Protein Alignment Smvt and Slc5a9

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001382057.1
• Gene: Slc5a9 / 366441
• RGDID: 1311383
• Length: 688
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 154/679 - (22%)
• Similarity: 259/679 - (38%)
• Gaps: 188/679 - (27%)

  Fly    29 YGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIPAEMY 93
            |.||.|.:.|.::|....|       |...|.:.|:.|...||..||::|.:.:...:.:.....
  Rat    43 YFVFVLAVGIWSSIRASRG-------TIGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGA 100

  Fly    94 AYGI---NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF-CRKVRVLQTFI-FILTM 153
            |.|:   .:.:|...::|.   |.::.:||:....:....:||:.|| .::::|..:.: .||.:
  Rat   101 AGGLAVGGFEWNATFLLLA---LGWIFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYI 162

  Fly   154 FFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVG 218
            |..:...||..:|......|:|::|...::..:...||:.||:.||::||.:|..|||...:::.
  Rat   163 FTKISTDIFSGALFIQMALGWNLYLSTVILLVVTAVYTIAGGLTAVIYTDALQTVIMVGGALVLM 227

  Fly   219 VLGAHRVGGF----------------------------FEVLRIAGEGGRLDINYNFDLTTRSTI 255
            .||...||.:                            |.:||....|         |:.....|
  Rat   228 FLGFREVGWYPGLQQLYRQSIPNVTVPNTTCHLPRSDAFHMLRDPVNG---------DIPWPGLI 283

  Fly   256 WNIFTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHD 320
            :.:...||..|.    .:|..|||.:|..||.||:...||.|:..||.|||....|::..:.:.|
  Rat   284 FGLTVLATWCWC----TDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALYPD 344

  Fly   321 ---------CDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGV 376
                     |..:....|...:...|..|...:.  .|:.|:.|:.:.:|.:|:|::..||...:
  Rat   345 EVACVDPDICQRVCGARVGCSNIAYPKLVMALMP--VGLRGLMIAVIMAALMSSLTSIFNSSSTL 407

  Fly   377 VYFDYIKPHIRH--TEHRANVIMKLFVFFTGIYCILGGMVIENFNS--ILQVIYSI--------- 428
            ...| :...:|.  :|....|:.:|||.|..:..||...:|::.||  :...|.||
  Rat   408 FAID-VWQRVRRQASEQELMVVGRLFVVFLVLISILWIPIIQSSNSGQLFDYIQSITSYLAPPIT 471

  Fly   429 ------------------GGMSFGSTCGVFMLGMLVPKSHGRAA--------------------- 454
                              .|:.||...|:  |.|::..|:...|
  Rat   472 ALFLLAIFCKRVTEPGAFWGLMFGLVVGI--LRMILEFSYSAPACGEKDRRPAVLKDFHYLYFAL 534

  Fly   455 -LVGVLASIACMATIVILSWGRNHYDTLPTS--------TSACP---------ASLNGTIKDIST 501
             |.|:.|.|     |||:|:   ..:.:|..        |.:||         .|:|.|..|.|.
  Rat   535 LLCGLTAII-----IVIISF---FTEPIPDEKLARLTWWTRSCPISELQKKVSVSVNNTESDNSP 591

  Fly   502 A---SPLFLG--------STTEAPVGEKEFSILDLS-----FNWYTVTGFVITWLIGIPLSYILK 550
            |   .|:..|        :||..|   ::..:|..|     :||:       ..|.|.|
  Rat   592 ALAGRPVMEGTAGDEEEANTTSEP---EQPEVLHRSWGKWLWNWF-------CGLSGTP------ 640

  Fly   551 SGPDYKPNPKLLSPVVQPFVHYKLTPSDE 579
                    .:.|||..:..:..|||..:|
  Rat   641 --------QQALSPAEKAELEQKLTSIEE 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	147/646 (23%)
Slc5a9	NP_001382057.1	SLC5-6-like_sbd	48..688	CDD:444915	151/674 (22%)