DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smvt and RGD1563815

DIOPT Version :9

Sequence 1:	NP_651891.2	Gene:	Smvt / 43744	FlyBaseID:	FBgn0039873	Length:	591	Species:	Drosophila melanogaster
Sequence 2:	XP_006256382.1	Gene:	RGD1563815 / 365549	RGDID:	1563815	Length:	695	Species:	Rattus norvegicus

Alignment Length:	491	Identity:	104/491 - (21%)
Similarity:	193/491 - (39%)	Gaps:	84/491 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMT 87
            :.:..|..|....|.:...||:: ...:....|.:::.:.|:.:....:.:|:.:|.:.:...|.
  Rat    21 IHSTVDTLVMTFYLLLVLCIGLW-ALLSHSRGTIKDFFLAGQNLAWWLMGLSIYSSTVGSGHFMG 84

  Fly    88 IPAEMYAYGI-----NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTF 147
            :.....|.||     .|  |.|.|:.   :|.::.:|::....:....|||:.|| ..||:...|
  Rat    85 LAGIGAASGIAVGAFEW--NTVFMLF---MLGWIFVPIYSKAGVVTLPEYLKKRF-GSVRIQLFF 143

  Fly   148 IFILTMFFML---PIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAI 209
            .|:..:.::|   .:.|...::....|...:::.....|.:|...||:.||:..|.:.:.:||.|
  Rat   144 SFVFLIVYILSRISMEIGFGAMFLKMVWDIDIYQTMLTVLTITGVYTITGGLATVAYVETLQAGI 208

  Fly   210 MVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDI---NYNFD---LTTRSTIWNIF---TSATMM 265
            ||....|:.....:.|||:.|::....:.....|   |:...   .|.|...:::|   .|..:.
  Rat   209 MVLGSALLMGYAFYEVGGYQELVNKYSKAIPSTIQQGNWTAKPECYTPREDAFHVFRSCVSGDVP 273

  Fly   266 WTG-----------YVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFH 319
            |.|           |...:|..|||.::..|..|.....:|.|:..:|.||.....|::  ||..
  Rat   274 WPGLVLGATTVSLFYGCADQVSVQRFLAGKSRLHMEGGCLLCGYLKLLPMFLMVMPGMI--SRVL 336

  Fly   320 DCDPIQSGHVSKVDKM-----------VPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSL 373
            ..|.:.....|:.:|.           .|..|...:.:  |:.|..:|.|.::.:|:|::..||.
  Rat   337 FPDQVACVVPSECEKFCGRGTGCSALAYPVLVLGVMPS--GLQGFMLSTVCASLMSSLTSIFNSS 399

  Fly   374 GGVV---YFDYIKPHIRHTEHRANVIMKLFVFFTGIYCILGGMVIENFNS-----ILQVIYS--- 427
            ..:.   .:.:|:|  ..||....:..:.||.......|:...:||...|     .:|::.|
  Rat   400 SALFTLNIYTWIRP--TATEKELMIAGRFFVIILLAVTIVWIPIIEMAPSETLFEYMQILKSCLT 462

  Fly   428 ---------------------IGGMSFGSTCGVFML 442
                                 ..|:..|||.|||.|
  Rat   463 PSVTAVFLLAVFCKRVNEQGAFWGLILGSTIGVFRL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	104/487 (21%)
RGD1563815	XP_006256382.1	SLC5-6-like_sbd	26..695	CDD:294310	104/486 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340169
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740