Protein Alignment Smvt and slc5a1

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_956975.1
• Gene: slc5a1 / 393654
• ZFINID: ZDB-GENE-040426-1524
• Length: 658
• Species: Danio rerio
• Alignment Length: 512
• Identity: 122/512 - (23%)
• Similarity: 216/512 - (42%)
• Gaps: 52/512 - (10%)

  Fly    22 FVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIM 86
            :|.|..|..|..:...:..|:||: ........|...:.:.|:.|...||..||.||.:.:...:
Zfish    22 YVNNPADISVIVIYFLVVLAVGVW-AMVRTNRATVGGFFLAGRSMVWWPIGASLFASNIGSGHFV 85

  Fly    87 TIPAEMYAYGI---NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF-CRKVRV-LQT 146
            .|.....|.||   .:.:|.:.:|::   |.:|.:|::....:....|||:.|| .:::|: |..
Zfish    86 GIAGTGAAAGIAIGGFEWNALVVVII---LGWLFVPIYIKAGVVTMPEYLKKRFGGQRIRIYLSV 147

  Fly   147 FIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIM- 210
            ....|.:|..:...:|..::...|..|.|::|...::..|...||:.||:.||::||.:|..||
Zfish   148 LSLCLYVFTKISADMFAGAIFINQALGLNIYLAVVILLLITALYTVTGGLAAVIYTDTLQTIIMV 212

  Fly   211 VASVVLVGVLGAHRVGGF--FEVLRIAGEGGRLDINYNFD-LTTRSTIWNIF---TSATMMWTGY 269
            |.|.:|:| ...::|||:  |....:......:..|.:.. .|.|:..::||   .:..:.|.|.
Zfish   213 VGSFILMG-FAFNKVGGYENFRDSYMTAIPSVIGTNISESCYTPRADSFHIFRDPINGDLPWPGL 276

  Fly   270 V-GL----------NQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHD--- 320
            : ||          :|..|||.:|..:|.|.:...:|.|:..:|.||...|.|::....:.|
Zfish   277 LFGLTIQAGWYWCTDQVIVQRCLSAKNLSHVKAGCILCGYLKLLPMFLMVFPGMISRVLYPDEIA 341

  Fly   321 ------CDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYF 379
                  |..:....|...:...|..|.|.:.|  |:.|:.:|.:.::.:|:|::..||...:...
Zfish   342 CVDPDECKAVCGAEVGCTNIAYPKLVVDLMPN--GLRGLMLSVMLASLMSSLTSIFNSASTLFTM 404

  Fly   380 D-YIKPHIRHTEHRANVIMKLFVFFTGIYCILGGMVIENFNS--ILQVIYSIGGMSFGSTCGVFM 441
            | |.|...:..|....:..:||:.......|....:::...|  :...|.||..........||.
Zfish   405 DIYTKIRPKAKEKELMIAGRLFMLLLIGISIAWIPIVQTAQSGQLFDYIQSITSYLAPPIAAVFA 469

  Fly   442 LGMLVPKSHGRAAL----VGVLASIACMATIVILSWGRNHYDTLPTSTSACPASLNG 494
            |.:...:.:...|.    ||:|..:|.|.|......|.      ..:.|.||..:.|
Zfish   470 LAIFCKRVNEPGAFYGLCVGLLVGLARMITEFAYGTGS------CVNPSNCPTIICG 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	120/507 (24%)
slc5a1	NP_956975.1	SLC5sbd_SGLT1	27..658	CDD:271379	120/507 (24%)