Protein Alignment Smvt and slc5a8

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001351880.1
• Gene: slc5a8 / 394505
• XenbaseID: XB-GENE-479634
• Length: 620
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 197/563 - (34%)
• Similarity: 300/563 - (53%)
• Gaps: 47/563 - (8%)

  Fly    16 VVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQL 80
            |.|.:...|...||.||||:|.|||.||:|:.|...|:.|::::||||:.|..:|:|:||.||.:
 Frog     2 VTPGNIGSFTVWDYVVFALMLLISAVIGIYYAFAGGGQKTSKDFLMGGRSMTAVPVALSLTASFM 66

  Fly    81 SAISIMTIPAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQ 145
            ||::::..|||:|.:|..:........:||.:.:.:.:||||...||:.|||||:||.:.||:|.
 Frog    67 SAVTVLGTPAEVYRFGSMFSIFAFTYAIVVVISSEVFLPVFYRLGITSTYEYLELRFNKFVRLLG 131

  Fly   146 TFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCS--ICVFYTMFGGIKAVVWTDVIQAA 208
            |.:||:.......|.|:.|:||..|||||:  |...||.:  :|.||...||:||||||||.|..
 Frog   132 TILFIIQTVLYTGIVIYAPALALNQVTGFD--LWGAVVATGVVCTFYCTMGGLKAVVWTDVFQVG 194

  Fly   209 IMVA---SVVLVGVLGAHRVGGFFEVLRIAGEGGRLDINYNFDLT----TRSTIWNIFTSATMMW 266
            ||||   ||::..|:..   ||...:|..:..|.||:.   :|.|    .|.:.|.|....|..|
 Frog   195 IMVAGFSSVIIRAVVVQ---GGIGPILNDSYYGDRLNF---WDFTPNPLQRHSFWTIVVGGTFTW 253

  Fly   267 TGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVSK 331
            ||..|:|||.|||.::..:...|:.||.:...|...|:.....:|:.:||.:.||||..:..||.
 Frog   254 TGIYGVNQSQVQRYIACKTRFQAKLSLYINLLGLWAILACAVLSGLAMYSIYKDCDPWTAQFVSA 318

  Fly   332 VDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKPHIRH-TEHRANV 395
            .|:::||...|.:.:..|:||:|:||.:|..|||:|:|||:|..|...|.|||:.|. :|.:.:.
 Frog   319 PDQLMPYLSLDILRDYPGLPGLFVSCAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSETKMSW 383

  Fly   396 IMKLFVFFTGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGVLA 460
            |.|......|..||....:......:||...||.||..|...|:|.||::.|..:...|::|:|:
 Frog   384 ISKGTSLIYGAICIAMAGLASLMGGLLQAALSIFGMVGGPLLGLFALGIIFPFVNSLGAVIGLLS 448

  Fly   461 SIACMATIVILSWGRNHYDTLPTSTSACPASL------------NGTIKDISTASPLFLGSTTEA 513
            ..|....:.|   |...|.  ||::|:.|..|            |.|    :|..|:.   ||..
 Frog   449 GFAISLWVGI---GSQIYP--PTASSSLPKPLSLEGCNFTSFESNWT----TTVMPMM---TTLI 501

  Fly   514 PVGEKEFSILD----LSFNWYTVTGFVITWLIGIPLSYILKSG 552
            |.......:.|    ||:.:::..|.::..::|: ::.:|..|
 Frog   502 PEVSSRPELADSWYSLSYLYFSTLGTIVAVVVGV-IASLLSGG 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	192/546 (35%)
slc5a8	NP_001351880.1	SLC5sbd_SMCT1	7..547	CDD:271402	195/558 (35%)