Protein Alignment Smvt and slc5a9

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001107077.1
• Gene: slc5a9 / 564815
• ZFINID: ZDB-GENE-080513-3
• Length: 657
• Species: Danio rerio
• Alignment Length: 674
• Identity: 154/674 - (22%)
• Similarity: 263/674 - (39%)
• Gaps: 157/674 - (23%)

  Fly    14 ATVVPD---SQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISL 75
            ||..|:   ::|...|.|..|..:......|:|::....| ...|...|.:.|:.|...||..||
Zfish    10 ATPEPEEVPAKFTLEAADIAVVVVYFVFVLAVGIWSSIRA-NRGTVGGYFLAGRSMTWWPIGASL 73

  Fly    76 VASQLSAISIMTIPAEMYAYGI---NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF 137
            ::|.:.:...:.:.....|.|:   .:.:|...:::.   |.::.:||:.:..:....|||..||
Zfish    74 MSSNVGSGLFIGLAGTGAAGGLAVGGFEWNAAWVLIA---LGWIFVPVYISAGVVTMPEYLRKRF 135

  Fly   138 -CRKVR----VLQTFIFILTMFFMLPIFIFLPSLAFAQVT-GFNVHLINTVVCSICVFYTMFGGI 196
             .:::|    ||...::|||   .:...||..:| |.||: |::::|...::.::...||:.||:
Zfish   136 GGQRIRIYMSVLSLILYILT---KISTDIFSGAL-FIQVSLGWDLYLSTVILLAVTALYTIAGGL 196

  Fly   197 KAVVWTDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGG--------------RLDINYNF 247
            .||::||.:|..|||....::..:...:| |::|.|.:..|..              |.|..:.|
Zfish   197 TAVIYTDALQTVIMVIGAFVLMFIAFDKV-GWYEGLLVQYEKAAPALTVPNTTCHLPRSDAFHIF 260

  Fly   248 ------DLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFF 306
                  |:.....|:.:...||.:|.    .:|..|||.:|..:|.||:...||.|:..:..|||
Zfish   261 RDPVTGDIPWPGLIFGLTVLATWVWC----TDQVIVQRSLSAKNLSHAKAGSVLGGYLKVFPMFF 321

  Fly   307 NCFTGIVIYSRFHD---------CDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAA 362
            ....|::..:.:.|         |..|....|...:...|..|.:.:.  .||.|:.|:.:.:|.
Zfish   322 VVMPGMISRALYPDEVACVDPDECQKICGAKVGCSNIAYPKLVVELMP--VGMRGLMIAVMMAAL 384

  Fly   363 LSTLSASINSLGGVVYFDY---IKPHIRHTEHRANVIMKLFVFFTGIYCILGGMVIENFNS---- 420
            :|:|::..||...:...|.   |:|  |.:|....|:.::|:.......|:...||:..||
Zfish   385 MSSLTSIFNSSSTLFTMDIWQRIRP--RASEKELMVVGRVFILLLVALSIVWIPVIQTANSGQLF 447

  Fly   421 -ILQVIYSI--------------------GGMSFGSTCG--VFMLGMLVPKSHGR---------- 452
             .:|.|.|.                    .|..:|...|  |.|:.|::...:|.
Zfish   448 DYIQAITSFLSPPITTVFIMAIFWGRVNEQGAFWGLMVGLVVGMVRMIMEFVYGTPSCGETDLRP 512

  Fly   453 ----------------AALVGVLASIA-CMATI-----VILSWGRNHYDTLPTSTS---ACPASL 492
                            |..|.::.::: |.|.|     |.|:|...|.........   |.||.
Zfish   513 SLLKDVHYLYFALILLALTVLIITAVSLCTAPIPEKHLVRLTWWTRHSKEERVELEDPWAKPAG- 576

  Fly   493 NGTIKDISTASPLFLGSTTEAPVGEKEFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKP 557
                .|:||...  .||..:||.             |:...|.   ||.|  ||...|..
Zfish   577 ----SDLSTTES--EGSDEDAPA-------------WWKRAGM---WLCG--LSQTTKQD----- 612

  Fly   558 NPKLLSPVVQPFVHYKLTPSDEPH 581
                |:...:..:..|||..:|.|
Zfish   613 ----LTEEERQALEKKLTSIEEDH 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	142/623 (23%)
slc5a9	NP_001107077.1	SLC5sbd_SGLT4	42..657	CDD:271380	146/642 (23%)