Protein Alignment Smvt and Slc5a2

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_072112.2
• Gene: Slc5a2 / 64522
• RGDID: 620217
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 518
• Identity: 109/518 - (21%)
• Similarity: 212/518 - (40%)
• Gaps: 72/518 - (13%)

  Fly    25 NATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIP 89
            |..|..|.|....:...:|:: ..|.....|...|.:.|:.|...|:..||.||.:.:...:.:.
  Rat    20 NPADILVIAAYFLLVIGVGLW-SMFRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLA 83

  Fly    90 AEMYAYGI---NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF-CRKVR----VLQT 146
            ....|.|:   .:.:|.:.:||   ||.:|.:||:....:....:||..|| .|::|    ||..
  Rat    84 GTGAASGLAVAGFEWNALFVVL---LLGWLFVPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSL 145

  Fly   147 FIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMV 211
            |::|.|   .:.:.:|..::...|..|:|::.....:..|.:.||:.||:.|:::||.:|..:::
  Rat   146 FLYIFT---KISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVIL 207

  Fly   212 ASVVLVGVLGAHRVGGFFEVL-RIAGEGGRLDI-------------------NYNF--DLTTRST 254
            |...::.....|.|||:..:. :..|....|.:                   :|:.  |..|...
  Rat   208 AGAFILTGYAFHEVGGYSGLFDKYLGAVTSLTVSKDPAVGNISSTCYQPRPDSYHLLRDPVTGDL 272

  Fly   255 IW-NIFTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRF 318
            .| .:....|::...|...:|..|||.::..:|.|.:...:|.|:..::.||.....|::....:
  Rat   273 PWPALLLGLTIVSGWYWCSDQVIVQRCLAGKNLTHIKAGCILCGYLKLMPMFLMVMPGMISRILY 337

  Fly   319 HD---------CDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLG 374
            .|         |..:....|...:...|..|...:.|  |:.|:.::.:.:|.:|:|::..||..
  Rat   338 PDEVACVVPEVCKRVCGTEVGCSNIAYPRLVVKLMPN--GLRGLMLAVMLAALMSSLASIFNSSS 400

  Fly   375 GVVYFD-YIKPHIRHTEHRANVIMKLFVFFTGIYCILGGMVIE--NFNSILQVIYSIGGMSFGST 436
            .:...| |.:...|..:....::.:|:|.|.....:....|::  ....:...|.|:........
  Rat   401 TLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVAVSVAWLPVVQAAQGGQLFDYIQSVSSYLAPPV 465

  Fly   437 CGVFMLGMLVPKSHGRAALVGVLASIACMATIVILSWGRNHYDTLP---------TSTSACPA 490
            ..||:|.:.||:.:.:.|..|::..:       ::...|    .:|         ...|||||
  Rat   466 SAVFVLALFVPRVNEKGAFWGLIGGL-------LMGLAR----LIPEFFFGTGSCVRPSACPA 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	108/516 (21%)
Slc5a2	NP_072112.2	SLC5-6-like_sbd	22..670	CDD:444915	108/516 (21%)