......|.||.|||.
  Rat   129 --KFIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLI 191

  Fly   145 VLGI----LDYVLLIHAYNSTLVRGPTVQLVFGFEYAILLTV-IASTAIKYVLHAAEMRTDTPWE 204
            .:.:    |..|..:..|...:     ..|.|....::|:|| .|...::||:|..::..:..||
  Rat   192 AMLLSCCGLAVVCCVTGYTHGM-----HTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWE 251

  Fly   205 NKAVFLLYTELVIGLIKVVL-------YILFVVIMAKIYALPMFV-FRPMFFTI-RNFRKALNDV 260
            .|..::.||:.|:.|:.:.|       .:||..|...:.:|.:|: .|.:|..: |..|:..|.:
  Rat   252 GKGTYVYYTDFVMELMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYL 316

  Fly   261 IMSRRAIRNMNTLYPDATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCP 325
                |.:.||...:..||.|||..:::.|.||.:.| ..::||||||:||.:|||||.::..:||
  Rat   317 ----RVVGNMEARFAVATAEELAVNNDDCAICWDSM-QAARKLPCGHLFHNSCLRSWLEQDTSCP 376

  Fly   326 TCRLNILRTPTVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARAD--- 387
            |||:::                                             .:.||::||.|
  Rat   377 TCRMSL---------------------------------------------NIADGSRAREDHQG 396

  Fly   388 -------VNVAGGQALPP-NFADLF--GDASGLPNGLPNLAGLQIPPPPVMPMISPFMIPPHFGY 442
                   |.||..:..|. |..:.|  .|.|.:.:.||:.:        |..|.:..::
  Rat   397 ENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIASWLPSFS--------VEVMHTTNIL------ 447

  Fly   443 LTPLPPPPIPQDLTNFTDEELRAMEGLQRD-------HIV-QRLKLLQNINLMLDSAGIMMSQYQ 499
                       .:|..::.:|.||....::       |:| |.|::.:::.:..|:.
  Rat   448 -----------GITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEITTDNI-------- 493

  Fly   500 SLSARLQL-------TAVTPATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASSASPTMP 557
             |..|:|:       .::.|  |:|...:....|:....|:...:.....::|....:.....:.
  Rat   494 -LEGRIQVPFPVQRSDSLRP--ALNSPVERPGTDLEEGEASVQTERVPLDLSPRLEETLDFSEVE 555

  Fly   558 AEKVTIEDLGA-------DADE---------DDIPSTATEAVSIPNSDAD--------FEENSSE 598
            .|.|.:||..|       .|||         ||:...|.:.....:|:.|        .|..||:
  Rat   556 LEPVEVEDFEARGSRFSKSADERQRMLVQRKDDLLQQARKRFLNKSSEDDGASERLLPSEGTSSD 620

  Fly   599 LGELRKRRLKFLEER 613
            ...||:|.|....||
  Rat   621 PVTLRRRMLAAAAER 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sip3	NP_651894.3	HRD1	20..>365	CDD:227568	90/363 (25%)
Amfr	NP_001414073.1	None