DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smvt and salt

DIOPT Version :9

Sequence 1:	NP_651891.2	Gene:	Smvt / 43744	FlyBaseID:	FBgn0039873	Length:	591	Species:	Drosophila melanogaster
Sequence 2:	NP_651889.3	Gene:	salt / 43742	FlyBaseID:	FBgn0039872	Length:	622	Species:	Drosophila melanogaster

Alignment Length:	610	Identity:	310/610 - (50%)
Similarity:	419/610 - (68%)	Gaps:	31/610 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSLLNATVLATAATVVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKR 65
            :|:|.:....||.||:   ....|:.|||.||:|:||.||.||||||||:|.::||||||.||||
  Fly     5 VSNLASTVATATTATL---EDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKR 66

  Fly    66 MKTIPIAISLVASQLSAISIMTIPAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCY 130
            |.|:|:|||||:||||.:::|::|||.|::|.|.:|.|..|||.||:|.|:::||||:||::|||
  Fly    67 MPTLPVAISLVSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCY 131

  Fly   131 EYLEMRFCRKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGG 195
            ||||:||.::.|.|.|..|||..|.|||:::|:|||||:||||:|:|||||||.||||||||.||
  Fly   132 EYLELRFSKRTRQLVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGG 196

  Fly   196 IKAVVWTDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDINYNFDLTTRSTIWNIFT 260
            |||||||||:|.::|:.|||||.:||....||...||..|.||||.|.::..|...|.|..:...
  Fly   197 IKAVVWTDVVQGSVMLISVVLVAILGTSNTGGITNVLENAAEGGRFDFSFGIDPRLRLTFISGMA 261

  Fly   261 SATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQ 325
            |..:||||.:||:||||||||||||.|||:|.|::.|.||:|||.|.|||||::::.::.|||||
  Fly   262 SGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQ 326

  Fly   326 SGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKPHIRHTE 390
            :|.|||.||::|:|:||.:|::.|||||||||||||:||:||||:||..||||||||||.|.|:|
  Fly   327 AGLVSKPDKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSE 391

  Fly   391 HRANVIMKLFVFFTGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAAL 455
            .:||..|||.:...|.|||:||.:::|||||:|.:::|.|::.|:..|||.|||.||:.:.:.|:
  Fly   392 AKANATMKLVIVVMGAYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAV 456

  Fly   456 VGVLASIACMATIVI-----LSWGRNHYDTLPTSTSACPAS---------LNGTIKDI-STASPL 505
            .|:..|...|..|:|     ...|...||.||.....|.|.         .|..:.:: :||.|
  Fly   457 SGIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIP- 520

  Fly   506 FLGSTTEAPV-------GEKEFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKPNPKLLS 563
                :.|||.       ..::|||.|.||.||.|.|.::.:...||:||:.....:.|.||||.|
  Fly   521 ----SLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYS 581

  Fly   564 PVVQPFVHYKLTPSDEPHQLNLEKP 588
            |.|:..:: |.:|..|..:|.|:.|
  Fly   582 PFVRSMLN-KPSPVLELEELPLKTP 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	288/542 (53%)
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	288/542 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468688
Domainoid	1	1.000	45	1.000	Domainoid score	I12178
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	1	1.000	-	-		H64794
Inparanoid	1	1.050	579	1.000	Inparanoid score	I2526
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	11	10.900