DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sip3 and Rnf145

DIOPT Version :9

Sequence 1:NP_001263152.1 Gene:sip3 / 43747 FlyBaseID:FBgn0039875 Length:626 Species:Drosophila melanogaster
Sequence 2:NP_001099248.1 Gene:Rnf145 / 287212 RGDID:1309561 Length:664 Species:Rattus norvegicus


Alignment Length:457 Identity:103/457 - (22%)
Similarity:173/457 - (37%) Gaps:127/457 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 VIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETC--------LAFTVFRDDFNP 99
            |:::.|:::  :|...:...|....:.|..|.||..|..::.|.|        |.|||       
  Rat   229 VLFMVFWLV--LFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTV------- 284

  Fly   100 RFVALFTVLL---FLKSFHWLAEE-----------------------RVDFMERSPVLGWLFHIR 138
            .||||..:.|   :|:.:.....:                       .:..:.|:.:|..:..|.
  Rat   285 SFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIV 349

  Fly   139 VGSLL-TVLGILD-------------------------YVLLIHAYNSTLVRGPTVQLVFGFEYA 177
            |.|:| ::|.|.|                         ::|:..||.:.::    .|. |..::.
  Rat   350 VASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMI----CQF-FHMDFW 409

  Fly   178 ILLTVIAS---------TAIKYVLHAAEMRTDTPWENKAVFLLYTELVIGLIKVVLYILFVVIMA 233
            :|:.:.:|         |...|||...|.....|.||....:.|   |.|..:::.:::.:.::|
  Rat   410 LLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYY---VNGTYRLLEFLVALCVVA 471

  Fly   234 KIYALPMF----VFRPMFFTIRNF-----RKAL--NDVIMSRRAIRNMNTLYPDATPEELRQSDN 287
            ...:..:|    |...|...|.::     |..|  ...::.|.|:..:.:| |.||.|:|.:.::
  Rat   472 YGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSL-PIATKEQLERHND 535

  Fly   288 ICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTVNSTAMPRQGDE---- 348
            ||.||.:|| ..:...||.|.||..||:.|...|.|||.|..::     .||:.:|..|.|    
  Rat   536 ICAICYQDM-KSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHL-----KNSSQLPGLGTEPAPQ 594

  Fly   349 -AVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARADVN-----------------VAGGQA 395
             .||.|..| |....|.:|.....||.|.|..........:|                 :|.|:|
  Rat   595 PPVAGAEQN-IVLQEGPEPPDHETPPGPGAQEGSGDNSEYINRSSASREGDADPGDGPQIAEGEA 658

  Fly   396 LP 397
            .|
  Rat   659 CP 660

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sip3NP_001263152.1 HRD1 20..>365 CDD:227568 93/406 (23%)
zf-RING_2 287..328 CDD:290367 18/40 (45%)
Rnf145NP_001099248.1 TRC8_N 8..506 CDD:404574 55/293 (19%)
HRD1 <520..643 CDD:227568 42/130 (32%)
RING-H2_RNF145 533..575 CDD:319598 18/42 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166349148
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5243
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D897451at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.750

Return to query results.
Submit another query.