DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sip3 and Chfr

DIOPT Version :9

Sequence 1:	NP_001263152.1	Gene:	sip3 / 43747	FlyBaseID:	FBgn0039875	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	XP_006249597.1	Gene:	Chfr / 288734	RGDID:	1306360	Length:	664	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	48/206 - (23%)
Similarity:	66/206 - (32%)	Gaps:	54/206 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 PDATPEELRQSDNICIICREDMVNHSKKL-PCGHIFHTTCLRSWFQRQQTCPTCRL---NILRTP 335
            ||...|.|     .|||| :|:::....| ||.|.|...|...|.:|...|||||.   .|.:..
  Rat   294 PDKMEETL-----TCIIC-QDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNH 352

  Fly   336 TVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARADV------NVAGGQ 394
            .:|                 |.:.|.....|             |.:::..||      |.....
  Rat   353 ILN-----------------NLVEAYLLQHP-------------DKSRSEEDVRSMDARNKITQD 387

  Fly   395 ALPPNFADLFGDASGLPNGLPNLAGLQIPPPPV-MPMISPFMIPPHFGYLTPLPPPPIPQDLTNF 458
            .|.|.....|.|..|....|..|:.:......: .|.|.....|.:........|.|:|
  Rat   388 MLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPEYRRQAVQSLPCPVP------ 446

  Fly   459 TDEELRAMEGL 469
             :.||.|.:.|
  Rat   447 -ESELGATQAL 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sip3	NP_001263152.1	HRD1	20..>365	CDD:227568	26/93 (28%)
sip3	NP_001263152.1	zf-RING_2	287..328	CDD:290367	16/41 (39%)
Chfr	XP_006249597.1	FHA	16..105	CDD:238017
		FHA	<27..140	CDD:224630
		RING	302..345	CDD:238093	18/43 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900