Protein Alignment sip3 and sel-11

DIOPT Version :10

• Sequence 1: NP_651894.3
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_505969.1
• Gene: sel-11 / 179612
• WormBaseID: WBGene00004768
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 261/667 - (39%)
• Similarity: 358/667 - (53%)
• Gaps: 121/667 - (18%)

  Fly     3 LLLSSVCMALTSAVIGFAYYQKQQFYPAVVYITKSNASMGVIYIQFFVIVFMFGKLLSKIFLGTL 67
            |::...|:| |:|.|..|:...:||||::||::||||||.|||:|..|:|::..:||..|..|.|
 Worm     7 LMIGGSCVA-TAATILNAFLINKQFYPSIVYLSKSNASMAVIYVQGIVLVYLMFQLLKSILFGDL 70

  Fly    68 RAAEFEHLLERFWYALTETCLAFTVFRDDFNPRFVALFTVLLFLKSFHWLAEERVDFMERSPVLG 132
            ||||.|||.||.|:|:.|||||||||||||:..||..|..|||:|.|||||::|||.||||||:.
 Worm    71 RAAEAEHLSERTWHAVLETCLAFTVFRDDFSAIFVMQFIGLLFIKCFHWLADDRVDMMERSPVIT 135

  Fly   133 WLFHIRVGSLLTVLGILDYVLLIHAYNSTLVRGPTVQLVFGFEYAILLTVIASTAIKYVLHAAEM 197
            ..||:|:.::|..||..|...:..||.:|:.||.:.|:||||||||||.::....|||:||..::
 Worm   136 LRFHLRMMTVLAALGFADSYFVSSAYFTTITRGASAQIVFGFEYAILLALVLHVTIKYLLHMHDL 200

  Fly   198 RTDTPWENKAVFLLYTELVIGLIKVVLYILFVVIMAKIYALPMFVFRPMFFTIRNFRKALNDVIM 262
            |....|:||||:|||.||.|.||:.:||..|.|:|.:::..|:|..||.:.::|...||..|||:
 Worm   201 RNPQSWDNKAVYLLYAELFINLIRCLLYGFFAVVMLRVHTFPLFSVRPFYQSVRALHKAFLDVIL 265

  Fly   263 SRRAIRNMNTLYPDATPEELRQSDNICIICREDM-VNHS-KKLPCGHIFHTTCLRSWFQRQQTCP 325
            |||||..||:.:|..:.|:|...|..||||||:| |:.| |:|||.|:||..|||||||||||||
 Worm   266 SRRAINAMNSQFPVVSAEDLAAMDATCIICREEMTVDASPKRLPCSHVFHAHCLRSWFQRQQTCP 330

  Fly   326 TCRLNILRTPTVNSTAMPRQGDEAVAAAAGNPIPAA--------AGVQPAGGVPPPAPTAVVDGN 382
            |||.:|.:         .|.|    |||.||...||        ||.|...|:||..|..   |:
 Worm   331 TCRTDIWQ---------GRNG----AAAGGNAADAAANVADANVAGAQIGAGMPPFLPFL---GH 379

  Fly   383 QARADVNVAGGQALPPNFADLFGDASGLPNGL---------PNLAGLQIPPPPVMPMISPFMIPP 438
            |.......||.....|..|...|.....|:.:         |....| ||||| :||..    ||
 Worm   380 QFGFPQQPAGAGGAQPGAAQAGGQPGPFPHQIFYAPAPANRPEFMNL-IPPPP-LPMAG----PP 438

  Fly   439 HFGYLTPLPPPPIPQ----------------DLTNFTDEELRAMEGLQRDHIVQRLKLLQNINLM 487
              |....:||||:||                ..:..:.||||.|||..|:.::.||:.:.||.::
 Worm   439 --GMFPMMPPPPLPQVNTTQGTSSETPPVNPSYSQLSTEELRRMEGESREALLARLQAMDNIMVL 501

  Fly   488 LDSAGIMMSQYQSLSARLQLTAVTPATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASSA 552
            |:||.:.|         :||..|||                         :....|.|:..:...
 Worm   502 LESAQMQM---------IQLATVTP-------------------------IRPRPVVPSDESEQE 532

  Fly   553 SPTMPAEKVTIEDLGADADEDDIPSTA-------TEAVS----IPNSDADFEENSS--------- 597
            :|....::||       ::|.:||:|:       ||:.|    .|::.:....:|:
 Worm   533 APGPSTDQVT-------SEEQEIPATSSAPSIFRTESPSTSSTAPSTSSPVTASSTPTTSSTRTP 590

  Fly   598 ELGELRKRRLKFLEERN 614
            |..|:|:|||..|...|
 Worm   591 EAEEVRQRRLARLLGEN 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sip3	NP_651894.3	HRD1	20..>365	CDD:227568	181/354 (51%)
sel-11	NP_505969.1	HRD1	51..>333	CDD:227568	150/281 (53%)