Protein Alignment Smvt and Slc5a4b

DIOPT Version :9

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_075708.2
• Gene: Slc5a4b / 64454
• MGIID: 1890478
• Length: 660
• Species: Mus musculus
• Alignment Length: 630
• Identity: 141/630 - (22%)
• Similarity: 259/630 - (41%)
• Gaps: 153/630 - (24%)

  Fly     1 MSSLLNATVLATAAT----VVPDSQFVFNATDYGVFALVLSISAAIGVYF----------GFFAK 51
            |:|.|:.::  |..|    |||..  :.||.|..|..:...:..|:|::.          |||..
Mouse     1 MASTLSPSI--TPQTEEPPVVPVR--IQNAADISVIVIYFIVVLAVGLWSMVRSNRGTVGGFFLA 61

  Fly    52 GEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIPAEMYAYGI-----NWVFNVVCMVLVVP 111
            |.|           |...|:..||.||.:.:...:.:.....|.||     .|  |.:.||||
Mouse    62 GHD-----------MAWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEW--NALLMVLV-- 111

  Fly   112 LLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTFIFILTMFFMLPI----FIFLPSLAFAQVT 172
             |.::.:|::....:....|||..||..|  .||.::.:|::|.|:.:    .||..::......
Mouse   112 -LGWVFLPIYIKAGVLTMPEYLRKRFGGK--RLQIYLSVLSLFIMVALQTSSIIFSGAIFIQLAL 173

  Fly   173 GFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIM-VASVVLVGVLGAHRVGG-------FF 229
            |.|::|...::.:|..|||:.||:.:|::||.:|..|| :.|::|:|...| .|||       :.
Mouse   174 GLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFA-EVGGYESFTEKYM 237

  Fly   230 EVLRIAGEGGRLDIN---YNFDLTTRSTIWNIF---TSATMMWTGYV-GL----------NQSCV 277
            ..:....||..|.|:   |    |.:...:::|   .:..:.|.|.: |:          :|..|
Mouse   238 NAIPSVVEGDNLTISPKCY----TPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYWCADQVIV 298

  Fly   278 QRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVSKVDKM------- 335
            ||.:...::.|.:.:.:|.|:..:|.||.....|::  ||....|.:.....|:.:|.
Mouse   299 QRCLCGKNMSHVKAACILCGYLKLLPMFLMVMPGMI--SRILYTDKVACVVPSECEKQCGTAVGC 361

  Fly   336 ----VPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFD-YIKPHIRHTEHRANV 395
                .|..|.:.:.:  |:.|:.:|.:.::.:|:|::..||...:...| |.|...:.:|....:
Mouse   362 TNYAYPTLVLELMPD--GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRKKASERELMI 424

  Fly   396 IMKLFVFFTGIYCILGGMVIENFNSIL-----------QVIYSIGGMS--FGSTCG-VFMLGMLV 446
            ..::|           |||:... |||           |:.:.||.:|  .|...| ||||.:..
Mouse   425 AGRIF-----------GMVLIAV-SILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFF 477

  Fly   447 PKSHGRAALVGVLAS--IACMATIVILSWGRNHYDTLPTSTSACPASLNGTIKDISTASPLFLGS 509
            .:.:.:.|..|::..  :..:..|....:|          |.:|.|..|         .|..
Mouse   478 KRVNEQGAFWGLMVGLVVGLIRLIAEFVYG----------TGSCVAPSN---------CPKI--- 520

  Fly   510 TTEAPVGEKEFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPD 554
                        |..:.:.::.:..|.::.::.:.:|::.:..||
Mouse   521 ------------ICGVHYMYFAIILFFVSIIVILGVSFLTEPIPD 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	129/592 (22%)
Slc5a4b	NP_075708.2	SLC5-6-like_sbd	27..660	CDD:294310	131/600 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740